Results 151 to 160 of about 832,396 (367)
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Epigenetic Control of Phenotypic Plasticity in the Filamentous Fungus Neurospora crassa
G3: Genes, Genomes, Genetics, 2016 Phenotypic plasticity is the ability of a genotype to produce different phenotypes under different environmental or developmental conditions. Phenotypic plasticity is a ubiquitous feature of living organisms, and is typically based on variable patterns ...
Ilkka Kronholm +2 more
doaj +1 more source
Multi-objective optimization shapes ecological variation [PDF]
, 2013 Ecological systems contain a huge amount of quantitative variation between and within species and locations, which makes it difficult to obtain unambiguous verification of theoretical predictions.
Kaitaniemi, Pekka +3 more
core
A Potential Role for Phenotypic Plasticity in Invasions and Declines of Social Insects
Frontiers in Ecology and Evolution, 2019 Eusociality, a form of animal social organization involving sterile and reproductive castes, is a rare but, arguably, a highly ecologically successful form of life.
F. Manfredini, M. Arbetman, A. Toth
semanticscholar +1 more source
Phenotypic integration may constrain phenotypic plasticity in plants
Oikos, 2009 Phenotypic plasticity is essential for plant adaptation to changing environments but some factors limit its expression, causing plants to fail in producing the best phenotype for a given environment. Phenotypic integration refers to the pattern and magnitude of character correlations and it might play a role as an internal ...
Gianoli, E., Palacio-Lopez, K.
openaire +3 more sources
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Phenotypic plasticity as a mechanism of cave colonization and adaptation
eLife, 2019 A widely accepted model for the evolution of cave animals posits colonization by surface ancestors followed by the acquisition of adaptations over many generations.
H. Bilandžija +10 more
semanticscholar +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Sensory Ecology of Predator-Induced Phenotypic Plasticity
Frontiers in Behavioral Neuroscience, 2019 Ecological communities are organized in trophic levels that share manifold interactions forming complex food webs. Infochemicals can further modify these interactions, e.g., by inducing defenses in prey. The micro-crustacean Daphnia is able to respond to
Linda C. Weiss
semanticscholar +1 more source