Results 51 to 60 of about 194,178 (304)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.Carla Ríos Arceo, Jarno Drostwiley +1 more sourceLarge-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous system. [PDF]
, 2012 Cln3(Δex7/8) mice harbor the most common genetic defect causing juvenile neuronal ceroid lipofuscinosis (JNCL), an autosomal recessive disease involving seizures, visual, motor and cognitive decline, and premature death.Boustany, Rose-Mary, Ruether Klaus, Martin Klingenspor, Brown, D., Hölter, S.M., Wheeler, V., Staropoli, J., Schrewe, A., Patricia Da Silva-Buttkus, Dirk H. Busch (125319), Ella Dragileva, Martin Hrabě de Angelis, Wolfgang Wurst (712), Wurst, Wolfgang, Raffi Bekeredjian (160215), Jolene Guide, de Angelis, M., Klingenspor Martin, Klopstock, T., Rathkolb, B., Harati, Hayat, Graw Jochen, Harati Hayat, Breton, Sylvie, Wolf Eckhard, Oliver Puk (160194), Frauke Neff, Calzada-Wack, Julia, Jan Rozman, Hrabé de Angelis, Martin, Larissa Haliw (160166), Calzada-Wack, J., Staropoli, J.F., Anja Schrewe, Cotman, S., Garrett, L., Busch, D. H., Julia Calzada-Wack (160181), Klingenspor, Martin, John F Staropoli, Lillian Garrett (160169), Garrett Lillian, Biswas Sunita, Lopez, E., Sun, M., Favor, J., Rose-Mary Boustany (160261), Gale Evan, Hölter, S., Racz, I., Ildikó Racz (5649520), Hill, Eric, Birgit Rathkolb, Klopstock, Thomas, Fuchs, Helmut, Biswas, Sunita, Eckhard Wolf, Krause, D., Fuchs Helmut, Ruether, Klaus, Thure Adler (125314), Busch, D.H., Cotman, S.L., Krause, D.S., Brown, D.E., Busch, D., Klaus Ruether, Raffi Bekeredjian, Jack Favor, Jan Rozman (149181), Hayat Harati (160240), Racz, Ildikó, Anja Schrewe (160188), Evan Gale (160257), Boustany, R., Biswas, S., Fuchs, H., Neff Frauke, Martin Hrabě de Angelis (2579524), Birgit Rathkolb (39867), Haliw, L., Valérie Gailus-Durner, Dragileva Ella, Lillian Garrett, Da Silva-Buttkus Patricia, Daniela S Krause, Helmut Fuchs, Skosyrski, Sergej, Daniela S. Krause (160249), Hill, E., Staropoli John F., Andreas Zimmer (78836), Boustany Rose-Mary, Favor Jack, Patricia Da Silva-Buttkus (160178), Cotman, Susan L., Breton Sylvie, Krause, D. S., Dragileva, Ella, Andreas Zimmer, Thomas Klopstock (160225), Sun Minxuan, Becker, Lore, Sergej Skosyrski, Helmut Fuchs (39863), Hölter, Sabine M., Klaus Ruether (160274), Brown, Diane E., Zimmer Andreas, Hill Eric, Oliver Puk, Da Silva-Buttkus, P., de Angelis Martin Hrabě, Gailus-Durner Valérie, Wolf, Eckhard, Becker Lore, Larissa Haliw, Gale, Evan, Sylvie Breton (160269), Staropoli, J. F., Minxuan Sun (160200), Evan Gale, Zimmer, Andreas, Hrabě de Angelis, M., Sabine M Hölter, Boustany, R. M., Adler, Thure, de Angelis, M. H., Favor, Jack, Racz Ildikó, Jack Favor (160206), Ildikó Racz, Klopstock Thomas, Hölter, S. M., Wurst, W., Jolene Guide (160252), Guide, Jolene, Sun, Minxuan, Gailus-Durner, Valérie, Wolf, E., Brown, D. E., Becker, L., Lore Becker (160172), Guide Jolene, Neff, F., Eric Hill (160245), Sabine M. Hölter (160170), Vanessa C Wheeler, Skosyrski, S., Cotman Susan L., Lopez Edith, Busch, Dirk H., Sunita Biswas (160168), Staropoli, John F., Garrett, Lillian, Julia Calzada-Wack, Wheeler, V.C., Puk, Oliver, Krause, Daniela S., Sun, M. X., Graw, Jochen, Jochen Graw (47527), Haliw, Larissa, Lore Becker, Valérie Gailus-Durner (125329), Schrewe, Anja, Ella Dragileva (136558), Edith