Results 41 to 50 of about 74,986 (277)

Pheochromocytoma – clinical manifestations, diagnosis and current perioperative management [PDF]

, 2019
Pheochromocytoma is a neuroendocrine tumor characterized by the excessive production of catecholamines (epinephrine, norepinephrine, and dopamine). The diagnosis is suspected due to hypertensive paroxysms, associated with vegetative phenomena, due to the
Bratu, Ovidiu G, Diaconu, Camelia C, Gaman, Mihnea A, Manea, Maria, Marcu, Dragos R, Pantea Stoian, Anca, Stanescu, Ana M   +6 more
core   +1 more source

Purification of alpha-toxin from Staphylococcus aureus and application to cell permeabilization [PDF]

, 1987
Crude alpha-toxin was produced by Staphylococcus aureus, strain Wood 46. The amount of exotoxin was monitored during growth and all subsequent purification steps by determination of its hemolytic activity against rabbit erythrocytes.
Ahnert-Hilger, Ahnert-Hilger, Bader, Bhakdi, Bhakdi, Bhakdi, Cassidy, Dunn, Füssle, Laemmli, Lowry, McEwen, Möllby, Reynolds, Thelestam, Wadström, Wilson   +16 more
core   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Succinate dehydrogenase (SDH)-deficient renal carcinoma:a morphologically distinct entity: a clinicopathologic series of 36 tumors from 27 patients [PDF]

, 2014
Succinate dehydrogenase (SDH)-deficient renal carcinoma has been accepted as a provisional entity in the 2013 International Society of Urological Pathology Vancouver Classification.
Belinsky, Cascon, Cascon, Chou, Dwight, Dwight, Eng, Fairchild, Fishbein, Fleming, Gaal, Gill, Gill, Gill, Gill, Gill, Gill, Gill, Gill, Gimm, Henderson, Housley, Janeway, Jasperson, Korpershoek, Malinoc, Miettinen, Miettinen, Miettinen, Neumann, Ni, Oudijk, Paik, Papathomas, Ricketts, Ricketts, Said-Al-Naief, Schimke, Solis, Srigley, Srirangalingam, Srirangalingam, van Nederveen, van Nederveen, Vanharanta, Wagner, Xekouki   +46 more
core   +3 more sources

Massive pheochromocytoma [PDF]

Clinical Case Reports, 2020
AbstractComplications of pheochromocytoma, such as hypertensive emergency, can be critical. Clinicians should recognize that pheochromocytoma is not uncommon in patients with large adrenal tumors, and screening should be undertaken prior to any intervention.
Terumitsu Anai, Kosuke Oka, Yuya Yokota, Yoshito Nishimura, Hideharu Hagiya, Fumio Otsuka   +5 more
openaire   +3 more sources

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

From Childhood Migraine Headache to Pheochromocytoma

Case Reports in Endocrinology, 2014
Pheochromocytoma may have multiple clinical manifestations including paroxysmal hypertension, tachycardia, sweating, nausea, and headache (Phillips et al., 2002). Migraine has some of the manifestations seen with pheochromocytoma.
Y. M. Hazimeh, M. Luidens, M. E. Ehlers, V. Sharma   +3 more
doaj   +1 more source

Pheochromocytoma: A single-center 20-year experience

Urological Science, 2019
Objective: Pheochromocytomas are catecholamine-producing neuroendocrine tumors arising from chromaffin cells of the adrenal medulla or extra-adrenal paraganglia. There is no large-scale study in Taiwan at present.
Lung-Feng Cheng, Shih-Che Tseng, Chia-Cheng Yu, Jen-Tai Lin, Jeng-Yu Tsai, I-Hsuan Chen, Yin-Shen Chen   +6 more
doaj   +1 more source

Pheochromocytoma crisis [PDF]

Clinical Case Reports, 2013
Key Clinical MessageAdrenergic crisis induced by a pheochromocytoma leads to life‐threatening catecholamine‐induced hemodynamic disturbances. Successful treatment of a pheochromocytoma crisis demands prompt diagnosis, vigorous pharmacological therapy and emergent tumor removal, if the patient continues to ...
Tschuor, Christoph, Sadri, Helen, Clavien, Pierre-Alain   +2 more
openaire   +2 more sources

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source