Results 71 to 80 of about 395,077 (304)
Effects of environmental perturbations during postnatal development on the phenotypic integration of the skull [PDF]
, 2011 Integration and modularity are fundamental determinants of how natural selection effects evolutionary change in complex multivariate traits. Interest in the study of the specific developmental basis of integration through experimental approaches is ...
Gonzalez, Paula Natalia +2 more
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Science Journal of University of Zakho, 2014 The study was connected to evaluate seven mays hybrids for genetic variability for yield components at Faculty of Agriculture and forestry field university of Duhok during spring 2011 and 2012 .The result show highly significant different between the ...
Mohammed O. Mohammed
doaj
Morphological Diversity and Bioactive Compounds in Wall Rocket (Diplotaxis erucoides (L.) DC.)
Agronomy, 2020 Wall rocket is a wild vegetable with interest to become a crop. However, the information regarding morphological variability in the species is scarce, despite the interest it has received for breeding programs.
Carla Guijarro-Real +3 more
doaj +1 more source
A straightforward strategy for reducing variability in flowering time at warm ambient temperatures
Plant Signaling & Behavior, 2023 Ambient temperature is one of the major environmental factors affecting flowering. As the temperature rises, most plants, including Arabidopsis, flower more rapidly.
Sol-Bi Kim, Jae-Hoon Jung
doaj +1 more source
Autosegregation of enzyme loci Me1 and Gpi2 in agamospermous progenies of triploid sugarbeet plants [PDF]
, 2010 Ratios of malic-enzyme (ME1) and glucosephosphate isomerase (GPI2) phenotypic classes were studied in agamospermous progenies of triploid sugar beet plants.
Evgenii Levites, Svetlana Kirikovich
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Epigenetic regulation of adaptive responses of forest tree species to the environment [PDF]
, 2013 Epigenetic variation is likely to contribute to the phenotypic plasticity and adaptative capacity of plant species, and may be especially important for long-lived organisms with complex life cycles, including forest trees.
Abarca, Dolores +16 more
core +4 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source