Phenotypic variance in monozygotic twins with SCA3 [PDF]
Molecular Genetics & Genomic Medicine, 2020 Background Spinocerebellar ataxia type 3 (SCA3) is a hereditary neurodegenerative disorder with high clinical heterogeneity. Twin study is valuable to estimate the contributions of gene and/or environment to phenotypic variance.
Hua Zhao +3 more
doaj +6 more sources
Phenotypic variance in Calpain-5 retinal degeneration [PDF]
American Journal of Ophthalmology Case Reports, 2020 Purpose: To characterize the phenotype of patients with mild calpain-5 Neovascular Inflammatory Vitreoretinopathy (ADNIV). Observations: The CAPN5 p.R243L mutation is typically associated with onset in the twenties and severe, progressive uveitis ...
Peter H. Tang +7 more
doaj +4 more sources
The phenotypic variance gradient - a novel concept. [PDF]
Ecol Evol, 2014 AbstractEvolutionary ecologists commonly use reaction norms, which show the range of phenotypes produced by a set of genotypes exposed to different environments, to quantify the degree of phenotypic variance and the magnitude of plasticity of morphometric and life‐history traits.
Pertoldi C +3 more
europepmc +7 more sources
Phenotypic variance explained by local ancestry in admixed African Americans [PDF]
Frontiers in Genetics, 2015 We surveyed 26 quantitative traits and disease outcomes to understand the proportion of phenotypic variance explained by local ancestry in admixed African Americans. After inferring local ancestry as the number of African-ancestry chromosomes at hundreds
Daniel eShriner +6 more
doaj +3 more sources
Estimates of genotypic and phenotypic variance, heritability, and genetic advance of horticultural traits in developed crosses of cowpea (Vigna unguiculata [L.] Walp) [PDF]
Frontiers in Plant Science, 2022 Cowpea, in addition to being a food and feed crop, plays a key role in sustainable farming. The present study’s goal is to develop new high-yielding cowpea varieties.
Haitham E. M. Zaki +2 more
doaj +2 more sources
Evolution of phenotypic variance provides insights into the genetic basis of adaptation [PDF]
Genome Biology and Evolution, 2021 Abstract Most traits are polygenic and the contributing loci can be identified by GWAS. Their adaptive architecture is, however, difficult to characterize. Here, we propose to study the adaptive architecture of traits by monitoring the evolution of their phenotypic variance during adaptation to a new environment in ...
Lai W +3 more
europepmc +4 more sources
Variant-specific inflation factors for assessing population stratification at the phenotypic variance level [PDF]
Nature Communications, 2021 Pooling participant-level genetic data into a single analysis can result in variance stratification, reducing statistical performance. Here, the authors develop variant-specific inflation factors to assess variance stratification and apply this to pooled
Tamar Sofer +15 more
doaj +2 more sources
A modeling of complex trait phenotypic variance determinants. [PDF]
PNAS NexusAbstract Studies have now shown that the heritability of some complex traits, such as human height, can be virtually fully captured via potential use of sufficiently powered approaches that can characterize the associated collective common- and rare-variant additive genetic architecture.
Hussain S.
europepmc +3 more sources
Effect of combining ability for indicators of infection of wheat galls nematode and yield in the second generation of bread wheat genotypes Triticum aestivum L. [PDF]
مجلة جامعة كركوك للعلوم الزراعية, 2022 A field experiment was carried out in the fields of a farmer in Kirkuk governorate / Hawija district N 43º36´17.73"E"05.56´ 35º16, in the winter season of 2020, and the study included a sensitivity test for 55 genotypes represented ...
Yasser Hindy, Jasim Aziz, Salih Ismail
doaj +1 more source
Partitioning the phenotypic and genetic variances of reaction norms
Peer Community JournalMany traits show plastic phenotypic variation across environments, captured by their norms of reaction. These reaction norms may be discrete or continuous, and can substantially vary in shape across organisms and traits, making it difficult to compare ...
de Villemereuil, Pierre +1 more
doaj +3 more sources