Results 91 to 100 of about 76,188 (198)

Meta‐Analysis of Imatinib Resistance in Chronic Myeloid Leukemia due to BIM Gene Deletion and Single Nucleotide Polymorphisms Reveals Ethnic Variations in Prevalence

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Background and Aim Deletion and single nucleotide polymorphisms in the BIM gene have been proposed as a potential contributor of intrinsic resistance to imatinib in patients with chronic myeloid leukemia (CML). Individual studies, particularly in East Asian population, have reported higher frequency of these gene variants and have suggested ...
Abhinav Bhattarai, Dimitri Kountouris, Sanjit Sah, Rachana Mehta, Ranjit Sah   +4 more
wiley   +1 more source

Central nervous system involvement and relapse in adult acute lymphoblastic leukaemia—a population‐based analysis in 2007–2022

British Journal of Haematology, Volume 209, Issue 2, Page 589-600, August 2026.
Summary Central nervous system (CNS) involvement and relapse remains a clinical challenge in the management of acute lymphoblastic leukaemia (ALL), and studies among adult ALL patients are scarce. We identified all adult ALL patients in Sweden between 2007 and 2022 (n = 838) from the population‐based ALL register and evaluated factors associated with ...
Erik Boberg, Anna Lübking, Emma Bergfelt Lennmyr, Caroline E. Dietrich, Joel Joelsson, Karin E. Smedby, Tove Wästerlid, Helene Hallböök   +7 more
wiley   +1 more source

Clinical Characterization of Patients With 5q Spinal Muscular Atrophy Types 2 and 3 in Brazil: A Cross‐Sectional Observational Study

Clinical Genetics, Volume 110, Issue 2, Page 172-188, August 2026.
This study describes the clinical heterogeneity of Brazilian patients with 5q spinal muscular atrophy types 2 and 3, highlighting prolonged diagnostic delays and the impact of disease duration on motor function. Early genetic diagnosis and access to multidisciplinary care are crucial to preserve functional outcomes.
Elice Carneiro Batista, Edmar Zanoteli, Henrique Andrade R. Fonseca, Graziela Jorge Polido, Jonas Alex Morales Saute, Adriana Banzzatto Ortega, Marcondes Cavalcante França Junior, Acary Souza Bulle Oliveira, Paulo Victor Sgobbi de Souza, Juliana Gurgel Giannetti, André Luiz Santos Pessoa, Alexandra Prufer de Queiroz Campos Araújo, Mário Fritsch Toros Neves, Raquel Tavares Boy da Silva, Frederico Monfardini, Gustavo Prado dos Santos, Bruna dos Santos Sampaio, Diogo Fagundes Moia, Fernando Galan Júnior, Luciana Pereira Almeida de Piano, Camila Santos Nascimento de Albuquerque, Flávia Miranda Duarte, Viviane Aparecida Rodrigues Sant’Anna, Mariane Pereira, Jomenica de Bortoli Livramento, Ronaldo Vicente Pereira Soares, Denison Alves Pedrosa, Vanessa Teich, Luiz Vicente Rizzo, Otávio Berwanger, João Brainer Clares de Andrade, Gisele Sampaio Silva   +31 more
wiley   +1 more source

Cognitive and Demographic Associations of Dementia‐Related Behavioural Changes in Adults With an Intellectual Disability: Findings From the IDS‐TILDA Study

Journal of Intellectual Disability Research, Volume 70, Issue 8, Page 871-880, August 2026.
ABSTRACT Background Individuals with intellectual disabilities (ID) are at an increased risk of developing dementia. Early detection is essential for providing appropriate support, yet identifying dementia‐related changes is challenging due to pre‐existing cognitive impairments.
Marie‐Joelle Beaudoin, Pavithra Pavithra, Mary McCarron, Philip McCallion, Antoinette O'Connnor, Sean Kennelly, Shoumitro Deb, Eimear McGlinchey   +7 more
wiley   +1 more source

A case of leukemia cutis showing annular erythema during the course of Philadelphia chromosome‐positive acute B‐lymphoblastic leukemia

Clinical Case Reports
Key Clinical Message We report a case of leukemia cutis showing annular erythema during the course of Philadelphia chromosome‐positive acute B‐lymphoblastic leukemia. The annular appearance may be developed by immunomodulatory effects of blinatumomab.
Hizuru Tomita, Yoshimasa Nobeyama, You Sakayori, Rika Matsumoto, Satomi Chujo, Hikaru Suzuki, Akihiko Asahina   +6 more
doaj   +1 more source

Global Prevalence of Oral Potentially Malignant Disorders: An Updated Systematic Review and Meta‐Analysis

Journal of Oral Pathology &Medicine, Volume 55, Issue 7, Page 747-754, August 2026.
ABSTRACT Background Oral potentially malignant disorders (OPMDs) represent a diverse group of mucosal disorders with varying risks of progression to oral cancer. Objective This updated systematic review (SR) and meta‐analysis (MA) estimated the global prevalence of histopathologically confirmed OPMDs, excluding oral lichen planus and lichenoid lesions.
Nicole Lonni, Tulio Silva Rosa, Camilla Kammer Pereira, Gilberto Melo, Saman Warnakulasuriya, Eliete Neves Silva Guerra, Elena Riet Correa Rivero   +6 more
wiley   +1 more source

Philadelphia Chromosome [PDF]

, 2020
openaire   +1 more source

Philadelphia Chromosome-Positive B-cell Acute Lymphoblastic Leukemia: A Case Report. [PDF]

Cureus
Izadian Bidgoli A, Gomez Veliz A, Yazdanpanah S, Saavedra G, Pina A, Rame G.   +5 more
europepmc   +1 more source

Asciminib in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: A Case Series and Review of Emerging Evidence. [PDF]

Hematol Rep
Mohammed Saleh MF, Nasiri A, Abdrabou AK, Samarkandi H, Saad A, Aljurf M, Hanbali A, Alahmari A.   +7 more
europepmc   +1 more source

Durable MRD-Negative Remission With Blinatumomab and Venetoclax in Heavily Pretreated Relapsed/Refractory Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia. [PDF]

EJHaem
Qadir MS, Farooq S, Jamy O.
europepmc   +1 more source