Effect of High-Pressure Processed Apples on Phenolic Metabolites, Short-Chain Fatty Acids, and Human Gut Microbiota Using a Dynamic In Vitro Colonic Fermentation System. [PDF]
Metabolitesde Ancos B +4 more
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Sodium thiosulfate-catalysed synthesis of thioethers from aldehydes or carboxylic acids. [PDF]
R Soc Open SciSalehi M, Nowrouzi N, Abbasi M.
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Characterization of a Silver Vinylcarbene Intermediate in Carbene-Alkyne Metathesis and Its Concerted C(sp2)-H Bond Insertion. [PDF]
J Am Chem SocDíaz-Jiménez À +10 more
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<i>Flagellimonas ulvae</i> sp. nov. and <i>Flagellimonas rhodophyticola</i> sp. nov., isolated from marine algae. [PDF]
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AbstractNatural phenethyl acetate (PEA), phenylacetic acid (PAA), ethyl phenylacetate (Et‐PA), and phenethyl phenylacetate (PE‐PA) are highly desirable aroma chemicals, but with limited availability and high price. Here, green, sustainable, and efficient bioproduction of these chemicals as natural products from renewable feedstocks was developed.
Balaji Sundara Sekar, Xirui Li, Zhi Li
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Phenylacetic acid excretion in man
Analytical Biochemistry, 1979A rapid, reliable, sensitive, and highly specific mass fragmentographic method for the quantification of phenylacetic acid (PAA) in urine is described. The method was used to determine total, conjugated, and free PAA simultaneously in normal urine. The mean ± SE excretion of total, conjugated, and free PAA in urine of 24 normal adult volunteers were ...
M E, Martin, F, Karoum, R J, Wyatt
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Dissociation constants of phenylacetic acid and three substituted phenylacetic acids
Journal of the Chemical Society B: Physical Organic, 1971The dissociation constants of four acids in aqueous solution have been determined at 25° by means of conductivity measurements. The pK values are: phenylacetic acid, 4·310; o-methylphenylacetic acid, 4·297; o-ethylphenylacetic acid, 4·317; o-fluorophenylacetic acid, 4·093.
Wayne C. Duer, R. A. Robinson
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Phenylacetic acid derivatives as hPPAR agonists
Bioorganic & Medicinal Chemistry Letters, 2003Beginning with the weakly active lead structure 1, a new series of hPPAR agonists was developed. In vivo glucose and triglyceride lowering activity was obtained by homologation and oxamination to 3, then conversion to substituted benzisoxazoles 4 and 5. Further manipulation afforded benzofurans 6 and 7. Compound 7 was of comparable potency as a glucose
Conrad, Santini +10 more
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Acid Strengths of the Phenylacetic Acids
Journal of The Electrochemical Society, 1953The ratio of dissociation constants Ksubstituted acid/Kacetic acid was determined in methanol and ethanol for mono‐, di‐, and triphenylacetic acid by the electrometric and colorimetric methods. In water, the insolubility of triphenylacetic made another procedure necessary with that acid, and the solubility method of Lowenherz was employed.
Mary L. Kilpatrick, Edward Fackenthal
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Shunting Phenylacetic Acid Catabolism for Tropone Biosynthesis
ACS Synthetic Biology, 2019Tropone is a seven-membered ring nonbenzenoid aromatic compound. It is the core structure of tropolonoids, which have various biological activities. In this study, a hybrid tropone biosynthetic pathway was designed by connecting phenylacetic acid (PAA) degradation with its biosynthesis and reconstituted in Escherichia coli.
Yan Li +7 more
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