Results 61 to 70 of about 30,878 (268)

Serum prolactin as a biomarker for the study of intracerebral dopamine effect in adult patients with phenylketonuria: a cross-sectional monocentric study [PDF]

, 2016
BACKGROUND: It has been previously postulated that high phenylalanine (Phe) might disturb intracerebral dopamine production, which is the main regulator of prolactin secretion in the pituitary gland.
AB Burlina, C Landvogt, CM McKean, D Vliet van, D Vliet van, F Güttler, FJ Spronsen van, HC Curtius, HE Carlson, HE Carlson, J Denecke, J Weglage, KD Wang, KH Schulpis, M Spada, M Velema, MJ Groot de, N Ben-Jonathan, N Blau, W Krause   +19 more
core   +2 more sources

Neonatal Phenylketonuria Screening Indices in Kerman district during 2013-2017

پژوهش‌های سلامت‌محور, 2019
Neonatal Phenylketonuria Screening Indices in Kerman District during 2013-2017   Bavafa Babak1, Ahmadipour Habibeh2*, Bigham Eshrat3   1. Pediatrician, Focal Point of Phenylketonuria, Family Physician Clinic, Afzalipour School of Medicine, Kerman ...
Babak Bavafa, Habibeh Ahmadipour, Eshrat Bigham   +2 more
doaj  

Measurement of Neopterin and Biopterin in Urine from Phenylketonuria Heterozygotes and Normal Controls

Pteridines, 1991
The effect of an oral load of phenylalanine (100 mg/kg body weight) on the levels of neopterin and biopterin in urine has been determined in 8 heterozygotes for classical phenylketonuria and 25 supposed normal controls. In basal conditions, neopterin and
Ruiz-Vázquez P., Bel Y., Garcia A. M., Cabello M. L., Dalmau J., Alós T., Catalá J. L., Ferré J.   +7 more
doaj   +1 more source

Federation of Gynecology and Obstetrics good practice recommendations on preconception care: A strategy to prevent preterm birth

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Preterm birth (PTB) remains one of the leading causes of neonatal mortality and long‐term morbidity worldwide, with minimal progress being made in reducing its incidence, particularly in low‐resource settings. Preconception care is recognized as an effective strategy for PTB prevention; however, the fact that more than half of pregnancies ...
Leticia Irma Ojeda, Catalina M. Valencia G, Natalia Cardozo Buitrago, Dilly Anumba, Wondimu Gudu, Ana Bianchi, Bo Jacobson, on behalf of the FIGO Committee for Preterm Birth, Catalina M. Valencia González, Dilly Anumba, Wondimu Gudu, Bo Jacobsson, Nancy Sierra Lozada, Leticia Ojeda, Madhuri Patel, Andrew Shennan, Rodrigo Rigoni, Priya Soma‐Pillay, Sherri Ann Suplido, Ana Daneva, Sikolia Wanyonyi, Haim Abenhaim   +21 more
wiley   +1 more source

Reproductive experience of women living with phenylketonuria

Molecular Genetics and Metabolism Reports, 2018
Introduction: Many women with PKU are well-informed about the risks of maternal PKU but there are several barriers to achieving satisfactory metabolic control before and during pregnancy.
Suzanne Ford, Mike O'Driscoll, Anita MacDonald   +2 more
doaj   +1 more source

New insights into applications of base editor in hereditary disorders

Interdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai, Linhui Zhang, Liqing Li, Yue Liu, Canbin Lv, Yan Shi, Jianyuan Zhao, Dingwei Ye, Yuanyuan Qu   +8 more
wiley   +1 more source

Hydrophobic Drug Delivery into T Cells Using Carboxy‐Terminal Phenylalanine‐Modified Dendrigraft Polylysines

Macromolecular Bioscience, EarlyView.
In this study, dendrigraft polylysines (DGLs) modified with 1,2‐cyclohexanedicarboxylic acid (CHex) and phenylalanine (Phe) were synthesized using different generations of DGL by reacting with Phe at different ratios for drug delivery to T cells. DGL(G3)‐CHex‐Phe93 was associated with T cells efficiently, retained a model hydrophobic drug, paclitaxel ...
Chie Kojima, Akinobu Sakai, Tetsuya Kadonosono   +2 more
wiley   +1 more source

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

MODERN PRINCIPLES OF DIET ORGANIZATION IN CHILDREN IN DIFFERENT AGE WITH PHENYLKETONURIA

Вопросы современной педиатрии, 2010
The article reports questions of diet organization in children with phenylketonuria in different age with the use of modern specialized food. Authors give examples of calculation of diet based on new norms of needs in energy and food for different groups
T.V. Bushuyeva, T.E. Borovik
doaj   +2 more sources

Open Framework Structure of the New Pure‐Germania Zeolite ITQ‐35 Solved by 3D Electron Diffraction

Small Methods, EarlyView.
The synthesis and characterization of the pure germania zeolite ITQ‐35 are described. Its complete structure determination, including the organic structure directing agent, is performed using 3D electron diffraction, theoretical calculations, and powder X‐ray diffraction data.
Juan Ignacio Tirado, Jose Valero, Partha Pratim Das, Lukáš Palatinus, Stavros Nicolopoulos, Jose Luis Jordá, German Sastre, Angel Cantín, Susana Valencia, Fernando Rey   +9 more
wiley   +1 more source