Results 71 to 80 of about 76,188 (198)

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, Volume 16, Issue 8, Page 1509-1526, August 2026.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

BLINATUMOMAB IN THE THERAPY OF ACUTE B-LYMPHOID LEUKEMIA

Mediterranean Journal of Hematology and Infectious Diseases
Blinatumomab, a CD19-CD3 bispecific T cell engager (BiTE), has two recombinant single-chain variable fragments that temporarily link CD3+ T cells and CD19+ B cells, leading to the T cell-mediated lysis of neoplastic B cells.
Ugo Testa, Elvira Pelosi, Germana Castelli, Patrizia Chiusolo   +3 more
doaj   +1 more source

Genomic Contributors to Congenital Diaphragmatic Hernia: Results of Exome Sequencing in 560 Probands and Cross Reference of Findings in an Independent Cohort

American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1821-1831, August 2026.
ABSTRACT There is a strong genetic contribution to the etiology of congenital diaphragmatic hernia (CDH). This study evaluated genetic testing results and diagnostic yield for fetuses and children with CDH. This was a retrospective cohort study of exome sequencing (ES) performed at GeneDx for fetuses and children ≤ 18 years of age with CDH compared ...
Justin Blair, Kevin Carratu, Natalie E. Rintoul, Holly L. Hedrick, William H. Peranteau, Catherine M. Avitabile, Kirsty McWalter, Paul Kruszka, Ian D. Krantz, K. Taylor Wild   +9 more
wiley   +1 more source

Stratification by a polygenic risk score of common variation aids in Alzheimer's disease rare variant discovery

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION We utilized an Alzheimer's disease (AD) polygenic risk score (PRS) to discover associations with novel rare variants (RVs). METHODS PRSs for European ancestry (EA) participants of the Alzheimer's Disease Sequencing Project were calculated using summary statistics from a large genome‐wide association study.
Oluwatosin Olayinka, John J. Farrell, Congcong Zhu, Zainab Khurshid, Alzheimer's Disease Sequencing Project, Eden R. Martin, William S. Bush, Margaret A. Pericak‐Vance, Li‐San Wang, Gerard D. Schellenberg, Jonathan L. Haines, Kathryn L. Lunetta, Xiaoling Zhang, Lindsay A. Farrer   +13 more
wiley   +1 more source

Chronic myeloid leukemia (CML): prognostic factors and survival analysis

São Paulo Medical Journal
The prognostic value of different factors upon diagnosis of CML was analysed in 45 Philadelphia (Ph1)-positive patients. The median survival was 48 months.
Gisele Wally Braga, Maria de Lourdes Lopes Ferrari Chauffaille, José Eduardo Cajado Moncau, Elizabeth Xisto Souto, Maria Regina Regis Silva, José Kerbauy   +5 more
doaj   +1 more source

What's Your Diagnosis? A Case of Extreme Thrombocytosis in a Dog

Veterinary Clinical Pathology, EarlyView.
Stephanie F. Anderson, King Long Hannah Lee, Megan Dietz, Sarah Guess, Laura White, Mara S. Varvil   +5 more
wiley   +1 more source

A Therapeutic Dilemma: Catastrophic ST‐Elevation Myocardial Infarction Following Antiplatelet Therapy Interruption in a Patient With JAK2‐Positive Polycythemia Vera

Clinical Case Reports, Volume 14, Issue 8, August 2026.
Premature interruption of dual antiplatelet therapy in a patient with polycythemia vera and clinically suspected acquired von Willebrand syndrome triggered catastrophic recurrent stent thrombosis, whereas perioperative bridging with eptifibatide enabled safe surgery. ABSTRACT Polycythemia vera is associated with a thrombotic–hemorrhagic paradox.
Behrouz zarei, Amirhossein Rezaei Latifi, Mohammad Salari   +2 more
wiley   +1 more source

Impact of Atrial Fibrillation on the Risk of Thrombosis and Bleeding for Patients With Polycythemia Vera and Essential Thrombocytosis in the Real World

American Journal of Hematology, Volume 101, Issue 9, Page 2463-2468, September 2026.
Rodrigo Ortega Perez, Luis Manuel Domínguez Rodríguez, Francisca Ferrer‐Marín, Beatriz Cuevas Ruíz, Clara Martínez Valverde, Patricia Vélez Tenza, María Isabel Mata Vázquez, Adrián Segura Díaz, María Laura Fox, Elvira Mora, Manuel Mateo Pérez Encinas, Mercedes Gasior Kabat, Gonzalo Carreño‐Tarragona, Rafael Andrés del Orbe, Gonzalo Caballero‐Navarro, Elena Magro Mazo, Ana Pardo Sanz, José Luis Zamorano Gómez, Alberto Álvarez Larrán, Valentín Garcia‐Gutierrez   +19 more
wiley   +1 more source

Acute and Chronic Leukemia in Sub‐Saharan Africa: A Systematic Review

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background The four primary subgroups of leukemia include chronic myeloid leukemia (CML), acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), and chronic lymphocytic leukemia (CLL). Very little is known about the regional variation of leukemia and subtypes in sub‐Saharan Africa (SSA).
Allwell A. Ayirebi, Stephen Twumasi, Linda K. Olaga, Benedict Sackey, Daniel N. M. Antonio, Richard O. Ansah, Eugene A. Ansah, John A. Sah, Enoch O. Anto, Yvonne Anang‐Quartey, Antoinette Koomson, Angela Opoku, Godfred A. Donkor, Paulina Duah, Ama G. Boadu, Samuel Essien‐Baidoo, Wina I. O. Boadu, Lilian A. Boateng   +17 more
wiley   +1 more source

PB1757: VARIANT PHILADELPHIA CHROMOSOME IN ALL

HemaSphere, 2022
N. Bouayed Abdelmoula, B. Abdelmoula, A. Sbai, M. Ben ayed, S. Aloulou   +4 more
doaj   +1 more source