Results 111 to 120 of about 205,158 (302)
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Antibodies for DC phenotyping.
, 2019 Antibodies for DC phenotyping.
Lucia Vojtech (509660) +9 more
core +1 more source
NMR spectroscopy methods in metabolic phenotyping
, 2018 NMR spectroscopy is an established, versatile, widely applicable analytical technique forming one of the cornerstone methods for metabolic profiling, metabonomics, metabolomics, and metabolic phenotyping applied to complex biofluid and tissue samples ...
Parkinson, John A.
core +3 more sources
BMC Infectious DiseasesIntroduction Long COVID is a multisystemic, fluctuating condition inducing a high burden on affected people. Despite the existence of some guidelines, its management remains complicated.
Aurélie Fischer +8 more
doaj +1 more source
, 2022 This thesis is centered around the development and application of a digital platform for passive behavioral human subject research.This platform named Behapp (https://behapp.com), developed at the University of Groningen, makes use of mobile ‘apps’ to passively record various attributes related to social and explorative behavior through the smartphones
openaire +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Groundnut (Arachis hypogaea L.) improvement in sub-Saharan Africa: a review
Acta Agriculturae Scandinavica. Section B, Soil and Plant Science, 2019 Groundnut (Arachis hypogaea L.) is a multi-purpose legume crop widely cultivated in sub-Saharan Africa (SSA). However, yield levels of the crop has remained relatively low in SSA owing to a range of biotic, abiotic and socio-economic constraints.
Seltene Abady +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source