Results 41 to 50 of about 205,158 (302)

Maize Tassel Detection From UAV Imagery Using Deep Learning

open access: yesFrontiers in Robotics and AI, 2021
The timing of flowering plays a critical role in determining the productivity of agricultural crops. If the crops flower too early, the crop would mature before the end of the growing season, losing the opportunity to capture and use large amounts of ...
Aziza Alzadjali   +7 more
doaj   +1 more source

Phenotypic cliffs in the RNA genotype–phenotype map

open access: yesJournal of the Royal Society Interface
Abstract Point mutations of a genotype can leave the phenotype unchanged, or change it, in some cases radically. The extent of this phenotypic change can critically impact fitness. To investigate the range of possible phenotypic changes that result from point mutations, we analyse the structure of the well-established RNA genotype ...
Paula García-Galindo, Sebastian Ahnert
openaire   +3 more sources

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz   +12 more
wiley   +1 more source

What is cost-efficient phenotyping? Optimizing costs for different scenarios [PDF]

open access: yes, 2019
Progress in remote sensing and robotic technologies decreases the hardware costs of phenotyping. Here, we first review cost-effective imaging devices and environmental sensors, and present a trade-off between investment and manpower costs.
Bostrom, Aaron   +27 more
core   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman   +9 more
wiley   +1 more source

Insight Report: Online public involvement session on the views of patients living with Inflammatory Bowel Disease (IBD) in relation to a Multiomic phenotyping of IBD. [PDF]

open access: yes, 2022
A report summarising the insights of patients living with IBD about an Imperial BRC research project involving Multiomic phenotyping of ...
Perry, robert   +2 more
core   +1 more source

Activin E is a new guardian protecting against hepatic steatosis via inhibiting lipolysis in white adipose tissue

open access: yesExperimental and Molecular Medicine
Hepatic endoplasmic reticulum (ER) stress is implicated in the development of steatosis and its progression to nonalcoholic steatohepatitis (NASH). The ER in the liver can sustain metabolic function by activating defense mechanisms that delay or prevent ...
Shi-Young Park   +11 more
doaj   +1 more source

The Universal Phenotype

open access: yes, 2019
Organisms. Journal of Biological Sciences, V. 3, N. 2 (2019)
Alessio Martino   +2 more
openaire   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine   +21 more
wiley   +1 more source

Analysis of Shoot Architecture Traits in Edamame Reveals Potential Strategies to Improve Harvest Efficiency

open access: yesFrontiers in Plant Science, 2021
Edamame is a type of green, vegetable soybean and improving shoot architecture traits for edamame is important for breeding of high-yield varieties by decreasing potential loss due to harvesting.
Kshitiz Dhakal   +4 more
doaj   +1 more source

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