Results 131 to 140 of about 39,051 (241)

Hepatocyte Transplantation Using the Domino Concept in a Child with Tetrabiopterin Nonresponsive Phenylketonuria

Cell Transplantation, 2012
Phenylketonuria is a metabolic disease caused by phenylalanine hydroxylase deficiency. Treatment is based on a strict natural protein-restricted diet that is associated with the risk of malnutrition and severe psychosocial burden.
X. Stéphenne, F. G. Debray, F. Smets, N. Jazouli, G. Sana, T. Tondreau, R. Menten, P. Goffette, F. Boemer, R. Schoos, S. W. Gersting, M. Najimi, A. C. Muntau, P. Goyens, E. M. Sokal M.D., Ph.D.   +14 more
doaj   +1 more source

Alchemical Design of Pharmacological Chaperones with Higher Affinity for Phenylalanine Hydroxylase. [PDF]

Int J Mol Sci, 2022
Conde-Giménez M, Galano-Frutos JJ, Galiana-Cameo M, Mahía A, Victor BL, Salillas S, Velázquez-Campoy A, Brito RMM, Gálvez JA, Díaz-de-Villegas MD, Sancho J.   +10 more
europepmc   +1 more source

Phenylalanine hydroxylase contributes to serotonin synthesis in mice. [PDF]

FASEB J, 2021
Mordhorst A, Dhandapani P, Matthes S, Mosienko V, Rothe M, Todiras M, Self J, Schunck WH, Schütz A, Bader M, Alenina N.   +10 more
europepmc   +1 more source

Impact of Fluorinated Ionic Liquids on Human Phenylalanine Hydroxylase-A Potential Drug Delivery System. [PDF]

Nanomaterials (Basel), 2022
Alves MMS, Leandro P, Mertens HDT, Pereiro AB, Archer M.   +4 more
europepmc   +1 more source

Comparative transcriptomic and metabolomic analysis reveals mechanisms of selenium-regulated anthocyanin synthesis in waxy maize (Zea mays L.)

Frontiers in Plant Science
Anthocyanins in maize (Zea mays L.) kernels determine the plant’s color and can enhance its resistance. Selenium (Se) significantly impacts plant growth, development, and secondary metabolic regulation.
Guangyu Guo, Guangyu Guo, Yufeng Wang, Baoku Zhang, Haoran Yu, Liang Li, Guanglu Cao, Baicui Chen, Chengxin Li, Fanshan Bu, Song Teng, Qingtao Yu, Mingbo Gao, Baiwen Jiang, Kejun Yang   +14 more
doaj   +1 more source

Manipulation of a cation-π sandwich reveals conformational flexibility in phenylalanine hydroxylase. [PDF]

Biochimie, 2021
Arturo EC, Merkel GW, Hansen MR, Lisowski S, Almeida D, Gupta K, Jaffe EK.   +6 more
europepmc   +1 more source

Melatonin mediates phenolic acids accumulation in barley sprouts under MeJA stress

Frontiers in Nutrition
Phenolic acids are secondary metabolites in higher plants, with antioxidant, anticancer, and anti-aging effects on the human body. Therefore, foods rich in phenolic acids are popular.
Xin Tian, Renjiao Zhang, Zhengfei Yang, Jiangyu Zhu, Weiming Fang, Runqiang Yang, Yongqi Yin   +6 more
doaj   +1 more source

Birth prevalence of phenylalanine hydroxylase deficiency: a systematic literature review and meta-analysis. [PDF]

Orphanet J Rare Dis, 2021
Foreman PK, Margulis AV, Alexander K, Shediac R, Calingaert B, Harding A, Pladevall-Vila M, Landis S.   +7 more
europepmc   +1 more source

Mutations of the phenylalanine hydroxylase gene in patients with phenylketonuria in Shanxi, China

Genetics and Molecular Biology, 2012
The variation in mutations in exons 3, 6, 7, 11 and 12 of the phenylalanine hydroxylase (PAH) gene was investigated in 59 children with phenylketonuria (PKU) and 100 normal children.
Yong-An Zhou, Yun-Xia Ma, Quan-Bin Zhang, Wei-Hua Gao, Jian-Ping Liu, Jian-Ping Yang, Gai-Xiu Zhang, Xiao-Gang Zhang, Liang Yu   +8 more
doaj  

Unravelling the Complex Denaturant and Thermal-Induced Unfolding Equilibria of Human Phenylalanine Hydroxylase. [PDF]

Int J Mol Sci, 2021
Conde-Giménez M, Sancho J.
europepmc   +1 more source