Maturation of Pseudo-Nucleus Compartment in P. aeruginosa, Infected with Giant phiKZ Phage [PDF]
The giant phiKZ phage infection induces the appearance of a pseudo-nucleus inside the bacterial cytoplasm. Here, we used RT-PCR, fluorescent in situ hybridization (FISH), electron tomography, and analytical electron microscopy to study the morphology of ...
Yana A. Danilova +5 more
doaj +3 more sources
Characterization of two related Erwinia myoviruses that are distant relatives of the PhiKZ-like Jumbo phages. [PDF]
Bacteriophages are a major force in the evolution of bacteria due to their sheer abundance as well as their ability to infect and kill their hosts and to transfer genetic material.
Daniel K Arens +14 more
doaj +4 more sources
This work deals with evaluation of key properties of some fluorescent proteins (FPs) in order to use them for observation of redistributing the target proteins between the cytoplasm and pseudonucleus forming in bacterial cell infection by bacteriophage
Antonova Daria +4 more
doaj +3 more sources
Differential Effect of Newly Isolated Phages Belonging to PB1-Like, phiKZ-Like and LUZ24-Like Viruses against Multi-Drug Resistant Pseudomonas aeruginosa under Varying Growth Conditions [PDF]
In this study, we characterize three phages (SL1 SL2, and SL4), isolated from hospital sewage with lytic activity against clinical isolates of multi-drug resistant Pseudomonas aeruginosa (MDR-PA).
Simone Latz +5 more
doaj +4 more sources
Structure of the Bacteriophage PhiKZ non-Virion RNA Polymerase [PDF]
AbstractBacteriophage ΦKZ is the founding member of a family of massive bacterial viruses. It is considered to have therapeutic potential as its host,Pseudomonas aeruginosa, is an opportunistic, intrinsically antibiotic resistant, pathogen that kills tens of thousands worldwide each year.
Natàlia de Martín Garrido +9 more
openaire +7 more sources
Nucleus-forming jumbophage PhiKZ therapeutically outcompetes non-nucleus-forming jumbophage Callisto. [PDF]
With the recent resurgence of phage therapy in modern medicine, jumbophages are currently under the spotlight due to their numerous advantages as anti-infective agents. However, most significant discoveries to date have primarily focused on nucleus-forming jumbophages, not their non-nucleus-forming counterparts. In this study, we compare the biological
Naknaen A +4 more
europepmc +4 more sources
Correction to 'Structure of the bacteriophage PhiKZ non-virion RNA polymerase'. [PDF]
de Martín Garrido N +9 more
europepmc +3 more sources
Aeromonas salmonicida is the causative agent of septicemia in fish, and it is associated with significant economic losses in the aquaculture industry. While piscine Aeromonas infections are mainly treated with antibiotics, the emergence of resistance in ...
Vera Morozova +8 more
doaj +1 more source
Assessing the transcriptional landscape of Pseudomonas phage 201ϕ2-1: Uncovering the small regulatory details of a giant phage. [PDF]
Transcriptomic studies on jumbo phages have been limited. From a phage biology perspective, insights into their transcriptome will improve our understanding of how they regulate their infection cycle. Moreover, phage transcriptomic studies are valuable for sourcing regulatory elements which can be exploited in microbial synthetic biology to tune gene ...
Poppeliers J +5 more
europepmc +2 more sources
Ribonucleases are crucial players of the post‐transcriptional regulation. Here are represented specific cases of ribonuclease‐RNA or exoribonuclease‐endoribonuclease interactions that have been uncovered so far in Pseudomonas. Summary The development of synthetic biology has brought an unprecedented increase in the number molecular tools applicable ...
Patrícia Apura +3 more
wiley +1 more source

