Results 141 to 150 of about 359,480 (360)

Reversible Lichtinduzierte Oligomerisierung von Arabidopsis‑Cryptochrom 1 und Antagonismus durch BIC1: Einblicke durch Zeitaufgelöste Native Massenspektrometrie

Angewandte Chemie, EarlyView.
Mittels zeitaufgelöster nativer Massenspektrometrie wird der blaulichtabhängige kinetische Mechanismus der Oligomerisierung von Arabidopsis CRY1 aufgedeckt. Die Oligomerisierung verläuft sequenziell von Monomeren über Dimere zu Tetrameren. Während ATP die Assemblierung fördert, inhibiert BIC1 die Tetramerbildung und dissoziiert diese unabhängig von ...
Alicia Just, Nils Niemann, Petra Gnau, Dennis Kock, Thomas Heimerl, Stephan Kiontke, Lars‐Oliver Essen, Alfred Batschauer, Nina Morgner   +8 more
wiley   +1 more source

Do early‐treated adults with phenylketonuria sense high phenylalanine levels?

JIMD Reports
This study aimed to analyze whether early‐treated adults with phenylketonuria (PKU) can subjectively sense high phenylalanine (Phe) concentrations and whether a possible impact of Phe on objective measures of cognitive performance and mood reflects ...
Laura Hauri, Raphaela Muri, Regula Everts, Roman Trepp   +3 more
doaj   +1 more source

O‐Terphenyl‐basierte Familie konjugierter Makrozyklen: Selektive Erkennung von Phenylalanin im Wasser und Interaktion mit Insulin

Angewandte Chemie, EarlyView.
Diese Studie beschreibt die Herstellung und Eigenschaften einer neuen Familie von o‐Terphenyl‐basierten Makrozyklen, TP[n] (n = 2‐8). Der Trimer bindet Phenylalanin in Wasser sehr effizient und ist dabei zehnmal selektiver als bei anderen Aminosäuren und aromatischen Neurotransmittern.
Swapnil Ghule, Sayan Sarkar, Maria Eugenia Pérez‐Ojeda Rodriguez, Mark Spector, Frank Hampel, Evgeny A. Kataev   +5 more
wiley   +1 more source

Activation of the phosphosignaling protein CheY. I. Analysis of the phosphorylated conformation by 19F NMR and protein engineering [PDF]

, 1993
CheY, the 14-kDa response regulator protein of the Escherichia coli chemotaxis pathway, is activated by phosphorylation of Asp57. In order to probe the structural changes associated with activation, an approach which combines 19F NMR, protein engineering,
Bourret, Robert B., Drake, Steven K., Falke, Joseph J., Luck, Linda A., Simon, Melvin I.   +4 more
core  

Purification and characterization of a dimeric phenylalanine dehydrogenase from Rhodococcus maris K-18

, 1989
H. Misono, J Yonezawa, Shigekazu Nagata, S. Nagasaki   +3 more
openalex   +2 more sources

Phenylalanine Stimulation of Gramicidin S Formation

, 1976
Arnold L. Demain, Charles C. Matteo
openalex   +2 more sources

Comparison of the [2H5]Phenylalanine Model with the [1-13C]Leucine Method to Determine Whole Body Protein Synthesis and Degradation in Sheep Fed at Two Levels [PDF]

, 2007
Mohammad Al-Mamun, Chikako Ito, Atsushi Sato, T Fujita, Hiroaki Sano   +4 more
openalex   +1 more source

Genome-wide analysis of phenylalanine ammonia-lyase (PAL) gene family in five Rosaceae plants and expression analysis and functional identification of Chinese white pear

, 2019
Hui Guo Li, Han Wang, Xi Cheng, Qiang Xue Su, Yu Zhao, Shan Tao Jiang, Qin Jin, Yi Lin, Ping Yong Cai   +8 more
openalex   +1 more source

Bicyclic Pyrrolidine Inhibitors of Toxoplasma gondii Phenylalanine t-RNA Synthetase with Antiparasitic Potency In Vitro and Brain Exposure [PDF]

Chloe C. Ence, Taher Uddin, Julien Borrel, Payal Mittal, Han Xie, Jochen Zoller, Amit Sharma, Eamon Comer, Stuart L. Schreiber, Bruno Melillo, L. David Sibley, Arnab K. Chatterjee   +11 more
openalex   +1 more source

Nano‐Gs Protein Peptidomimetics: Rational Design of Gα C‐Terminus‐Derived Peptides Mimicking Key Components of Gs‐β2AR Interactions

Angewandte Chemie International Edition, EarlyView.
G protein‐coupled receptors (GPCRs) are major therapeutic targets. Modulating GPCR activity through intracellular sites is evolving. A structure‐ and computation‐assisted approach generated small G protein‐derived peptidomimetics targeting the intracellular binding crevice of the β2 adrenergic receptor mimicking features of the full G protein.
Phuong Thu Tran, Mia Danielsen, Johanna K. S. Tiemann, Passainte Ibrahim, Søren G. F. Rasmussen, Xavier Kubiak, Hossein Batebi, Charlène Gadais, Steven Ballet, Peter W. Hildebrand, Daniel Sejer Pedersen, Jesper Mosolff Mathiesen   +11 more
wiley   +1 more source