Results 11 to 20 of about 503 (122)

Novel Sulfonium Reagents for the Modular Synthesis of Spiro[2.3]Hexanes and Heteroatom-Containing Analogues: Synthesis, Application, and Evaluation as Bioisosteres. [PDF]

Angew Chem Int Ed Engl
Strained spirocyclic spiro[2.3]hexane and its heteroatom‐containing derivatives, including previously underrepresented 5‐oxa‐1‐azaspiro[2.3]hexanes and 1,5‐diazaspiro[2.3]hexanes, were synthesized via a modular approach of insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into alkenes, carbonyls and imines.
Natho P, Vicenti A, Mastrolorito F, De Franco F, Walsh-Benn L, Colella M, Mesto E, Schingaro E, Nicolotti O, Gioiello A, Luisi R.   +10 more
europepmc   +3 more sources

Boosting the Nucleophilicity of the Diphenylphosphide Anion with Crown Ether Supported Heavy Alkali Metals to Facilitate Highly Efficient Catalytic Alkene Isomerisation. [PDF]

Angew Chem Int Ed Engl
Here, we report a breakthrough study in catalytic alkene isomerisation using crown ether‐supported alkali metal phosphides in which the activity increases sequentially and significantly as Group One is descended with Cs(18‐crown‐6)PPh2 (1Cs) performing best.
Krämer F, Downie TMH, Mulvey RE.
europepmc   +3 more sources

Plasmonic Catalysis for Controlling Selectivity in the Hydrogenation of Cinnamaldehyde to Propylbenzene Under Visible-Light Irradiation. [PDF]

ChemSusChem
A plasmonic Au@Au3Pd catalyst that integrates visible‐light‐driven hot electron generation with bimetallic electronic tuning to steer the selective hydrogenation of cinnamaldehyde toward propylbenzene is reported. Localized surface plasmon resonance excitation modulates reaction pathways on tailored Au–Pd interfaces, enabling product selectivity under ...
Frindy S, Wang S, Sullivan-Allsop S, Cai R, Slater TJA, Haigh SJ, Camargo PHC.   +6 more
europepmc   +2 more sources

Preparation, Encapsulation, and Performance Evaluation of Ternary Phase Change Materials for Building Envelope

Advances in Civil Engineering, 2022
Background. In order to make up for the defect that a single phase change material cannot meet the phase change temperature in a specific application field, three kinds of materials with higher phase change temperature are selected in this paper. Through
Hongzhi Zhu, Bin Guo, Zhi Li
doaj   +1 more source

Antibacterial Activity of Estragole From Ocimum tenuiflorum, and Tagetes lucida and Synergistic Effect With Meropenem and Tobramycin Against Multidrug- and Extensively Drug-Resistant (MDR-XDR) Gram-Negative Bacteria. [PDF]

Microbiologyopen
This study reveals estragole's bactericidal activity against MDR/XDR Gram‐negative pathogens. Synergy with meropenem and tobramycin was observed in > 88% of strains, reducing antibiotic MICs up to 16‐fold. Estragole represents a promising therapeutic adjuvant to enhance antibiotic efficacy and combat antimicrobial resistance.
Araque M, Rojas LB.
europepmc   +2 more sources

Phyto-Computational Intervention of Diabetes Mellitus at Multiple Stages Using Isoeugenol from Ocimum tenuiflorum: A Combination of Pharmacokinetics and Molecular Modelling Approaches

Molecules, 2022
In the present study, the anti-diabetic potential of Ocimum tenuiflorum was investigated using computational techniques for α-glucosidase, α-amylase, aldose reductase, and glycation at multiple stages.
Reshma Mary Martiz, Shashank M. Patil, Deepika Thirumalapura Hombegowda, Abdullah M. Shbeer, Taha Alqadi, Mohammed Al-Ghorbani, Ramith Ramu, Ashwini Prasad   +7 more
doaj   +1 more source

Cloning and Expression of a Perilla frutescens Cytochrome P450 Enzyme Catalyzing the Hydroxylation of Phenylpropenes

Plants, 2020
Phenylpropanoid volatile components in plants are useful and valuable not only as flavorings, but also as medicines and food supplements. The pharmacological actions and toxicities of these compounds have been well studied but their synthetic pathways ...
Mariko Baba, Ken-ichi Yamada, Michiho Ito   +2 more
doaj   +1 more source

p53 triggers mitochondrial apoptosis following DNA damage-dependent replication stress by the hepatotoxin methyleugenol

Cell Death and Disease, 2022
Liver cancer is one of the most frequent tumor entities worldwide, which is causally linked to viral infection, fatty liver disease, life-style factors and food-borne carcinogens, particularly aflatoxins.
Max J. Carlsson, Anastasia S. Vollmer, Philipp Demuth, Daniel Heylmann, Diana Reich, Caroline Quarz, Birgit Rasenberger, Teodora Nikolova, Thomas G. Hofmann, Markus Christmann, Julia A. Fuhlbrueck, Simone Stegmüller, Elke Richling, Alexander T. Cartus, Jörg Fahrer   +14 more
doaj   +1 more source

Water-Catalytic Deconstructive and Proton Transfer Cyclopropanation of Sulfoxonium Ylide with Olefin. [PDF]

Adv Sci (Weinh)
Water‐catalytic deconstructive and proton transfer cyclopropanation of sulfoxonium ylide with olefin is developed through a sequential water‐mediated ring‐closing/opening reaction. This atom‐economical, environmentally friendly methodology offers easy access to a range of cyclopropyl ketones with moderate to good yields.
Yu X, Huang L, Yang H, Song L, Jin Y.
europepmc   +2 more sources

Isoeugenol has a non-Disruptive Detergent-like Mechanism of Action

Frontiers in Microbiology, 2015
Isoeugenol is an essential oil constituent of nutmeg, clove, and cinnamon. Despite isoeugenol’s promising antimicrobial activity, no studies have yet investigated its mode of antibacterial action at the molecular level.
Morten eHyldgaard, Morten eHyldgaard, Tina eMygind, Roxana ePiotrowska, Morten eFoss, Rikke Louise Meyer, Rikke Louise Meyer   +6 more
doaj   +1 more source