Results 91 to 100 of about 80,480 (249)

Dasatinib and Prednisolone Induction Therapy for a Case of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia with Dilated Cardiomyopathy Accompanied by Life-Threatening Ventricular Tachycardia

Case Reports in Hematology, 2017
A 56-year-old man being treated for dilated cardiomyopathy presented with epigastralgia. He was diagnosed with ventricular tachycardia and Philadelphia chromosome-positive acute lymphoblastic leukemia. After treating incessant ventricular tachycardia, we
Mitsutaka Nishimoto, Hirohisa Nakamae, Kana Matsumoto, Kunihiko Morita, Yuki Koga, Dai Momose, Masayuki Hino   +6 more
doaj   +1 more source

Ancient Migratory Events in the Middle East: New Clues from the Y-Chromosome Variation of Modern Iranians

, 2012
Knowledge of high resolution Y-chromosome haplogroup diversification within Iran provides important geographic context regarding the spread and compartmentalization of male lineages in the Middle East and southwestern Asia.
Baharak Hooshiar Kashani, Achilli Alessandro, Mohammad Hossein Sanati (150527), Massoud Houshmand, Mohammad Hossein Sanati, Houshmand M, Torroni Antonio, Viola Grugni, Al-Zahery Nadia, Francesca Gandini (150515), Anna Olivieri, Nadia Al-Zahery (150508), Sanati, Mohammad Hossein, Antonio Torroni (42164), Gandini, Francesca, Vincenza Battaglia (150500), Battaglia Vincenza, Torroni, Antonio, Massoud Houshmand (150522), Hooshiar Kashani, Baharak, Houshmand, Massoud, Grugni Viola, Olivieri Anna, Grugni, Viola, Ornella Semino (150533), Hossein Sanati M, Baharak Hooshiar Kashani (144912), Hooshiar Kashani Baharak, Anna Olivieri (144908), Sanati Mohammad Hossein, Al-Zahery, Nadia, Nadia Al-Zahery, Parolo Silvia, Vincenza Battaglia, Antonio Torroni, Ornella Semino, Gandini Francesca, Battaglia, Vincenza, Houshmand Massoud, Parolo, Silvia, Achilli, Alessandro, Semino, Ornella, Francesca Gandini, Alessandro Achilli (42157), Semino Ornella, Silvia Parolo, Viola Grugni (150495), Alessandro Achilli, Olivieri, Anna, Silvia Parolo (150504)   +49 more
core   +1 more source

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges, Kelly A. Duffy, Sara McDonough, Evelyn Kurpiewski, R. Jennifer Randall, Allison Barz Leahy, Haley M. Newman, Joyce P. Lee, Stephen P. Hunger, Anne F. Reilly, David T. Teachey, Susan R. Rheingold, Daniel J. Zheng   +12 more
wiley   +1 more source

Patients in Focus: What's Relevant for Chronic Myeloid Leukaemia and Philadelphia Chromosome-Positive Acute Lymphoblastic Leukaemia?

, 2017
This symposium was dedicated to discussing BCR-ABL-positive chronic myeloid leukaemia (CML) and Philadelphia-positive acute lymphoblastic leukaemia (Ph+ALL).
Eduardo Olavarria, Delphine Rea, Giovanni Martinelli, Hugues de Lavallade, Michele Baccarani   +4 more
core  

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Molecular characterization and predictors of relapse in patients with Ph + ALL after frontline ponatinib and blinatumomab

Journal of Hematology & Oncology
Background Several studies have suggested that chemotherapy-free regimens consisting of blinatumomab and a BCR::ABL1 tyrosine kinase inhibitor are highly effective in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph + ALL).
Nicholas J. Short, Hagop Kantarjian, Ken Furudate, Nitin Jain, Farhad Ravandi, Omer Karrar, Sanam Loghavi, Lewis Nasr, Fadi G. Haddad, Jayastu Senapati, Rebecca Garris, Koichi Takahashi, Elias Jabbour   +12 more
doaj   +1 more source

Philadelphia chromosome

, 1997
Philadelphia ...

core  

Philadelphia chromosome-positive acute lymphoblastic leukemia in childhood

, 2011
In pediatric patients with acute lymphoblastic leukemia (ALL), the Philadelphia chromosome translocation is uncommon, with a frequency of less than 5%.
Hong Hoe Koo
core   +1 more source

Drugs that act on both G protein‐coupled receptors (GPCRs) and kinases: potentiation of effects, side effects and general aspects of drug pleiotropy

British Journal of Pharmacology, Volume 183, Issue 13, Page 3471-3483, July 2026.
Abstract Background A drug designed for a specific target often interacts with multiple targets, either unintentionally or as part of its intended mechanism of action. This has been called pharmacological pleiotropy or polypharmacology. There are key endogenous ligands such as ATP, GABA and glutamate that act on various proteins in humans. Furthermore,
Hampus Ljunggren, Aleksandr Sokolov, Flavio Ballante, Robert Fredriksson, Francisco Lagunas‐Rangel, Alexander S. Hauser, Stefan Knapp, Jörgen Jonsson, Helgi B. Schiöth   +8 more
wiley   +1 more source

Cognitive and neurodevelopmental disorders in spinal muscular atrophy type I at the time of disease‐modifying therapies

Developmental Medicine &Child Neurology, Volume 68, Issue 7, Page 909-915, July 2026.
Abstract After treatment with new disease‐modifying therapies, cognitive and neurodevelopmental aspects have been observed in individuals with spinal muscular atrophy (SMA). Emerging evidence suggests that children with SMA type 1 may experience cognitive, language, and behavioural delays, with reported rates of neurodevelopmental difficulties ranging ...
Giorgia Coratti, Bianca Buchignani, Eugenio Mercuri   +2 more
wiley   +1 more source