Results 11 to 20 of about 19,588 (240)

In-depth sequence-function characterization reveals multiple paths to enhance phenylalanine ammonia-lyase (PAL) activity [PDF]

, 2021
ABSTRACTPhenylalanine ammonia-lyases (PALs) deaminate L-phenylalanine to trans-cinnamic acid and ammonium and have idespread application in chemo-enzymatic synthesis, agriculture, and medicine. In particular, the PAL from Anabaena variabilis (Trichormus variabilis) has garnered significant attention as the active ingredient in Pegvaliase®, the only FDA-
Vikas D. Trivedi, Todd C. Chappell, Naveen B. Krishna, Anuj Shetty, Gladstone Sigamani, Karishma Mohan, Athreya Ramesh, Pravin Kumar R., Nikhil U. Nair   +8 more
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The phenylalanine ammonia lyase (PAL) gene family shows a gymnosperm-specific lineage [PDF]

BMC Genomics, 2012
AbstractBackgroundPhenylalanine ammonia lyase (PAL) is a key enzyme of the phenylpropanoid pathway that catalyzes the deamination of phenylalanine to trans-cinnamic acid, a precursor for the lignin and flavonoid biosynthetic pathways. To date, PAL genes have been less extensively studied in gymnosperms than in angiosperms.
Ujwal Bagal, Jim Leebens‐Mack, W. Walter Lorenz, Jeffrey F. D. Dean   +3 more
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Phylogenomic analysis of phenylalanine ammonia-lyase (PAL) multigene family and their differential expression analysis in wheat (Triticum aestivum L.) suggested their roles during different stress responses. [PDF]

Front Plant Sci, 2022
Zhan C, Li Y, Li H, Wang M, Gong S, Ma D, Li Y.   +6 more
europepmc   +3 more sources

Relationships between Salicylic Acid Content, Phenylalanine Ammonia-lyase (PAL) Activity, and Resistance of Barley to Aphid Infestation

Journal of Agricultural and Food Chemistry, 2003
It has been suggested that salicylic acid (SA) is a signal in acquired resistance to pathogens in several plants. Also, it has been suggested that infestation of plants causes an increase in the activity of phenylalanine ammonia-lyase (PAL), a key phenolic biosynthesis enzyme.
Mercedes E. Chaman Medina, Sylvia V. Copaja, Víctor H. Argandoña   +2 more
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Biochemical Evaluation of Phenylalanine Ammonia Lyase from Endemic Plant Cyathobasis fruticulosa (Bunge) Aellen. for the Dietary Treatment of Phenylketonuria

Food Technology and Biotechnology, 2016
Enzyme substitution therapy with the phenylalanine ammonia lyase (PAL) is a new approach to the treatment of patients with phenylketonuria (PKU). This enzyme is responsible for the conversion of phenylalanine to trans-cinnamic acid.
Seda Şirin, Selcen Babaoğlu Aydaş, Belma Aslım   +2 more
doaj   +2 more sources

Functional characterization and correlation analysis of phenylalanine ammonia-lyase (PAL) in coumarin biosynthesis from Peucedanum praeruptorum Dunn

Phytochemistry, 2018
Coumarins exhibit many biological activities and are the main specialised metabolites of Peucedanum praeruptorum Dunn, an important plant used in traditional Chinese medicine. In preliminary studies, we cloned several genes involved in coumarin biosynthesis in P. praeruptorum, such as 4-coumarate: CoA ligase (4CL), p-coumaroyl CoA 2'-hydroxylase (C2'H),
Ziwei Sui, Jun Luo, Ruolan Yao, Chuanlong Huang, Yucheng Zhao, Lingyi Kong   +5 more
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Activity of Phenylalanine Ammonia-Lyase (PAL) and Concentrations of Anthocyanins and Phenolics in Developing Strawberry Fruit [PDF]

Journal of the American Society for Horticultural Science, 1991
Studies on regulation of production of phenolics in strawberry (Fragaria X ananassa Duch,) fruit were initiated by monitoring phenylalanine ammonia-lyase (PAL) activity and levels of anthocyanins, flavonoids, tannins, and other soluble phenols throughout fruit ontogeny in `Tillikum'.
Guiwen W. Cheng, Patrick J. Breen
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Transcriptional Regulation of the <i>Phenylalanine Ammonia-Lyase</i> (<i>PAL</i>) Gene Family in Mulberry Under Chitosan-Induced Stress. [PDF]

Plants (Basel)
Rakpenthai A, Watanabe M, Wongkaew A, Nakasathien S.   +3 more
europepmc   +3 more sources

Genome-wide identification and characterization of phenylalanine ammonia-lyase (PAL) gene in Vigna radiata L.

REVISTA DELOS
The synthesis of phenylpropanoids is considered one of the plants' most important assimilatory pathways. In higher plants, the amino acid phenylalanine ammonia lyase (PAL; EC 4.3.1.5) is a substrate of primary and secondary metabolic pathways. This study is novel since PAL genes have not been documented in Vigna radiata (L.) Wilczek.
Marcelo Duarte, Tiago Benedito dos Santos, Diliane Harumi Yaguinuma, Jardel de Oliveira, Luís Gustavo Gomes Lobo, Sílvia Graciele Hülse de Souza, Ceci Castilho Custódio   +6 more
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Phenylalanine ammonia-lyase gene family (PAL): Genome wide characterization and transcriptional expression in jute (Corchorus olitorius)

Journal of Bioscience and Agriculture Research, 2020
Jute is one of the important ligno-cellulose bast fiber crops next to cotton. High lignin content in jute fiber makes hindrances during spinning in the textile industry. Phenylalanine ammonia-lyase (PAL), encoded by multigene family, is the first enzyme in the phenylpropanoid pathway which involved in biosynthesis of different secondary metabolites ...
M. S. Hosain, Rasel Ahmed, Md. Wali Ullah, Ummay Honi, Md. Zablul Tareq, Mohammad Saiful Alam Sarker, Borhan Ahmed, Md. Shahidul Islam   +7 more
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