Results 231 to 240 of about 178,348 (314)

Long-Term Treatment and Diagnosis of Tetrahydrobiopterin-Responsive Hyperphenylalaninemia with a Mutant Phenylalanine Hydroxylase Gene [PDF]

, 2003
Haruo Shintaku, Shigeo Kure, Toshihiro Ohura, Yoshiyuki Okano, Misao Ohwada, Naruji Sugiyama, Nobuo Sakura, Ichiro Yoshida, Makoto Yoshino, Yoichi Matsubara, Ken Suzuki, Kikumaro Aoki, Teruo Kitagawa   +12 more
openalex   +1 more source

An additional substrate binding site in a bacterial phenylalanine hydroxylase

European Biophysics Journal, 2013
J. Ronau, Lake N Paul, Julian E. Fuchs, Isaac R. Corn, K. T. Wagner, K. Liedl, M. Abu‐Omar, C. Das   +7 more
semanticscholar   +1 more source

Phosphorylation of Phenylalanine Hydroxylase Increases the Rate Constant for Formation of the Activated Conformation of the Enzyme. [PDF]

Biochemistry, 2018
Khan CA, Fitzpatrick PF.
europepmc   +1 more source

Modeled ligand‐protein complexes elucidate the origin of substrate specificity and provide insight into catalytic mechanisms of phenylalanine hydroxylase and tyrosine hydroxylase [PDF]

, 2003
Astrid Maaß, Joachim Scholz, Andréas Moser   +2 more
openalex   +1 more source

A new model for allosteric regulation of phenylalanine hydroxylase: implications for disease and therapeutics.

Archives of Biochemistry and Biophysics, 2013
E. Jaffe, Linda Stith, Sarah H. Lawrence, M. Andrake, Roland L. Dunbrack   +4 more
semanticscholar   +1 more source

Genotypes of patients with phenylalanine hydroxylase deficiency in the Wisconsin Amish. [PDF]

Mol Genet Metab Rep, 2018
Schwoerer JS, Drilias N, Kuhl A, Mochal S, Baker M.   +4 more
europepmc   +1 more source

Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations [PDF]

, 2004
Heidi Erlandsen, Ángel L. Pey, Alejandra Gámez, Belén Pérez, Lourdes R. Desviat, Cristina Aguado, Richard Koch, Sankar Surendran, Stephen K. Tyring, Reuben Matalon, Charles R. Scriver, Magdalena Ugarte, Aurora Martı́nez, Raymond C. Stevens   +13 more
openalex   +1 more source

Mutational and phenotypic spectrum of phenylalanine hydroxylase deficiency in Zhejiang Province, China. [PDF]

Sci Rep, 2018
Chen T, Xu W, Wu D, Han J, Zhu L, Tong F, Yang R, Zhao Z, Jiang P, Shu Q.   +9 more
europepmc   +1 more source

Probing the Role of Crystallographically Defined/Predicted Hinge-bending Regions in the Substrate-induced Global Conformational Transition and Catalytic Activation of Human Phenylalanine Hydroxylase by Single-site Mutagenesis [PDF]

, 2004
Anne Jorunn Stokka, R. Carvalho, João Filipe Barroso, Torgeir Flatmark   +3 more
openalex   +1 more source

Nutritional management of phenylalanine hydroxylase (PAH) deficiency in pediatric patients in Canada: a survey of dietitians' current practices. [PDF]

Orphanet J Rare Dis, 2019
Yuskiv N, Potter BK, Stockler S, Ueda K, Giezen A, Cheng B, Langley E, Ratko S, Austin V, Chapman M, Chakraborty P, Collet JP, Pender A, Canadian Inherited Metabolic Diseases Research Network (CIMDRN).   +13 more
europepmc   +1 more source