How stabilizing selection and nongenetic inheritance combine to shape the evolution of phenotypic plasticity [PDF]
, 2019 Nicholas A. Levis, David W. Pfennig
openalex +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Does phenotypic plasticity initiate developmental bias?
Evolution & Development, 2019 The generation of variation is paramount for the action of natural selection. Although biologists are now moving beyond the idea that random mutation provides the sole source of variation for adaptive evolution, we still assume that variation occurs ...
K. Parsons +3 more
semanticscholar +1 more source
Individual variation in phenotypic plasticity of the stress axis [PDF]
, 2019 Sarah Guindre‐Parker +7 more
openalex +1 more source
Adaptive phenotypic plasticity: consensus and controversy
Trends in Ecology & Evolution, 1995 Phenotypic plasticity is an environmentally based change in the phenotype. Understanding the evolution of adaptive phenotypic plasticity has been hampered by dissenting opinions on the merits of different methods of description, on the underlying genetic mechanisms, and on the way that plasticity is affected by natural selection in a heterogeneous ...
Via, S. +5 more
openaire +3 more sources
Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source
Cryptic Species: A Mismatch between Genetics and Morphology in Millepora [PDF]
, 2012 Millepore morphology is highly variable and shows signs of phenotypic plasticity. Two species of Millepora are present around the islands of the Bahamas: one exhibiting a strong, blade-like structure, Millepora complanata, and the other having a delicate
Greenstein, Benjamin J., Tepper, Craig
core +1 more source
Polyphenism – A Window Into Gene-Environment Interactions and Phenotypic Plasticity
Frontiers in Genetics, 2019 Phenotypic plasticity describes the capacity of a single genotype to exhibit a variety of phenotypes as well as the mechanisms that translate environmental variation into reproducible phenotypic modifications. Polyphenism describes the unique sub-type of
Chih-Hsiang Yang, J. Andrew Pospisilik
semanticscholar +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
Large-effect flowering time mutations reveal conditionally adaptive paths through fitness landscapes in Arabidopsis thaliana. [PDF]
, 2019 Contrary to previous assumptions that most mutations are deleterious, there is increasing evidence for persistence of large-effect mutations in natural populations.
Cooper, Martha D +6 more
core