Results 41 to 50 of about 109,987 (177)

Elevated levels of plasma phenylalanine in schizophrenia: a guanosine triphosphate cyclohydrolase-1 metabolic pathway abnormality? [PDF]

PLoS ONE, 2014
BACKGROUND: Phenylalanine and tyrosine are precursor amino acids required for the synthesis of dopamine, the main neurotransmitter implicated in the neurobiology of schizophrenia.
Olaoluwa Okusaga, Olesja Muravitskaja, Dietmar Fuchs, Ayesha Ashraf, Sarah Hinman, Ina Giegling, Annette M Hartmann, Bettina Konte, Marion Friedl, Jason Schiffman, Elliot Hong, Gloria Reeves, Maureen Groer, Robert Dantzer, Dan Rujescu, Teodor T Postolache   +15 more
doaj   +1 more source

SbWRKY62 Coordinates With SbERF096 to Activate Pterostilbene Biosynthesis and Targets a Xylanase Inhibitor Protein for Anthracnose Resistance in Sorghum

Plant, Cell &Environment, EarlyView.
ABSTRACT Sorghum anthracnose caused by Colletotrichum sublineola (C. sublineola) is a destructive disease leading to severe crop damages. Pterostilbene is a phytoalexin that contributes to defence responses in sorghum, but the transcriptional regulation of its biosynthesis remained poorly understood.
Yajing Li, Bofu Deng, Yiming Gan, Nan Lin, Dan Zhou, Clive Lo   +5 more
wiley   +1 more source

Multiplexed Nanosensors for Real‐Time Monitoring of VOC‐Mediated Signalling Response in Plants

Plant, Cell &Environment, EarlyView.
ABSTRACT To enhance crop performance, intercropping strategies leverage volatile organic compound (VOC)‐driven interactions with companion plants that constitutively emit VOCs. Despite the agricultural importance, the mechanisms and kinetics of VOC‐mediated sensory transduction in receiver plants eavesdropping on neighbouring non‐kin emitters remain ...
Mervin Chun‐Yi Ang, Jolly Madathiparambil Saju, Sayyid Mohaideen, Niha Dhar, Sarangapani Sreelatha, Sayuj Koyyappurath, Thomas K. Porter, Gabriel Sánchez‐Velázquez, Vaishnavi Reddy Amarr, Song Wang, Duc Thinh Khong, Suh In Loh, Michael S. Strano, Sarojam Rajani   +13 more
wiley   +1 more source

Mutation Analysis of PAH Gene in Phenylketonuria Patients from the North of Iran: Identification of Three Novel Pathogenic Variants

International Journal of Preventive Medicine
Background: There are more than 1100 different pathogenic variants in the phenylalanine hydroxylase (PAH) gene that are responsible for phenylketonuria (PKU) diseases, and the spectrum of these mutations varies in different ethnic groups.
Hossein Jalali, Daniel Zamanfar, Muhammad Amirzadegan, Farshide Ghadami, Mahan Mahdavi, Mohammad Reza Mahdavi   +5 more
doaj   +1 more source

High Protein Diet and Phenylalanine Hydroxylase Activities in Rats

Pteridines, 1989
The effects of a diet of 85% casein on the activities of the phenylalanine hydroxylases of rat liver and kidney have been compared. Whereas only the tetrahydrobiopterin-dependent activity of rat hepatic phenylalanine hydroxylase is significantly ...
Carty Michael P., Beirne Edel, Donlon John   +2 more
doaj   +1 more source

Hidden Strategies Beneath a Single Nucleotide: Contrasting Physiology in Lichen Photobiont Strains

Plant, Cell &Environment, EarlyView.
ABSTRACT Lichen photobionts exhibit significant physiological variability with important ecological implications. While this variability is relatively well studied at the interspecific level, it has rarely been examined at the intraspecific level. Here, we investigated the physiological responses to temperature and irradiance of two Trebouxia lynniae ...
Miguel Blázquez, David Pizarro, Ana García‐Muñoz, Raquel Pino‐Bodas, Asunción de los Ríos, Miren I. Arzac, José Ignacio García‐Plazaola, Beatriz Fernández‐Marín, Unai Artetxe, Rosa Toledo‐Gil, Fernando Vallejo, Leonardo M. Casano, Israel Pérez‐Vargas, Sergio Pérez‐Ortega, Francisco Gasulla   +14 more
wiley   +1 more source

Hydroxycinnamic Acid Amides Emerge as Multifunctional Molecules Involved in Regeneration and Volatile Signalling During Wound Responses

Plant, Cell &Environment, EarlyView.
ABSTRACT Hydroxycinnamic acid amides (HCAAs) are phenylpropanoid‐derived metabolites traditionally associated with antimicrobial defence and cell wall reinforcement during plant–pathogen interactions. However, their contribution to plant responses to mechanical injury, particularly in wound healing and damage‐induced signalling, remains poorly ...
Carmen Grech‐Hernández, Andrade Cynthia, Francisco Vera‐Sirera, Álvaro Luis Jiménez‐Jiménez, Marc Valls, Nuria S. Coll, Ismael Rodrigo, José María Bellés, María Pilar López‐Gresa, Purificación Lisón   +9 more
wiley   +1 more source

Blue boost: Monochromatic blue light and blue‐enriched spectra (RBW) enhance physiology, bioactive compounds, and yield of strawberry in indoor vertical farming

Photochemistry and Photobiology, EarlyView.
Effects of spectral quality and light regime on the physiological, biochemical, and agronomic responses of strawberry plants grown in an indoor aeroponic system. Constant blue and red light and sinusoidal red and red–blue–white (RBW) light regimes differentially modulated photosynthetic performance, stomatal regulation, antioxidant metabolism, carbon ...
Carlos Henrique Pereira Bento, Fabia Barbosa da Silva, Márcio Rosa, Tiago do Prado Paim, Ítalo Moraes Rocha Guedes, Luciana Arantes Dantas, Erika Crispim Resende, Aurélio Rúbio Neto, Lucas de Jesus Silva, Nyah Dias Mazieri, Fabiano Guimarães Silva   +10 more
wiley   +1 more source

Structural basis of autoregulation of phenylalanine hydroxylase

, 1999
Phenylalanine hydroxylase converts phenylalanine to tyrosine, a rate-limiting step in phenylalanine catabolism and protein and neurotransmitter biosynthesis.
Goodwill, KE, Jennings, IG, Michell, BJ, Santarsiero, BD, House, CM, Stevens, RC, Cotton, RGH, Kobe, B, Kemp, BE   +8 more
core   +1 more source

The effect of streptozotocin-induced diabetes on phenylalanine hydroxylase expression in rat liver

, 1989
The impact of experimentally induced diabetes on the expression of rat liver phenylalanine hydroxylase has been investigated. A significant elevation in maximal enzymic activity was observed in diabetes.
AK Green (14574539), HHM Dahl (14574527), Julian Mercer (13076475), MJ Fisher (14574542), DS Taylor (14574536)   +4 more
core   +1 more source