Results 71 to 80 of about 47,675 (242)

Pheochromocytoma [PDF]

open access: yesCancer, 1972
S, Warren, R N, Chute
openaire   +4 more sources

Bilateral primary adrenal lymphoma

open access: yes
Journal of General and Family Medicine, EarlyView.
Rio Shimizu, Shogo Shirota
wiley   +1 more source

PI5P4K inhibitors: promising opportunities and challenges

open access: yesThe FEBS Journal, EarlyView.
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi   +16 more
wiley   +1 more source

Systemic Steroid Application Caused Sudden Death of a Patient with Sudden Deafness

open access: yesCase Reports in Otolaryngology, 2013
A 63-year-old man, who was diagnosed with sudden sensorineural hearing loss (SSHL), showed severe hypertension 10 hours after prednisolone administration. Subsequently, the patient suddenly died due to pulmonary edema.
Eriko Ogino-Nishimura   +4 more
doaj   +1 more source

The clinical roles of generalists in Japan: A descriptive model of problem setting and problem‐solving

open access: yes
Journal of General and Family Medicine, EarlyView.
Masayuki Amano   +2 more
wiley   +1 more source

Allosteric modulation of protein kinase A in individuals affected by NLPD‐PKA, a neurodegenerative disease in which the PRKAR1B L50R variant is expressed

open access: yesThe FEBS Journal, EarlyView.
In healthy neurons, Protein kinase A (PKA) forms a tetrameric holoenzyme enabling precise allosteric regulation. We characterized a novel neurodegenerative disease, neuronal loss, and parkinsonism driven by PRKAR1B mutation (NLPD‐PKA), demonstrating disrupted holoenzyme assembly, reduced cooperativity, and increased catalytic subunit nuclear ...
Tal Benjamin‐Zukerman   +13 more
wiley   +1 more source

PARP Inhibitors in Genitourinary Cancer: A New Paradigm Beyond Prostate Cancer

open access: yesInternational Journal of Urology, EarlyView.
ABSTRACT Alterations in the homologous recombination repair genes, such as BRCA1 and BRCA2, are prevalent in various cancers, presenting a unique opportunity to develop synthetic lethal strategies that target homologous recombination deficiency (HRD).
Yohei Okuda   +8 more
wiley   +1 more source

Composite pheochromocytoma with a malignant peripheral nerve sheath tumor: Case report and review of the literature

open access: yesAsian Journal of Surgery, 2016
Adrenal tumors with more than one cellular component are uncommon. Furthermore, an adrenal tumor composed of a pheochromocytoma and a malignant peripheral nerve sheath tumor is extremely rare.
Takeshi Namekawa   +9 more
doaj   +1 more source

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