.: Adult T-cell leukemia (ATL) is a malignant tumor of human CD4+ T cells infected with a human retrovirus, T lymphotropic virus type-1 (HTLV-1). The aim of the present study was to investigate the apoptotic effects of phenoxazines, 2-amino-4,4α-dihydro ...
Naoko Miyano-Kurosaki +7 more
doaj +1 more source
Turbocharged molecular discovery of OLED emitters: from high-throughput quantum simulation to highly efficient TADF devices [PDF]
Discovering new OLED emitters requires many experiments to synthesize candidates and test performance in devices. Large scale computer simulation can greatly speed this search process but the problem remains challenging enough that brute force ...
Aguilera-Iparraguirre, Jorge +7 more
core +1 more source
Organic and Metallacages for Chemical Sensing: Progress in Water‐Compatible Systems
Supramolecular cages function as three‐dimensional receptors for selective molecular recognition and sensing, and this review outlines design principles for water‐stable architectures, key analyte‐ and medium‐dependent challenges, recent water‐compatible examples (including polymer‐integrated systems), and future opportunities for cage‐based ...
Rabia Zahid +4 more
wiley +1 more source
Benzo[a]phenoxazinium chlorides functionalized with chloride atoms and/or ester groups [PDF]
Proceedings of the 19th Int. Electron. Conf. Synth. Org. Chem.With the aim of contributing to the development of fluorescent near-infrared (NIR) probes with applications in biomedicine, our research group is committed to the development of new water ...
Coutinho, Paulo J. G. +4 more
core +1 more source
Synthesis and fluorescence properties of side-chain carboxylated 5,9-diaminobenzo[a]phenoxazinium salts [PDF]
The efficient synthesis of a series of novel side-chain carboxylated 5,9-diaminobenzo[a]phenoxazinium salts is described. The ring system was prepared by the reaction of 5-alkylamino-2-nitrosophenol hydrochlorides with the appropriate N-alkylated ...
Frade, Vânia H. J. +2 more
core +1 more source
Inductive queries for a drug designing robot scientist [PDF]
It is increasingly clear that machine learning algorithms need to be integrated in an iterative scientific discovery loop, in which data is queried repeatedly by means of inductive queries and where the computer provides guidance to the experiments that ...
A. Lingas +10 more
core +1 more source
Intumescent composition, foamed product prepared therewith and process for making same [PDF]
An intumescent composition and the foamed product prepared by heating the composition are provided. The composition comprises the reaction product of para-benzoquinone dioxime and a concentrated mineral acid such as sulfuric acid, phosphoric acid, and ...
Parker, J. A., Riccitiello, S. R.
core +1 more source
We examined the in vivo antiviral activities of 2-amino-4,4α-dihydro-4α-7-dimethyl-3H-phenoxazine-3-one (Phx-1), 3-amino-1,4α-dihydro-4α-8-dimethyl-2H-phenoxazine-2-one (Phx-2), and 2-aminophenoxazine-3-one (Phx-3) against herpes viruses. The virus yield
Kyoko Hayashi +3 more
doaj +1 more source
Glucose-6-phosphate-dehydrogenase deficiency as a risk factor in proliferative disorder development [PDF]
Glucose-6-phosphate dehydrogenase (G6PD) is an important site of metabolic control in the pentose phosphate pathway (PPP) which provides reducing power (NADPH) and pentose phosphates.
Alessandra Pani +9 more
core +1 more source
Photophysical and structural properties of the fluorescent nucleobase analogues of the tricyclic cytosine (tC) family [PDF]
Fundamental insight into the unique fluorescence and nucleobase-mimicking properties of the fluorescent nucleobase analogues of the tC family is not only vital in explaining the behaviour of these probes in nucleic acid environments, but will also be ...
Albinsson, Bo +3 more
core +1 more source

