Results 101 to 110 of about 205,158 (302)

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

M3P: The "Montpellier Plant Phenotyping Platforms"

, 2015
The research group LEPSE, ranked among the top 5% research group in ecophysiology worldwide in 2014 by a panel of experts is developing high throughput phenotyping platforms for more than 15 years.
Welcker, Claude, Tardieu, Francois, Negre, Vincent, Brichet, Nicolas, Suard, Benoit, Mineau, Jonathan, Dauzat, Myriam, Granier, Christine, Grau, Antonin, Cabrera Bosquet, Llorenç, Muller, Bertrand   +10 more
core  

Closing the gap between phenotyping and genotyping: review of advanced, image-based phenotyping technologies in forestry

, 2022
Key message The lack of efficient phenotyping capacities has been recognized as a bottleneck in forestry phenotyping and breeding. Modern phenotyping technologies use systems equipped with various imaging sensors to automatically collect
Bian, Liming, Zhang, Huichun, Čepl, Jaroslav, Stejskal, Jan, El-Kassaby, Yousry A., Ge, Yufeng, Jaroslav Čepl, Liming Bian, Huichun Zhang, Jan Stejskal, Yousry A. EL-Kassaby, Yufeng Ge   +11 more
core   +1 more source

Asthma phenotypes

Journal of General and Family Medicine, 2017
AbstractCurrently, categorization based on cluster analysis by objectively grasping the diversity of pathology is being conducted and the diversity of asthma is being categorized as phenotypes. Clinically, there is categorization based on aging and on allergic diathesis which is clinically useful; however, it has not, up to now, come to the point of ...
Hirose, Masahiro, Horiguchi, Takahiko
openaire   +2 more sources

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Metabolic Dysfunction-Associated Steatohepatitis Detected by Neutrophilic Crown-Like Structures in Morbidly Obese Patients: A Multicenter and Clinicopathological Study

Research
Metabolic dysfunction-associated steatohepatitis (MASH) is the progressive form of metabolic dysfunction-associated steatotic liver disease (MASLD), and closely associated with a high risk of liver-related morbidity and mortality.
Mengqi Fan, Erfei Song, Yuying Zhang, Pengfei Zhang, Bing Huang, Kaixuan Yan, Wah Yang, Subrata Chakrabarti, Hema Mahajan, Sen Yan, Ying Xu, Shuang Hua, Wei Liu, Cunchuan Wang, Aimin Xu, Dewei Ye   +15 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Crop Phenotyping

, 2020
The visible form of an organism is the result of its genotype, environment and complex interaction and is referred to as phenotype. Quick, precise and non-destructive measurement of phenotypic traits has been of key importance in the field of plant ...
Sveriges lantbruksuniversitet., Ahmed, Mukhtar,   +1 more
core   +1 more source

Genetic diversity and population structure of a core collection of Mediterranean durum wheat accessions using DArTseq markers

BMC Genomics
Background Durum wheat was domesticated in the Fertile Crescent and later spread to the Mediterranean, where human and natural selection led to the establishment of local landraces.
Marwa Laribi, Sarrah Ben M’Barek, Sandra M. Velasco-Cuervo, Sheau-Fang Hwang, Amor H. Yahyaoui, Stephen E. Strelkov   +5 more
doaj   +1 more source

Body Temperature Measurements for Metabolic Phenotyping in Mice

Frontiers in Physiology, 2017
Endothermic organisms rely on tightly balanced energy budgets to maintain a regulated body temperature and body mass. Metabolic phenotyping of mice, therefore, often includes the recording of body temperature.
Carola W. Meyer, Youichirou Ootsuka, Andrej A. Romanovsky   +2 more
doaj   +1 more source