Results 81 to 90 of about 205,158 (302)

The Integrated Phenotype [PDF]

Integrative and Comparative Biology, 2012
Proper functioning of complex phenotypes requires that multiple traits work together. Examination of relationships among traits within and between complex characters and how they interact to function as a whole organism is critical to advancing our understanding of evolutionary developmental plasticity.
openaire   +2 more sources

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

A microarray platform for quantitation and phenotyping of intact exosomes

, 2016
A microarray platform for quantitation and phenotyping of intact ...
M CRETICH, F Damin, M Chiari, R Ghidoni, P Gagni, L Benussi, L Sola   +6 more
core  

Readiness of adults with type 1 diabetes and diabetes caregivers for diabetes distress monitoring using a voice-based digital health solution: insights from the PsyVoice mixed methods study

BMJ Open
Objectives Diabetes distress can negatively affect the well-being of individuals with type 1 diabetes (T1D). Voice-based (VB) technology can be used to develop inexpensive and ecological tools for managing diabetes distress.
Carine de Beaufort, Guy Fagherazzi, Aurélie Fischer, Till Seuring, Franchesca Aguirre Vergara, Gloria A Aguayo, India Pinker, Maria A Tichomirowa, Siri-Maria Kamp   +8 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Chlamydoconidium-producing Trichophyton tonsurans: Atypical morphological features of strains causing tinea capitis in Ceará, Brazil

Asian Pacific Journal of Tropical Medicine, 2019
Objective: To report atypical morphological features of Trichophyton (T.) tonsurans strains associated with tinea capitis. Methods: Eighty-two T. tonsurans strains isolated in Ceará, Brazil, were analyzed regarding macro and micromorphological features ...
Raimunda Sâmia Nogueira Brilhante, Germana Costa Paixäo, Jonathas Sales de Oliveira, Vandbergue Santos Pereira, Marcos Fábio Gadelha Rocha, Reginaldo Gonçalves de Lima-Neto, Debora de Souza Collares Maia Castelo-Branco, Rossana de Aguiar Cordeiro, Jose Julio Costa Sidrim   +8 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Distributed management of scientific workflows for high-throughput plant phenotyping [PDF]

, 2018
High-throughput phenotyping platforms allow acquisition of quantitative data on thousands of plants required for genetic analyses in well-controlled environmental conditions.
Tardieu, François, Pacitti, Esther, Valduriez, Patrick, Pradal, Christophe, Cohen-Boulakia, Sarah, Heidsieck, Gaëtan   +5 more
core  

Antibodies used for spleen phenotyping.

, 2021
Antibodies used for spleen phenotyping.
Meenal Elliott (11383709), Jamie L. McCall (6194741), John B. Barnett (11383712), Kathryn E. Blethen (11383703), Casey Hall (11383706), Harry C. Blair (9341889)   +5 more
core   +1 more source