Results 61 to 70 of about 194,178 (304)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
International Mouse Phenotyping Consortium IMPC. Behavior and Sensory WG
, 2023 IMPC-Behavior and Sensory WG overview, pipeline. Challenges. Behavioral procedures, number of mouse lines and WG publications. Schizophrenia-associated genes. Genes involved in anxiety behavior.
Sabine Hoelter +2 more
core
A phlorotannin constituent of Ecklonia cava alleviates postprandial hyperglycemia in diabetic mice
Pharmaceutical Biology, 2017 Context: 2,7″-Phloroglucinol-6,6′-bieckol is a type of phlorotannin isolated from brown algae, Ecklonia cava Kjellman (Phaeophyceae; Laminareaceae). 2,7″-Phloroglucinol-6,6′-bieckol mediates antioxidant activities.
Hyun-Ah Lee, Ji-Hyeok Lee, Ji-Sook Han
doaj +1 more source
Remote Sensing, 2021 Optical sensors have been widely reported to be useful tools to assess biomass, nutrition, and water status in several crops. However, the use of these sensors could be affected by the time of day and sky conditions.
Romina de Souza +5 more
doaj +1 more source
Current Opinion in Hematology, 2012 Although recorded evidence of phenotyping bleeding disorders extends back two millennia, standardization of phenotyping has only begun in the past half century. This was spurred by the need for greater precision in diagnosing disorders in order to select proper laboratory tests and treatment, and the realization that the bleeding history provides ...
Paula, James, Barry S, Coller
openaire +2 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
UAV- and Random-Forest-AdaBoost (RFA)-Based Estimation of Rice Plant Traits
Agronomy, 2021 Rapid, accurate and inexpensive methods are required to analyze plant traits throughout all crop growth stages for plant phenotyping. Few studies have comprehensively evaluated plant traits from multispectral cameras onboard UAV platforms.
Farrah Melissa Muharam +8 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
"In-vivo" phenotyping of CYP3A using midazolam as probe drug : development of novel approaches based on highly sensitive LC-MS/MS methods [PDF]
, 2011 Cytochrome P450 (CYP) 3A is the most important subfamily of drug-metabolizing enzymes in humans, responsible for metabolizing more than 50% of the currently marketed drugs.
Link, Bettina
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source