Results 71 to 80 of about 254,425 (304)

phenylalanine metabolism-html

, 2014
unigenes associated with phenylalanine ...
Karen Fugate (480954)
core   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Chemical structures of aspartame (A), α-L-aspartyl-D-phenylalanine methyl ester (L, D-APM) (B), α-D-aspartyl-L-phenylalanine methyl ester (D, L-APM) (C), and α-D-aspartyl-D-phenylalanine methyl ester (D, D-APM) (D).

, 2016
Chemical structures of aspartame (A), α-L-aspartyl-D-phenylalanine methyl ester (L, D-APM) (B), α-D-aspartyl-L-phenylalanine methyl ester (D, L-APM) (C), and α-D-aspartyl-D-phenylalanine methyl ester (D, D-APM) (D).
Mika Yoshida (55699), Ryoichiro Nakamura (2576425), Hiroshi Akiyama (825948), Yoko Oobayashi (2576434), Akira Otabe (2576419), Mitsuya Yoshida (2576422), Kyoko Sato (720528), Takashi Ohtsuki (8811), Shoko Suzuki (793696), Chiye Tatebe (2576428), Satoru Kubo (2576431)   +10 more
core   +1 more source

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source

EVALUATION OF PHENYLALANINE ISOTOPES USING AN ISOLATED ORGAN PERFUSION MODEL [PDF]

, 1999
The objective of the research was to evaluate the possibility of isotopic discrimination between two isotopomers of phenylalanine during the hydroxylation to tyrosine.
Lordon, Carolyn D.
core  

phenylalanine metabolism-png

, 2014
unigenes associated with phenylalanine ...
Karen Fugate (480954)
core   +1 more source

NiH‐Catalyzed Enantio‐ and Regioselective Hydroselenylation of Unactivated Alkenes

Advanced Science, EarlyView.
Nickel‐hydride‐catalyzed enantio‐ and regioselective hydroselenylation of unactivated alkenes provides access to chiral organoselenium compounds. Enantiodetermining Ni–H insertion followed by single‐electron diselenide activation generates selenyl radical.
Hyung‐Joon Kang, Jaehun Kim, Sungwoo Hong   +2 more
wiley   +1 more source

Phenylalanine-based low-molecular-weight gelator for the removal of metal ions and dyes from wastewater

, 2019
Increasing water pollution is a major concern for the global community. So, purification and reuse of wastewater are very much urgent. In this work, methyl ester of phenylalanine (Phe-OMe), a non-gelator, has been successfully applied to produce two ...
Mrittika Mohar (6565322), Tanmay Das (4520710)   +1 more
core   +1 more source

The Landscape of Long Non‐Coding RNAs Provides Insights Into the Domestication and Improvement of Pear Fruit

Advanced Science, EarlyView.
This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song, Peilin Han, Jiaming Li, Xiaolong Li, Xiang Zhang, Jing Fan, Dongliang Liu, Jianfa Cai, Lingchao Zhang, Jun Wu   +9 more
wiley   +1 more source

Extensive Dysregulation of Phenylalanine Metabolism Is Associated With Stress Hyperphenylalaninemia and 30‐Day Death in Critically Ill Patients With Acute Decompensated Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Stress hyperphenylalaninemia predicts elevated mortality rates in patients with acute decompensated heart failure (ADHF). This study investigated the metabolic pathways underlying this association and identified a unique metabolic phenotype ...
Wei‐Siang Chen, Min‐Hui Liu, Yi‐Liang Tsou, Huang‐Ping Wu, Hsuan‐Ching Lin, Chung‐Yu Liang, Chao‐Hung Wang   +6 more
doaj   +1 more source