Reproxalap ‐ A Novel Treatment Option for Allergic Conjunctivitis – A Comprehensive Narrative Review
Health Science Reports, Volume 9, Issue 6, June 2026.ABSTRACT Background and Aims Allergic conjunctivitis is a prevalent, immune‐mediated hypersensitivity disorder of the ocular surface affecting 10%–20% of the global population. Current therapeutic options, while effective to some extent, are often limited by side effects and inconsistent efficacy.
Sanila Mughal +7 more
wiley +1 more source
Increased Brown Adipose Tissue Thermogenesis in Phenylketonuria
MedComm, Volume 7, Issue 6, June 2026.In phenylketonuria (PKU), elevated phenylalanine (Phe) increases hepatic fibroblast growth factor 21 (FGF21) and thyroid hormones, enhancing brown adipose tissue (BAT) thermogenesis in patients. Central FGF21 reproduces this phenotype in rodents via reduced hypothalamic AMP‐activated protein kinase (AMPK) activity in the ventromedial nucleus of the ...
Noemí López‐Rey +18 more
wiley +1 more source
What Advanced Practice Roles Are Dietitians Undertaking? A Mixed Methods Systematic Review
Journal of Human Nutrition and Dietetics, Volume 39, Issue 3, June 2026.ABSTRACT Background As health systems globally are facing unprecedented demands, allied health clinicians undertaking advanced practice (AP) roles are increasingly supporting medical professionals, improving health system efficiencies and outcomes. The aim of this mixed methods systematic review was to identify what AP roles dietitians are undertaking ...
Kim Lunardi +2 more
wiley +1 more source
The Indicator Amino Acid Oxidation Method with the Use of L-[1-13C]Leucine Suggests a Higher than Currently Recommended Protein Requirement in Children with Phenylketonuria [PDF]
, 2017 Abrar Turki +6 more
openalex +1 more source
Re: Pegvaliase Treatment for Adolescents With Phenylketonuria: A Multi‐Site Study
JIMD Reports, Volume 67, Issue 4, July 2026.
Patricia L. Hall +2 more
wiley +1 more source
Estimating Correlations Between Clinical Trial Outcomes Using Generalised Estimating Equations
Oxford Bulletin of Economics and Statistics, Volume 88, Issue 3, Page 553-567, June 2026.ABSTRACT Accurately estimating the correlations among clinical trial outcomes is crucial for managing the risk of biopharmaceutical investment portfolios. We propose a novel algorithm for estimating correlations in large clinical trial datasets using a generalised estimating equations (GEE) framework.
Yuehao Dai +4 more
wiley +1 more source
Functional and structural connectivity of thalamic subnuclei in major depressive disorder at 7 Tesla
Psychiatry and Clinical Neurosciences, Volume 80, Issue 6, Page 477-489, June 2026.Aims Major depressive disorder (MDD) is widely considered to be a mood disorder characterized by altered connectivity. The thalamus plays an important role in MDD by connecting large areas of the brain. Here, we explored thalamic connectivity in MDD at the subnuclear level using ultra‐high‐field MRI.
Weijian Liu +10 more
wiley +1 more source
Journal of Geophysical Research: Atmospheres, Volume 131, Issue 10, 28 May 2026.Abstract Ammonia (NH3) is a short‐lived atmospheric pollutant with significant environmental and health impacts. Monitoring NH3 remains challenging, as diurnal variability at local scales is still poorly documented. In this study, we analyze two years (July 2022–June 2024) of NH3 total columns from the Geostationary Interferometric Infrared Sounder ...
Nadir Guendouz +13 more
wiley +1 more source
New challenges in management of phenylketonuria in pregnancy: a case report. [PDF]
J Med Case Rep, 2023 Ugalde-Abiega B +4 more
europepmc +1 more source