Results 211 to 220 of about 137,373 (269)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Establishing Reference Intervals for White Blood Cell and Absolute Neutrophil Counts in Duffy Null Individuals. [PDF]

Hematol Rep
Barouqa M, Ashfaq MA, Jiang KJ, Kilic H, Dela Cruz N, Khalid A, Yassa ME.   +6 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

SHREC: A framework for advancing next-generation computational phenotyping with large language models. [PDF]

PLOS Digit Health
Pungitore S, Yadav S, Douglas M, Mosier J, Subbian V.   +4 more
europepmc   +1 more source

Personalized Diabetes Therapy Part 1-Functional Phenotyping as a Conceptual Basis for Individualized Treatment. [PDF]

J Pers Med
Pfützner A, Jantz J.
europepmc   +1 more source

Negative symptoms in schizophrenia: Methodological challenges and emerging solutions for outcome measurement. [PDF]

Neurosci Appl
Mucci A, Davidson M, Zaragoza Domingo S, Alphs L, Bitter I, Cohen A, Dorffner G, Fernandez-Egea E, Leucht S, Ochoa S, Reininghaus E, Galderisi S.   +11 more
europepmc   +1 more source

Artificial Intelligence-Based Risk Stratification in Obesity Care: From Diagnosis to Personalised Treatment Pathways. [PDF]

Diagnostics (Basel)
Wójcik S, Tomaszewska M, Rulkiewicz A.
europepmc   +1 more source

Using AI to Detect Psychosis Relapse: Scoping Review. [PDF]

JMIR Ment Health
Ghelfi L, Healy J, Piacenza F, French I, McNamara N, Rabbi KA, Bond B, O'Hora E, Roddy D, Kamali M, Das S, Just SA, Tedeschi E, Hussain M, Mikalsen KØ, Kaiser S, Cecere G, Koops S, de Boer J, Nguyen E, Bora E, Hinzen W, Homan P, Sommer IE, Cotter D, Cannon M, Lyne JP.   +26 more
europepmc   +1 more source

Author Response: From Descriptive Hemodynamics to Decision-grade Vasoplegia Phenotyping: The Next Translational Step for Temporal Diastolic Shock Index. [PDF]

Indian J Crit Care Med
Sarkar S, Azim A.
europepmc   +1 more source