Results 31 to 40 of about 974 (165)

Enantioseparation of Mirabegron Using Cyclodextrin‐based Chiral Columns: High‐performance Liquid Chromatography and Molecular Modeling Study

Journal of Separation Science, Volume 48, Issue 4, April 2025.
ABSTRACT A novel high‐performance liquid chromatography method for the enantioseparation of mirabegron (R‐mirabegron), a selective β‐3 adrenergic receptor agonist, using cyclodextrin (CD)‐based chiral stationary phases (CSPs) was developed. Seven different CSPs containing β‐, γ‐, hydroxypropyl‐β‐, sulfobutyl‐β‐, carboxymethyl‐β‐, permethyl‐β‐, and ...
Ali Mhammad, Gergely Dombi, Máté Dobó, Zoltán‐István Szabó, Béla Fiser, Gergő Tóth   +5 more
wiley   +1 more source

Understanding Efflux‐Mediated Multidrug Resistance in Botrytis cinerea for Improved Management of Fungicide Resistance

Microbial Biotechnology, Volume 18, Issue 3, March 2025.
ABC efflux transporters, which can expel various toxic substances, play an important role in the efflux‐mediated resistance of Botrytis cinerea to multiple fungicides. Effective regulation of the pumps, such as synergistic effects via efflux inhibition, will provide a viable strategy to control the challenge of fungal MDR.
Zhaochen Wu, Junting Zhang, Jianjun Hao, Pengfei Liu, Xili Liu   +4 more
wiley   +1 more source

Modes of Action of Different Classes of Herbicides [PDF]

, 2015
The mode of action of herbicides is important for understanding the management, classification, organization, and hierarchy of the herbicides. It also provides an insight into herbicide resistance, which continues to be a problem in sustainable ...
Arif, Ibrahim A., Khan, Haseeb A., Sherwani, Shariq I.   +2 more
core   +1 more source

Improving CYP2C19 phenotyping using stereoselective omeprazole and 5‐hydroxy‐omeprazole metabolic ratios

Basic &Clinical Pharmacology &Toxicology, Volume 135, Issue 6, Page 755-766, December 2024.
Abstract Omeprazole (OME) is a CYP2C19 phenotyping probe, marketed as a racemic (S)/(R) mixture or as an S‐enantiomer. Both CYP2C19 and CYP3A4 enzymes mediate (R)‐OME hydroxylation to (R)‐5‐hydroxyomeprazole, while (S)‐OME is exclusively hydroxylated via CYP2C19.
Kenza Abouir, Emmanuel Varesio, Julien Déglon, Caroline Samer, Youssef Daali   +4 more
wiley   +1 more source

Quantifying the cooperative evolution of microphase segregation and nanostructural order in annealed polyurethanes of MDI‐BDO‐PTHF

Journal of Polymer Science, Volume 62, Issue 13, Page 2988-3012, 1 July 2024.
Abstract Here, we quantify the relationship between microphase segregation and local structure development in thermoplastic polyurethanes. Samples were prepared with varying ratios of 4,4′‐methylene diphenyl diisocyanate (MDI) and 1,4‐butanediol (BDO) to polytetrahydrofuran (PTHF) and annealed at temperatures Ta between RT–140 °C for 20 h each ...
Maxwell W. Terban, Elmar Pöselt, Marc Malfois, Armin Schulz, Edgar Schander, A. M. Milinda Abeykoon, Bernd Hinrichsen, Robert E. Dinnebier   +7 more
wiley   +1 more source

Molecular structure and selective theophylline complexation by conformational change of diethyl N,N′‐(1,3‐phenylene)dicarbamate

Acta Crystallographica Section C, Volume 80, Issue 6, Page 190-199, June 2024.
The diethyl N,N′‐(1,3‐phenylene)dicarbamate–theophylline (1–TEO) complex was obtained by mechanochemistry involving the conformational change of one of the ethyl carbamate groups of 1 from the endo conformation to the exo conformation to allow the formation of intermolecular interactions.The receptor ability of diethyl N,N′‐(1,3‐phenylene)dicarbamate ...
Juan Saulo González-González, Alfonso Martínez-Santos, María José Emparán-Legaspi, Armando Pineda-Contreras, Francisco Javier Martínez-Martínez, Marcos Flores-Alamo, Hector García-Ortega   +6 more
wiley   +1 more source

Synthesis of Some Carhamates of Steroidal Lactams and Lactones as Possible Alkylating Agents [PDF]

, 1976
16-0xo-l 7 a-aza-5o.-androstan-3-yl N-alkyl/phenylcarbamates (I-V), 16-oxo-l 7a-oxa-5a-androstan-3-yl N-ethylcarbamate (VI), 16-oxo-l 7a-aza-5-androsten-3-yl N-alkyl/phenylcarbamates (VII-:IX) and 4-oxo-3-aza-A-homo-4a-androsten-l 7B-yl N ...
E. Souli, P. Catsoulacos
core   +1 more source

Ecotoxicity Thresholds for Ametryn, Diuron, Hexazinone and Simazine in Fresh and Marine Waters [PDF]

, 2018
Triazine and urea herbicides are two groups of photosystem II inhibiting herbicides frequently detected in surface, ground and marine waters. Yet, there are few water quality guidelines for herbicides. Ecotoxicity thresholds (ETs) for ametryn, hexazinone
A Claver, A Hildebrandt, A Wightwick, D O’Brien, DA Hobbs, EC (European Commission), HJ Klimisch, IK Konstantinou, IK Konstantinou, JL Durda, JW Green, K Schneider, KR Solomon, KV Thomas, L Guzzella, M Gfrerer, M Muschal, M Ågerstrand, Michael St. J. Warne, MSJ Warne, MSJ Warne, Olivia King, P Mercurio, R Smith, RA Dam van, RA Smith, Rachael A. Smith, SM Peterson   +27 more
core   +1 more source

Thermodynamic and Catalytic Insights into Non‐Reductive Transformation of CO2 with Amines into Organic Urea Derivatives

ChemCatChem, Volume 16, Issue 6, March 22, 2024.
Thermodynamics and catalysis: Non‐reductive conversion of CO2 with amines to produce value‐added organic urea derivatives has been overviewed from the viewpoints of both thermodynamics and catalysis. The lessons described in this review could be helpful for the assessment of developed catalytic systems and further improvement of efficiency of CO2 ...
Mizuho Yabushita, Ryotaro Fujii, Yoshinao Nakagawa, Keiichi Tomishige   +3 more
wiley   +1 more source

ACUTE RODENTICIDES IN THE CONTROL OF RODENT PEST IN CHINA: A REVIEW [PDF]

, 1984
In China, the earliest record, The Book of Song, vividly describes that farmers complained of rodent damage and earnestly hoped rodents did not eat their crops.
Wang, Zuwang
core   +1 more source