Results 31 to 40 of about 49,960 (234)

‘Adrenal rush’ in a patient with Neurofibromatosis-1

Journal of Community Hospital Internal Medicine Perspectives, 2020
Neurofibromatosis-1 (NF-1) is a genetic neuro-cutaneous disorder that is associated with an increased prevalence of pheochromocytoma (PHEO). However, this association may not be commonly anticipated by physicians, as patients may be normotensive.
Samiha Khan, Beenish Fayyaz, Janki Patel
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Comparison of pheochromocytoma-specific morbidity and mortality among adults with bilateral pheochromocytomas undergoing total adrenalectomy vs cortical-sparing adrenalectomy

, 2019
Importance Large studies investigating long-term outcomes of patients with bilateral pheochromocytomas treated with either total or cortical-sparing adrenalectomies are needed to inform clinical management.Objective To determine the association of ...
Eng, Charis, International Bilateral-Pheochromocytoma-Registry Group, [Study group], Neumann, Hartmut P. H.   +2 more
core   +1 more source

Adrenocorticotropic Hormone Secreting Pheochromocytoma Underlying Glucocorticoid Induced Pheochromocytoma Crisis [PDF]

, 2018
Context. Pheochromocytomas are hormone secreting tumors of the medulla of the adrenal glands found in 0.1–0.5% of patients with hypertension. The vast majority of pheochromocytomas secrete catecholamines, but they have been occasionally shown to also ...
Matan Fischer, Haggi Mazeh, Gil A. Geva, Iddo Z. Ben-Dov, David J. Gross, Karine Atlan   +5 more
core   +1 more source

Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus‐Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo‐Controlled Ion Release

Advanced Science, EarlyView.
TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang, Yuping Zhang, Xiaoning Su, Ning Liu, Hui Zeng, Bo Yang, Yang Xue, Fang Guo, Changkui Liu   +8 more
wiley   +1 more source

Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma

, 2010
Pheochromocytomas are rare neoplasias of neural crest origin arising from chromaffin cells of the adrenal medulla and sympathetic ganglia (extra-adrenal pheochromocytoma).
Neff, Frauke, Höfler, Heinz, Neff, F., Mannelli, Massimo, Perren, A., Beuschlein, F., Wloch, J., Jarzab, B., Pellegata, N.S., Martin Irmler, Jan Wloch, Zoubaa, S., Höfler, H., Tonino Ercolino, Jarzab, Barbara, Wloch, Jan, Beckers, J., Aurel Perren, Ercolino, T., Molatore, Sara, Pellegata, Natalia S, Perren, Aurel, Molatore, S., Mannelli, M., Natalia S. Pellegata, Sara Molatore, Jacek Ziaja, Zoubaa, Saida, Liyanarachchi, Sandya, Barbara Jarzab, Irmler, M., Massimo Mannelli, Michael J. Atkinson, Frauke Neff, Heinz Höfler, Saida Zoubaa, Liyanarachchi, S., Irmler, Martin, Beuschlein, Felix, Beckers, Johannes, Ziaja, J., Ercolino, Tonino, Felix Beuschlein, Johannes Beckers, Atkinson, M.J., Atkinson, Michael J, Sandya Liyanarachchi, Ziaja, Jacek   +47 more
core   +1 more source

Clinical comparison and genetic analysis in pheochromocytoma with primary aldosteronism

Endocrine Journal
Pheochromocytoma is a rare form of adrenal hypertension. This study aimed to investigate the clinical characteristics and associated genetic mutations in patients with pheochromocytoma and primary aldosteronism.
Xurong Mai, Mitsuhiro Kometani, Toshiaki Kato, Ko Aiga, Shigehiro Karashima, Daisuke Aono, Seigo Konishi, Koshiro Nishimoto, Kazuyoshi Hosomichi, Atsushi Watanabe, Yuko Noda, Yoshiyu Takeda, Takashi Yoneda   +12 more
doaj   +1 more source

Bacteria‐Derived 1‐Allylpiperazine Alleviates Symptoms of Parkinson's Disease Model by Promoting Autophagy

Advanced Science, EarlyView.
Parkinson's disease currently has no disease‐modifying therapies. In Caenorhabditis elegans, Escherichia coli E8 alleviates α‐synuclein‐provoked PD‐related defects through its bioactive metabolite 1‐ALPP, which combats PD by triggering AMPK/mTOR/HLH‐30‐dependent autophagy and suppressing α‐synuclein LLPS‐mediated fibrillization.
Mingqin Qu, Xinyuan Zhang, Xinyi Chen, Jiaxin Shi, Meng Xu, Fuhao Wang, Jinling Lv, Jiaman Sun, Weiyi Niu, Zihan Liu, Li Li, Fufeng Liu, Xiangming Wang   +12 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Ischaemic stroke as the initial presentation of a pheochromocytoma associated with neurofibromatosis type 1

Asian Journal of Internal Medicine
Pheochromocytoma is a rare but well-recognised manifestation of neurofibromatosis type 1 (NF1). Ischaemic stroke has been rarely reported in patients with pheochromocytoma. It can be due to either hypertension or vasospasm. A 33-year-old woman presented
S. W. Gnanathayalan, B. M. S. Fernando, U. Bulugahapitiya   +2 more
doaj   +1 more source