Results 41 to 50 of about 1,229 (164)

N‐Arachidonoyl‐phosphatidylethanolamide phospholipase D activation by muscarinic receptors

The Journal of Physiology, EarlyView.
Abstract figure legend Activating muscarinic M3 receptors activates Gq‐pathway signalling, including the activation of phospholipase C (PLC) and release of calcium from internal stores as shown in the upper panel. It remains unclear whether the calcium acts on N‐arachidonoyl‐phosphatidylethanolamide phospholipase D (NAPE‐PLD) itself or upstream at N ...
Natalia Murataeva, Connor Schmitt, Elyssa Hyman, Jim Wager‐Miller, Irene Matthews, Ruyi Cai, Shangxuan Cai, Yulong Li, Ken Mackie, Alex Straiker   +9 more
wiley   +1 more source

Phenylketonuria: a review [PDF]

Postgraduate Medical Journal, 1970
SummaryThe development of a practical screening procedure for phenylketonuria and the improvement in methods of chemical analysis have led to a realization that Folling’s (1934) disease of phenylketonuria is not a single entity.In this commentary, the current view on some aspects of phenylketonuria will be reviewed and the problems illustrated by ...
openaire   +2 more sources

Spectrum of Phenylalanine Hydroxylase Gene Mutations in Hamadan and Lorestan Provinces of Iran and Their Associations with Variable Number of Tandem Repeat Alleles

Iranian Journal of Medical Sciences, 2018
Phenylketonuria (PKU) is one of the most common known inherited metabolic diseases. The present study aimed to investigate the status of molecular defects in phenylalanine hydroxylase (PAH) gene in western Iranian PKU patients (predominantly from ...
Reza Alibakhshi, Keivan Moradi, Mostafa Biglari, Samaneh Shafieenia   +3 more
doaj  

A tsRNA Suppresses Lung Adenocarcinoma Progression Through Targeting Glucose‐6‐Phosphate Dehydrogenase

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Structure of tsRNA‐Thr‐5‐0096. Mechanically, tsRNA‐Thr‐5‐0096 suppresses LUAD progression by targeting G6PD which regulates glycolysis and oxidative stress. ABSTRACT Elucidating the molecular distinctions between invasive and non‐invasive forms of lung adenocarcinoma is essential for the development of personalized therapeutic approaches and the ...
Suo Sha, Meilin Zhang, Qinsong Tao, Yang Liu, Junjun Bao, Ping Guo, Aiting Yan, Cuizhu Wang   +7 more
wiley   +1 more source

A Framework to Establish Diet and Nutrition Competencies for Oral Health Care Education

Journal of Dental Education, Volume 90, Issue 9, Page 1350-1362, September 2026.
ABSTRACT Objective To prevent and manage oral disease, oral health care practitioners (OHCPs) must provide dietary counseling based on nutrition science. OHCPs are often ill‐equipped to provide such counseling due to fragmented and inadequate dietary education, which is typically attributed to limited curricular time or appropriately qualified faculty.
Teresa A. Marshall, Michael Crowe, Riva Touger‐Decker   +2 more
wiley   +1 more source

Phenylketonuria [PDF]

BMJ, 1963
J D, ALLAN, K S, HOLT, F P, HUDSON, J T, IRELAND   +3 more
openaire   +2 more sources

Characterization of Adult Patients With Neurometabolic Disorders: A Cross‐Sectional Study at a Tertiary Neurology Center in Sweden

JIMD Reports, Volume 67, Issue 5, September 2026.
ABSTRACT Adult patients with inherited metabolic diseases are often overlooked. Limited data on this population hinder adequate planning of their clinical and social care. In this retrospective, observational, cross‐sectional service evaluation study, we reviewed the electronic medical records of adult patients with inherited neurometabolic diseases ...
Boel Ernerdahl, Ashraf Yahia, Andreas Puschmann   +2 more
wiley   +1 more source

Amino Acid Metabolism in Health and Disease

MedComm, Volume 7, Issue 9, September 2026.
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su, Jinyu Liu, Xiaoliang Deng, Yanqun Luo, Haiping Xue, Lei Wang, Lianjun Xing, Tao Wu   +7 more
wiley   +1 more source

High‐Content CRISPR Screening: Methods and Applications

MedComm, Volume 7, Issue 9, September 2026.
High‐content CRISPR screening represents a paradigm shift in functional genomics, moving beyond traditional survival‐based readouts to enable multidimensional mapping of genotype–phenotype relationships. This review systematically outlines the methodological evolution of this approach, detailing advances in perturbation modalities, delivery systems ...
Yike Zhang, Yimeng Zhang, Xudong Tang, Xinyu Deng, Yitian Zhou, Yanfeng Wu, Jianhua Luo   +6 more
wiley   +1 more source

FinTech and Bank Efficiency in China: Evidence From a Dynamic Network Perspective

International Review of Finance, Volume 26, Issue 3, September 2026.
ABSTRACT This paper examines whether and through which channels financial technology (FinTech) development improves the efficiency of commercial banks. We adopt a meso‐level perspective by measuring external FinTech exposure with two complementary indicators: industry‐level innovation intensity (FinTech‐related Bank Technology Development Awards) and ...
Lifang Li, Mengqi Ouyang, Fangming Xu
wiley   +1 more source