Results 181 to 190 of about 359,480 (360)

Engineering of CoA‐Acylating Butyraldehyde Dehydrogenase for Enhanced 1,3‐Butanediol Production in Escherichia coli

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Microbial production of 1,3‐butanediol (1,3‐BDO) offers a renewable route to this versatile C4 chemical. However, the low performance of CoA‐acylating butyraldehyde dehydrogenase (Bld), which contains a catalytic cysteine, limits efficient production in recombinant Escherichia coli (E. coli).
Seunghyun Cho   +5 more
wiley   +1 more source

Genetic code expansion for chemosensing and chemical actuation of biological functions

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Genetic code expansion (GCE) broadens the chemical repertoire for precise control of protein function in biological systems. This review highlights GCE‐based sensing and actuating systems that operate through selective interactions between noncanonical amino acids and chemical triggers.
Jieun Bae, Dong‐Hyun Kim, Minseob Koh
wiley   +1 more source

Two adult sisters with untreated phenylketonuria: Strikingly discordant clinical phenotype. [PDF]

open access: yesMol Genet Metab Rep
Demirbas D   +6 more
europepmc   +1 more source

Protein hydrolysates in cell culture: Toward multi‐omics characterization

open access: yesBiotechnology Progress, EarlyView.
While protein hydrolysates are widely used in cell culture applications, they remain undefined and variable products. Multi‐omic characterization evaluating composition and function can transition hydrolysates toward semi‐defined media components.
Michelle Combe   +3 more
wiley   +1 more source

Oral amino acid tracer delivery detects feeding and exercise changes in myofibrillar protein synthesis rates in male adults. [PDF]

open access: yesPhysiol Rep
Mazzulla M   +7 more
europepmc   +1 more source

Formation of mitochondria of locusta migratoria flight muscle [PDF]

open access: yes, 1971
Boardman, N. K.   +6 more
core   +1 more source

Rapid development of a transferable Raman model using high‐throughput cell culture for monitoring monoclonal antibody titer

open access: yesBiotechnology Progress, EarlyView.
Abstract Monoclonal antibody (mAb) titer monitoring is a key capability during process development and optimization, enabling timely decision making and increasing the speed of development. Raman spectroscopy is a prominent process analytical technology (PAT), but resource‐efficient calibration strategies for the development of transferable models are ...
Alexandra Umprecht   +4 more
wiley   +1 more source

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