Decoding asymptomatic COVID-19 infection and transmission [PDF]
arXiv, 2020 Coronavirus disease 2019 (COVID-19) is a continuously devastating public health and the world economy. One of the major challenges in controlling the COVID-19 outbreak is its asymptomatic infection and transmission, which are elusive and defenseless in most situations. The pathogenicity and virulence of asymptomatic COVID-19 remain mysterious. Based on
arxiv
Dynamic transition from $α$-helices to $β$-sheets in polypeptide superhelices [PDF]
arXiv, 2017 We carried out dynamic force manipulations $in$ $silico$ on a variety of superhelical protein fragments from myosin, chemotaxis receptor, vimentin, fibrin, and phenylalanine zippers that vary in size and topology of their $\alpha$-helical packing.
arxiv
A Combined Density Functional Theory and X-ray Photoelectron Spectroscopy Study of the Aromatic Amino Acids [PDF]
arXiv, 2020 Amino acids are essential to all life. However, our understanding of some aspects of their intrinsic structure, molecular chemistry, and electronic structure is still limited. In particular the nature of amino acids in their crystalline form, often essential to biological and medical processes, faces a lack of knowledge both from experimental and ...
arxiv
The Dynamics and Infrared Spectrocopy of Monomeric and Dimeric Wild Type and Mutant Insulin [PDF]
arXiv, 2020 The infrared spectroscopy and dynamics of -CO labels in wild type and mutant insulin monomer and dimer are characterized from molecular dynamics simulations using validated force fields. It is found that the spectroscopy of monomeric and dimeric forms in the region of the amide-I vibration differs for residues B24-B26 and D24-D26, which are involved in
arxiv
Clinical Chemistry, 1993 Abstract Quantitative determination of plasma phenylalanine (Phe) is essential for the diagnosis of phenylketonuria (PKU) and the control of dietary therapy of PKU patients. We have adapted a spectrophotometric method (Clin Chim Acta 1991;201:95-8) based on phenylalanine dehydrogenase (EC 1.4.1.-) for rapid and accurate determinations of
C Farré, M. A. Vilaseca, F Ramón
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Solvent Sensitivity of Protein Unfolding: Study of Chicken Villin Headpiece Subdomain in Water-Ethanol and Water-DMSO Mixtures [PDF]
arXiv, 2013 In the present work we study and compare unfolding of a small protein, chicken villin headpiece (HP-36) in two different aqueous binary mixtures, namely water-ethanol (EtOH) and water-dimethyl sulphoxide (DMSO). In both the binary mixtures, HP-36 is found to unfold (fully or partially, depending on the mixture) under ambient conditions, that otherwise ...
arxiv
THE UTILIZATION OF THE OPTICAL ISOMERS OF PHENYLALANINE, AND THE PHENYLALANINE REQUIREMENT FOR GROWTH [PDF]
Journal of Biological Chemistry, 1946 William C. Rose, Madelyn Womack
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Action of Phenylalanine Metabolites on Glutamic Acid Decarboxylase and gamma-Aminobutyric Acid---alpha-Ketoglutaric Acid Transaminase in Brain. [PDF]
, 1959 Arne Hanson +5 more
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A Phenylalanine Ammonia Lyase Capacitive Sensor for Phenylalanine Detection
Eurosensors 2023In this paper, an easy-to-use and fast biosensor for phenylalanine quantification in patients affected by phenylketonuria is investigated. The phenylalanine concentration was indirectly estimated through the ammonia released as a by-product of an enzymatic reaction, which was then detected by exploiting an yttria-stabilized zirconia layer deposited ...
Bruno Andò +9 more
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Treatment of Phenylketonuria with a Diet Low in Phenylalanine [PDF]
, 1955 L. I. Woolf +2 more
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