Results 21 to 30 of about 39,051 (241)

Dynamic regulation of phenylalanine hydroxylase

Pteridines, 2014
Phenylalanine hydroxylase (PAH) is the key enzyme in phenylalanine metabolism, catalyzing its oxidative breakdown to tyrosine. Its function in the committed step of amino acid metabolism requires strict regulation. Thus, several regulatory mechanisms are
Fuchs Julian E., Fuchs Dietmar, Liedl Klaus R.   +2 more
doaj   +1 more source

Phenylalanine Hydroxylase Deficiency and Citrin Deficiency in a Chinese Infant [PDF]

Chinese Medical Journal, 2015
Jun Ye, Wen-Juan Qiu, Lian-Shu Han, Hui-Wen Zhang, Xue-Fan Gu   +4 more
doaj   +2 more sources

Generation and analysis of an Eucalyptus globulus cDNA library constructed from seedlings subjected to low temperature conditions [PDF]

, 2008
Indexación: ScieloEucalyptus globulus is the most important commercial temperate hardwood in the world because of its wood properties and due to its characteristics for biofuel production. However, only a very low number of expressed sequence tags (ESTs)
Gamboa, Maria Cecilia, Krauskopf, Erwin, Rasmussen-Poblete, Susana, Valdes, Jorge, Valenzuela, Pablo D.T.   +4 more
core   +2 more sources

Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trials [PDF]

, 2018
Background: This study assessed the immunogenicity of pegvaliase (recombinant Anabaena variabilis phenylalanine [Phe] ammonia lyase [PAL] conjugated with polyethylene glycol [PEG]) treatment in adults with phenylketonuria (PKU) and its impact on safety ...
Atkinson, John P, Boyer, Ryan, Gu, Zhonghu, Gupta, Soumi, Harding, Cary O, Knight, Vijaya, Larimore, Kevin, Lau, Kelly, Li, Mingjin, Olbertz, Joy, Rosen, Orli, Shepherd, Gillian, Shweighardt, Becky, Weng, Haoling H, Zoog, Stephen J   +14 more
core   +2 more sources

Dynamic regulation of phenylalanine hydroxylase by simulated redox manipulation.

PLoS ONE, 2012
Recent clinical studies revealed increased phenylalanine levels and phenylalanine to tyrosine ratios in patients suffering from infection, inflammation and general immune activity.
Julian E Fuchs, Roland G Huber, Susanne von Grafenstein, Hannes G Wallnoefer, Gudrun M Spitzer, Dietmar Fuchs, Klaus R Liedl   +6 more
doaj   +1 more source

The International Working Group on Neurotransmitter related Disorders (iNTD): A worldwide research project focused on primary and secondary neurotransmitter disorders [PDF]

, 2016
INTRODUCTION: Neurotransmitters are chemical messengers that enable communication between the neurons in the synaptic cleft. Inborn errors of neurotransmitter biosynthesis, breakdown and transport are a group of very rare neurometabolic diseases ...
Cortès-Saladelafont, Elisenda, Fernández-Ramos, Joaquín A, Friedman, Jennifer, Garcia-Cazorla, Àngels, Honzik, Tomas, Horvath, Gabriella, International Working Group on Neurotransmitter related disorders (iNTD), Jeltsch, Kathrin, Jung-Klawitter, Sabine, Kurian, Manju A, Kuseyri, Oya, Lopez-Laso, Eduardo, Mastrangelo, Mario, Opladen, Thomas, Pearson, Toni, Pons, Roser, Scholl-Bürgi, Sabine, Wassenberg, Tessa   +17 more
core   +1 more source

Molecular analysis of the early interaction between the grapevine flower and Botrytis cinerea reveals that prompt activation of specific host pathways leads to fungus quiescence [PDF]

, 2017
Grape quality and yield can be impaired by bunch rot, caused by the necrotrophic fungus Botrytis cinerea. Infection often occurs at flowering, and the pathogen stays quiescent until fruit maturity.
Agudelo-Romero, Alkan, Amselem, Asselbergh, Bhuiyan, Birkenbihl, Blanco-Ulate, Boller, Bradley, Brutus, Caffall, Cantu, Choquer, Coertze, Conesa, Costa, Dadakova, Dalmais, De Cremer, Deytieux-Belleau, Du, Eichorn, Elmer, Espino, Favaron, Giannakis, Gilbert, Godfrey, Goetz, Grimplet, Guetsky, Hammerbacher, Hellemans, Höll, Jaillon, Jarvis, Jarvis, Jeandet, Jersch, Kan, Kan, Kan, Keller, Kelloniemi, Kemmerling, Kretschmer, Langcake, Law, Lebel, Lee, Leroch, Leroch, Liao, Liao, Lijavetzky, Liu, Malacarne, Marrs, Martin, McClellan, McNicol, Merz, Mlikota-Gabler, Mohnen, Monteiro, Moretto, Mullins, Nagpala, Nair, Naoumkina, Noda, Padgett, Pezet, Pezet, Prusky, Prusky, Prusky, Puhl, Rieu, Rolke, Rossi, Ruijter, Schouten, Schouten, Schumacher, Schumacher, Shaw, Smith, Smyth, Thimm, Vandesompele, Vannozzi, Velasco, Volodarsky, Vrhovsek, Waite, Weng, Wiermer, Williamson, Williamson, Zhang, Zhang, Zhao   +102 more
core   +1 more source

Incidence of Phenylketonuria in Southern Iran [PDF]

Iranian Journal of Medical Sciences, 2010
Background: Phenylketonuria is a hereditary, autosomal recessivedisorder caused by deficiency of phenylalanine hydroxylaseor its cofactor tetrahydrobiopterin.
Asadollah Habib, Mohammad Hossein Fallahzadeh, Hamid Reza Kazeroni, Amir Hossein Ganjkarimi   +3 more
doaj  

Use of sapropterin in Mexican patients with yperphenylalaninemia

Acta Pediátrica de México, 2014
Hyperphenylalaninemia is caused by deficient enzyme activity of phenylalanine hydroxylase. It was one of the first genetic disorders susceptible to treatment with a natural protein restricted diet for life.
Susana Monroy-Santoyo, Leticia Belmont-Martínez, Cynthia Fernández-Lainez   +2 more
doaj   +1 more source

Phenylalanine 4-Hydroxylase Contributes to Endophytic Bacterium Pseudomonas fluorescens’ Melatonin Biosynthesis

Frontiers in Genetics, 2021
Melatonin acts both as an antioxidant and as a growth regulatory substance in plants. Pseudomonas fluorescens endophytic bacterium has been shown to produce melatonin and increase plant resistance to abiotic stressors through increasing endogenous ...
Jian Jiao, Jian Jiao, Yan Xia, Yingli Zhang, Xueli Wu, Chonghuai Liu, Jiancan Feng, Xianbo Zheng, Shangwei Song, Tuanhui Bai, Chunhui Song, Miaomiao Wang, Hongguang Pang   +12 more
doaj   +1 more source