Results 251 to 260 of about 1,168,358 (338)

Challenges and approaches to calibrating patient phenotype as evidence for cancer gene variant classification under ACMG/AMP guidelines [PDF]

Cristina Fortuño, Kyriaki Michailidou, Michael T. Parsons, Jill S. Dolinsky, Tina Pesaran, Amal Yussuf, Jessica L. Mester, Kathleen S. Hruska, Susan Hiraki, Robert O’Connor, Raymond C. Chan, Serra Kim, Sean V. Tavtigian, David E. Goldgar, Paul A. James, Amanda B. Spurdle   +15 more
openalex   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Understanding the genetics of root system architecture in pigeonpea [Cajanus cajan (L.) Millsp.]. [PDF]

Theor Appl Genet
Gaiwal KB, Belliappa SH, Bomma N, Naik S, Sandhyakishore N, Rangari SK, Kalyan A, Mehtre SP, Vemula A, Bhosale R, Pandey MK, Gandhi H, Mayes S, Gangashetty PI.   +13 more
europepmc   +1 more source

Behavioural phenotyping assays for mouse models of autism

Nature Reviews Neuroscience, 2010
J. Silverman, Mu Yang, C. Lord, J. Crawley   +3 more
semanticscholar   +1 more source

CD56neg CD16+ cells represent a distinct mature NK cell subset with altered phenotype and are associated with adverse clinical outcome upon expansion in AML [PDF]

Julia Wlosik, Florence Orlanducci, Manon Richaud, Clémence Demerle, Amira Ben Amara, Marie-Sarah Rouviére, Philippe Livrati, Laurent Gorvel, Marie‐Anne Hospital, Nicolas Dulphy, Raynier Devillier, Norbert Vey, Daniel Olive   +12 more
openalex   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Comprehensive analysis of two hotspot codons in the TUBB4B gene and associated phenotypes [PDF]

Jan-Philipp Bodenbender, Valerio Marino, Julia Philipp, Anke Tropitzsch, Christoph Kernstock, Katarína Štingl, Melanie Kempf, Tobias B. Haack, Theresia Zuleger, Pascale Mazzola, Susanne Kohl, Nicole Weisschuh, Daniele Dell’Orco, Laura Kühlewein   +13 more
openalex   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Quantitative dissection of sexual dimorphism in mice through Y-linked gene knockouts and multivariate phenotyping. [PDF]

Sci Rep
Tanaka N, Miura K, Ozaki A, Kozawa Y, Tamura M, Ogura A, Matoba S.   +6 more
europepmc   +1 more source