Results 171 to 180 of about 178,348 (314)

The toxic effects of meta‐tyrosine are related to its misincorporation into the proteome and to altered metabolism in cyanobacteria

The FEBS Journal, Volume 292, Issue 20, Page 5439-5456, October 2025.
This study reveals that meta‐tyrosine (m‐Tyr), a nonproteinogenic analog of aromatic amino acids, disrupts protein synthesis and photosynthesis in cyanobacteria by being misincorporated by Phenylalanyl‐tRNA synthetase (PheRS) into essential proteins. Through molecular, biochemical, and proteomic analyses in Synechocystis, the research shows that m‐Tyr ...
Hagit Zer, Roei Matan, David Rasin, Yoram Soroka, Noa Carmi, Hanan Schoffman, Nir Keren, Jörg Nickelsen, Oren Ostersetzer‐Biran   +8 more
wiley   +1 more source

CRISPR/Cas9 generated knockout mice lacking phenylalanine hydroxylase protein as a novel preclinical model for human phenylketonuria. [PDF]

Sci Rep, 2021
Singh K, Cornell CS, Jackson R, Kabiri M, Phipps M, Desai M, Fogle R, Ying X, Anarat-Cappillino G, Geller S, Johnson J, Roberts E, Malley K, Devlin T, DeRiso M, Berthelette P, Zhang YV, Ryan S, Rao S, Thurberg BL, Bangari DS, Kyostio-Moore S.   +21 more
europepmc   +1 more source

Glucagon stimulation of rat hepatic phenylalanine hydroxylase through phosphorylation in vivo.

, 1978
J. Donlon, Seymour Kaufman
openalex   +1 more source

The Pea Inner Nuclear Membrane SUN Domain Protein Modulates Plant (a)biotic Stress Responses by Regulating Nuclear Dynamics

Molecular Plant Pathology, Volume 26, Issue 10, October 2025.
PsSUN regulates nuclear positioning and interacts with the lamin KAKU4 to maintain nuclear morphology, thereby influencin stress gene expression and plant immunity. ABSTRACT Plant inner nuclear membrane (INM) Sad1/UNC‐84 (SUN) proteins are essential for maintaining nuclear morphology, positioning and gene expression during development and environmental
Akriti Sharma, Smritilekha Mukherjee, Ankita Verma, Aryan Aryan, Divya Chandran   +4 more
wiley   +1 more source

Development of a mutation hotspot detection kit for the phenylalanine hydroxylase gene by ARMS-PCR combined with fluorescent probe technology. [PDF]

Biosci Rep, 2021
Qiang R, Wang L, He J, Xu WJ, Li W, Cai N, Wang XB, Zhang R, Zhang LP, Ma XP, Wei C, Song C, Yu W, Wang X, Li X.   +14 more
europepmc   +1 more source

In vitro activation of rat liver phenylalanine hydroxylase by phosphorylation.

, 1976
Jean‐Pierre Abita, Sheldon Milstien, N Chang, Seymour Kaufman   +3 more
openalex   +1 more source

Domain Movements upon Activation of Phenylalanine Hydroxylase Characterized by Crystallography and Chromatography-Coupled Small-Angle X-ray Scattering.

Journal of the American Chemical Society, 2016
S. Meisburger, Alexander B. Taylor, Crystal A. Khan, Shengnan Zhang, P. Fitzpatrick, N. Ando   +5 more
semanticscholar   +1 more source

Dark side of anthocyanin pigmentation

Plant Biology, Volume 27, Issue 6, Page 935-947, October 2025.
This review examines dark anthocyanin pigmentation in plants by outlining its distribution, exploring the genetic mechanisms behind its development, and discussing its ecological role together with its potential for various industrial applications. Abstract Dark pigmentation can be observed in various parts of the plant, ranging from foliage to petals ...
K. Wolff, B. Pucker
wiley   +1 more source

Separation and properties of the 6-diastereoisomers of l-erythro-tetrahydrobiopterin and their reactivities with phenylalanine hydroxylase.

, 1978
Steven Bailey, June E. Ayling
openalex   +1 more source

Epigenetic activation of phenylalanine hydroxylase in mouse erythroleukemia cells by the cytoplast of rat hepatoma cells.

, 1979
T. V. Gopalakrishnan, W.F. Anderson
openalex   +1 more source