Results 91 to 100 of about 232,397 (303)

Conversion of D-phenylalanine to L-phenylalanine in humans.

open access: yesNippon Eiyo Shokuryo Gakkaishi, 1988
健康な女子2名にD-Phe-d5を8mg/kg体重, 他の必須アミノ酸および低タンパク質食とともに経口負荷し, 1, 4, 8時間後に採血した。血漿中の遊離フェニルアラニンをHPLCによりDL分割し, L画分について, Phe-d5/Phe-d0モル比をGC-MS-MIDにより測定した。この結果から, 血漿中のD-Phe-d5および, これから変換したL-Phe-d5の量を, 血漿中に天然に存在しているL-Phe-d0とのモル比として算出した。負荷後の血漿中のD-Phe-d5/L-Phe-d0モル比の最低は負荷1時間後の0.38 (被験者S: 0.16, T: 0.60の平均値), 最高は負荷4時間後の0.78 (S: 0.72, T: 0.84) であった。-Phe-d5/L-Phe ...
SAISU, Kumiyo   +2 more
openaire   +2 more sources

Combining Fret and Super‐Resolution Microscopy Reveals Kinase Activation and Mitochondrial Activity at the Nanoscale

open access: yesAdvanced Science, EarlyView.
BioSenSRRF is an open‐source workflow that combines conventional FRET biosensors with SRRF reconstruction to generate sub‐diffraction FRET index maps on standard microscopes. The pipeline integrates automated image registration, SRRF reconstruction, quantitative FRET index calculation, and random line‐based hotspot analysis to uncover AURKA‐dependent ...
Nicolas Y. Jolivet   +5 more
wiley   +1 more source

Results of a Prospective Study Concerning the Clinical Efficiency of Recent Russian-Made Specialized Foods without Phenylalanine

open access: yesПедиатрическая фармакология, 2016
Background: Specialized foods, based on aminoacids without phenilalanin, are the main source of protein for patients with phenilketonuria of all ages. Based on modern technologies, new Russian-made foods were created. They have an optimized aminoacid and
T. V. Bushueva   +3 more
doaj   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

open access: yesAdvanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou   +10 more
wiley   +1 more source

Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils

open access: yesAdvanced Science, EarlyView.
We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr   +19 more
wiley   +1 more source

Role of phenylalanine in viticulture and enology

open access: yes, 2015
Total nitrogen in grapes consists of inorganic and organic forms. Ammonia salts and amino acids are the most prevalent form of total nitrogen by weight in grapes.
González-Arenzana, L. [0000-0001-5181-3173]   +6 more
core  

Evaluation of Taste and Hypoglycemic Activities of Phenylalanine Derivatives by Introducing Various Organic Compounds [PDF]

open access: yes, 1991
L体およびD体のフェニルアラニンのN端に種々有機酸を導入した誘導体,およびC端にアルコールおよびアミンを導入した誘導体を合成した。合成した全サンプルについて,中間生成物を含めて呈味試験を行なったが,目的とする甘味あるいは塩から味は得られず,苦味あるいは酸味のものがほとんどだった。 さらにその一部について,ラットを用いた経口投与での血糖値抑制効果を測定したが,Perilloyl-Phe-OMe, Z-Val-Gly-OH及びBoc-Phe-D-Glucosamineのいずれからも,むしろ ...
池辺, 裕行   +5 more
core  

Phenylalanine iminoboronates as new phenylalanine hydroxylase modulators

open access: yesRSC Adv., 2014
Herein we report the discovery of new modulators of human phenylalanine hydroxylase (hPAH) inspired by the structure of its substrate and regulatorl-phenylalanine.
Francesco Montalbano   +7 more
openaire   +1 more source

Chitosan‐Carbon Dot Composite Materials Form a Leaf Surface Barrier to Mitigate the Enrichment and Invasion of Nanoplastics: From Leaf Interface to Systemic Response

open access: yesAdvanced Science, EarlyView.
Foliar spraying of CS‐CDs can form a film on the leaves of Brassica rapa, effectively reducing the enrichment and absorption of PS in the leaves, while increasing the biomass and nutrient content of the plants. In addition, CS‐CDs can also enrich the interfoliar microbial community and activate the plant's own defense metabolic pathways.
Beibei Zhao   +6 more
wiley   +1 more source

Multistep Enzymatic Low-density Polyethylene Degradation via Phenylalanine Monooxygenase and Isocitrate Lyase in Pseudomonas aeruginosa

open access: yes
Plastics have become indispensable in modern industries; however, their resistance to natural degradation poses environmental challenges. Biological degradation technologies employing microorganisms offer promising solutions.
Donggeun, Choi   +4 more
core   +1 more source

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