Results 211 to 220 of about 394,077 (382)

Biochemical and Structural Analysis of Substrate Specificity of a Phenylalanine Ammonia-Lyase1

open access: yesPlant Physiology, 2017
S. Jun   +5 more
semanticscholar   +1 more source

Antiviral effects and mechanism of Qi pi pill against influenza viruses

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Qi pi pill presents anti‐influenza effect and inhibits viral replication in vitro by targeting both the viral RNA replication and the release of new viral particles. Furthermore, QPP modulates the production of proinflammatory cytokines induced by influenza infection in host cells.
Chengcheng Zhang   +10 more
wiley   +1 more source

Chirality Makes or Breaks Chemically Driven Self‐Assembly

open access: yesAngewandte Chemie, EarlyView.
Chirality‐controlled reaction cycles: Reaction cycles are constructed to respond to the chirality (handedness) of an acylating agent. Left‐ and right‐handed aminoacyl phosphate esters modulate the structure, lifetime, and transformation of transient (thio)ester intermediates, enabling control over distinct chemical pathways using molecules that are ...
Lenard Saile   +5 more
wiley   +2 more sources

Cerebrospinal Fluid Metabolome in Central Nervous System Infections: A Study of Diagnostic Accuracy

open access: yesAnnals of Neurology, EarlyView.
Objective To assess the diagnostic accuracy of metabolites in cerebrospinal fluid (CSF) for central nervous system (CNS) infections. Methods Patients were derived from three prospective cohort studies in the Netherlands. All studies included adults suspected of a CNS infection who underwent a diagnostic lumbar puncture.
Steven L. Staal   +7 more
wiley   +1 more source

Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence. [PDF]

open access: yesFront Neurol
Ding L   +8 more
europepmc   +1 more source

Biallelic Variants in the DARS2 Gene as a Novel Cause of Axonal Charcot–Marie–Tooth Disease

open access: yesAnnals of Neurology, EarlyView.
Objective Charcot–Marie–Tooth (CMT) disease is a heterogeneous group of genetic neuropathies, with >90 genes identified. Several aminoacyl‐tRNA synthetases have been linked to CMT. DARS2, encoding the mitochondrial aspartyl‐tRNA synthetase, has been typically associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate ...
Berta Estévez‐Arias   +23 more
wiley   +1 more source

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