Lopez, Brown Diane E., Bekeredjian, R., Wolfgang Wurst, Hölter Sabine M., Puk Oliver, Neff, Frauke, Da Silva-Buttkus, Patricia, Bekeredjian, Raffi, Puk, O., Thure Adler, Thomas Klopstock, Minxuan Sun, Wheeler Vanessa C., Busch Dirk H., Jochen Graw, Wheeler, Vanessa C., Frauke Neff (160183), Wheeler, V. C., Rathkolb, Birgit, Edith Lopez (160236), Bekeredjian Raffi, Rozman, J., Rozman, Jan, Boustany, R.M., Haliw Larissa, Susan L Cotman, Susan L. Cotman (160284), Ruether, K., Harati, H., Diane E. Brown (160264), Rose-Mary Boustany, Graw, J., Sunita Biswas, Sergej Skosyrski (160175), Schrewe Anja, Dragileva, E., Gailus-Durner, V., Sylvie Breton, Eric Hill, Adler Thure, Skosyrski Sergej, Eckhard Wolf (39870), John F. Staropoli (160164), Dirk H Busch, Wurst Wolfgang, Krause Daniela S., Lopez, Edith, Martin Klingenspor (68144), Zimmer, A., Klingenspor, M., Diane E Brown, Rathkolb Birgit, Guide, J., Adler, T., Gale, E., Hayat Harati, Calzada-Wack Julia, Breton, S., Rozman Jan, Cotman, S. L., Vanessa C. Wheeler (136566), Silva-Buttkus, Patricia da +229 morecore +2 more sourcesRapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength [PDF]
, 2012 Osteoporosis is a common polygenic disease and global healthcare priority but its genetic basis remains largely unknown. We report a high-throughput multi-parameter phenotype screen to identify functionally significant skeletal phenotypes in mice ...Gogakos Apostolos, Campbell, MJ, Anne H. van der Spek (145990), Campbell Michael J., Gogakos, A, Sunter, D, Williams, GR, David Sunter, Bassett, JHD, Boyde, A, Michael J. Campbell (5833), Sunter, D., Richard M Jacques, Project, S.M.G., Alan Boyde (146008), Croucher Peter I., Ramirez-Solis, R, Williams, G.R., Richard M. Jacques (145985), van der Spek Anne H., Holly Evans (145980), Bassett, J.H.D., Ryder, E, Edward Ryder (145998), Peter I. Croucher (146016), Graham R Williams, Evans, H, Bassett J. H. Duncan, Jacques, RM, Anne H van der Spek, J. H. Duncan Bassett (145971), Croucher, PI, Peter I Croucher, Project, SMG, Ryder, E., David Sunter (146002), Holly Evans, Gogakos, A., Jacqueline K. White (119191), Apostolos Gogakos (145975), Ramirez-Solis, R., Jacqueline K White, White Jacqueline K., Boyde, A., van der Spek, A.H., Evans, H., Michael J Campbell, Ramirez-Solis Ramiro, White, J.K., Jacques, R.M., J H Duncan Bassett, Apostolos Gogakos, Jacques Richard M., Croucher, P.I., Ryder Edward, Graham R. Williams (20148), Campbell, M.J., Evans Holly, Ramiro Ramirez-Solis (119181), Williams Graham R., Ramiro Ramirez-Solis, Edward Ryder, Alan Boyde, van der Spek, AH, Sanger Mouse Genetics Project, Sunter David, White, JK, Boyde Alan +67 morecore +1 more sourceDeepCount: In-Field Automatic Quantification of Wheat Spikes Using Simple Linear Iterative Clustering and Deep Convolutional Neural Networks
Frontiers in Plant Science, 2019 Crop yield is an essential measure for breeders, researchers, and farmers and is composed of and may be calculated by the number of ears per square meter, grains per ear, and thousand grain weight. Manual wheat ear counting, required in breeding programs Pouria Sadeghi-Tehran, Nicolas Virlet, Eva M. Ampe, Piet Reyns, Malcolm J. Hawkesford +4 moredoaj +1 more sourceDiversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.Ilaria Chiaradia, Madeline A. Lancasterwiley +1 more source