Results 61 to 70 of about 42,888 (218)

Philadelphia chromosome positive childhood acute lymphoblastic leukemia [PDF]

, 1980
JR Priest, Robison Ll, RW McKenna, LL Lindquist, PI Warkentin, Tucker W. LeBien, WG Woods, JH Kersey, PF Coccia, ME Jr Nesbit   +9 more
openalex   +3 more sources

Fluorescent in-situ hybridization (FISH) for BCR/ABL in chronic myeloid leukemia after bone marrow transplantation

São Paulo Medical Journal, 2001
CONTEXT: Identification of Philadelphia chromosome or BCR/ABL gene rearrangement in chronic myeloid leukemia is important at diagnosis as well as after treatment.
Maria de Lourdes Lopes Ferrari Chauffaille, José Salvador Rodrigues Oliveira, Maura Romeo, José Kerbauy   +3 more
doaj   +1 more source

Growth Charts for Children With Beckwith–Wiedemann Spectrum

American Journal of Medical Genetics Part A, Volume 197, Issue 8, August 2025.
ABSTRACT Beckwith–Wiedemann spectrum (BWSp) is an overgrowth disorder caused by (epi)genetic alterations in chromosome 11p15. This study aimed to develop BWSp‐specific growth charts and explore genotype/phenotype correlations with respect to growth. Heights, weights, and head circumferences were retrospectively collected from 581 individuals with BWSp ...
Saskia M. Maas, Peter Lauffer, Guido Cocchi, Madison DeMarchis, Andrew M. George, Alessandro Mussa, Francesco Pellegrino, Alexander M. J. Spaans, Emma C. van den Brink, Jan M. Wit, Leonie A. Menke, Jennifer M. Kalish   +11 more
wiley   +1 more source

Cannabis Extract Treatment for Terminal Acute Lymphoblastic Leukemia with a Philadelphia Chromosome Mutation

Case Reports in Oncology, 2013
Acute lymphoblastic leukemia (ALL) is a cancer of the white blood cells and is typically well treated with combination chemotherapy, with a remission state after 5 years of 94% in children and 30-40% in adults. To establish how aggressive the disease is,
Yadvinder Singh, Chamandeep Bali
doaj   +1 more source

S‐GMAS: Genome‐Wide Mediation Analysis With Brain Subcortical Shape Mediators

Human Brain Mapping, Volume 46, Issue 11, 01 August 2025.
Using the ADNI Corpus Callosum (CC) shape data, we proposed a genome‐wide mediation analysis framework involving high‐dimensional genetic exposures and shape mediators and successfully identified distinct genetic‐to‐clinical outcome pathways mediated through the CC in Alzheimer's Disease, revealing varying spatial causal effect patterns for different ...
Shengxian Ding, Rongjie Liu, Anuj Srivastava, Richard S. Nowakowski, Li Shen, Paul M. Thompson, Heping Zhang, Chao Huang   +7 more
wiley   +1 more source

Translation of the Philadelphia chromosome into therapy for CML [PDF]

Blood, 2008
AbstractThroughout its history, chronic myeloid leukemia (CML) has set precedents for cancer research and therapy. These range from the identification of the first specific chromosomal abnormality associated with cancer to the development of imatinib as a specific, targeted therapy for the disease.
openaire   +2 more sources

Detection of PTEN Mutations in Fine Needle Aspiration Biopsies of Indeterminate Thyroid Nodules: Impact on Diagnosis and Prognosis

Head &Neck, Volume 47, Issue 8, Page 2145-2151, August 2025.
ABSTRACT Background Data connecting PTEN mutations with thyroid cancer risk for indeterminate nodules remain limited due to the rare nature of these mutations. The aim of this study was to determine the relationship between PTEN mutations identified in cytologically indeterminate nodules and final pathology and clinical outcomes.
Lauren E. Schlegel, Madelaine Brill‐Edwards, Zi‐Xuan Wang, Christopher McNair, Stacey Gargano, Elizabeth Cottrill   +5 more
wiley   +1 more source

The Distribution of the Philadelphia Chromosome in Patients with Chronic Myelogenous Leukemia [PDF]

, 1963
JACQUELINE WHANG, Emil Frei, J. H. Tjio, Paul P. Carbone, George Brecher   +4 more
openalex   +1 more source

Dasatinib and Prednisolone Induction Therapy for a Case of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia with Dilated Cardiomyopathy Accompanied by Life-Threatening Ventricular Tachycardia

Case Reports in Hematology, 2017
A 56-year-old man being treated for dilated cardiomyopathy presented with epigastralgia. He was diagnosed with ventricular tachycardia and Philadelphia chromosome-positive acute lymphoblastic leukemia. After treating incessant ventricular tachycardia, we
Mitsutaka Nishimoto, Hirohisa Nakamae, Kana Matsumoto, Kunihiko Morita, Yuki Koga, Dai Momose, Masayuki Hino   +6 more
doaj   +1 more source

Prediction of B/T Subtype and ETV6–RUNX1 Translocation in Pediatric Acute Lymphoblastic Leukemia by Deep Learning Analysis of Giemsa‐Stained Whole Slide Images of Bone Marrow Aspirates

Pediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Background Accurate determination of B/T‐cell lineage and the presence of the ETV6–RUNX1 translocation is critical for diagnosing acute lymphoblastic leukemia (ALL), as these factors influence treatment decisions and outcomes. However, these diagnostic processes often rely on advanced tools unavailable in low‐resource settings, creating a need
Arkadi Piven, Gil Shamai, Sarah Elitzur, Galit Pinto Berger, Yoav Binenbaum, Ron Kimmel, Ronit Elhasid   +6 more
wiley   +1 more source