Results 231 to 240 of about 18,026 (280)
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Pattern of Phenylbutazone Degradation
Journal of Pharmaceutical Sciences, 1973Phenylbutazone and phenylbutazone-antacid formulations were examined by TLC for the presence of decomposition products. A procedure was developed for minimizing on-plate oxidation of phenylbutazone during TLC analysis, and preparative TLC was utilized for isolation of the major products of decomposition. Unequivocal identification of the major products
F. Matsui, A. Vincent, D.V.C. Awang
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The Antithyroid Effect of Phenylbutazone
Acta Rheumatologica Scandinavica, 1956SummaryOn 19 patients undergoing Phenylbutazone treatment, 600 mg. by mouth per day for various rheumatic complaints, the antithyroid effect of this drug was studied by the use of repeated tracer iodine tests. The uptake values were reduced after one week's treatment but this effect tended to revert after further treatment.
A.-M. Allgoth +2 more
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Management of thrombophlebitis with phenylbutazone
The American Journal of Cardiology, 1959I T IS my purpose to present a treatment for thrombophlebitis which aborts the clinical syndrome, cuts down on the need for nursing care and hospitalization, and has a potential for lessening the long term complications of venous thrombosis. These objectives are attained through the use of phenylhutazone,t a nonhormonal drug with anti-inflammatory ...
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AGRANULOCYTOSIS DUE TO PHENYLBUTAZONE
Annals of Internal Medicine, 1957Excerpt It is well known that phenylbutazone is a hazardous medication, although it has been very effective therapeutically in relief of pain of arthritis and similar conditions.
R E Geesaman, F L James
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Misuse of Veterinary Phenylbutazone
Archives of Internal Medicine, 1995Phenylbutazone is a nonsteroidal anti-inflammatory drug that was commonly prescribed for the treatment of arthritic conditions; it is no longer available for use in humans because of its numerous side effects, including aplastic anemia. We describe a horse trainer who developed gastric ulcers and renal insufficiency as a result of taking veterinary ...
W M McDonnell, S L Carpenter
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PHENYLBUTAZONE AND AGRANULOCYTOSIS
JAMA: The Journal of the American Medical Association, 1953To the Editor: —I have just read with interest the report "Agranulocytosis Following Use of Phenylbutazone (Butazolidin ® )" by Hinz and others inThe Journal, Jan. 3, 1953, page 38. During the past year and a half, I have obtained a great deal of experience from using this drug in the treatment of over 700 patients with various arthritides and ...
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Effects of Phenylbutazone in Gout
New England Journal of Medicine, 1954PHENYLBUTAZONE (3, 5-dioxo-l, 2–diphenyl4-n-butyl-pyrazolidin sodium) is a pyrazolon derivative with anti-inflammatory and analgesic properties.1 Its formula is as follows: Success with this drug in the treatment of gout has previously been reported by Gutman and Yu,2 by Kuzell et al.,3 , 4 and by Steinbrocker and his associates.5 In the past year we ...
Peter H. Forsham +5 more
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Phenylbutazone and Indomethacin
Clinics in Rheumatic Diseases, 1975SUMMARY This chapter reviews the demonstration of the analgesic and anti-inflammatory effects of phenylbutazone and indomethacin, and attempts to explain their mode of action in terms of effects on mediators of inflammation, tissue and cellular metabolism and reaction with protein molecules.
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Journal of Veterinary Pharmacology and Therapeutics, 2018
S. Pedersen +4 more
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S. Pedersen +4 more
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