Results 71 to 80 of about 6,802 (260)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Implications of corporate philanthropy for social responsibility in the textile industry [PDF]
Tekstilna industrija, 2020 The subject of this paper is the implications of corporate philanthropy in the textile industry in a contemporary business environment. Due to the importance of corporate philanthropy for corporate social responsibility, the paper discusses its role in ...
Pantelić Ivan +2 more
doaj
Chinese Philanthropic Response to COVID-19 in the Malaysian Context
, 2021 The novel human coronavirus disease COVID-19, first reported in Wuhan, China in December 2019 and subsequently spread worldwide, has evolved into a global health and socioeconomic crisis so serious it has been declared a pandemic by the World Health Organization.
Lee, Kenneth Tze Wui +4 more
openaire +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Civilizar, 2013 The tendency of organizations is to achieve positioning and legitimacy through strategies of corporate social responsibility (CSR). This article focuses on the analysis of CSR practices and it seeks, through a business case, to define a method to examine
Diana Carolina Peláez Villada +1 more
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Korzyści z wprowadzenia zasad społecznej odpowiedzialności biznesu w przedsiębiorstwie
Przedsiębiorczość - Edukacja, 2008 The corporate social responsibility a completely new idea until quite recently becomesmore and more indispensable in the company strategy. It is so because nowadays CSR isassociated with a series of benefits.The paper presents the very idea of social
Kornelia Bem-Kozieł
doaj
IBDA': Jurnal Kebudayaan IslamCOVID-19 has impacted people’s lives worldwide as a global pandemic. It is a shocking health issue and generates other economic and societal problems. With its many citizens, Indonesia faces limitations in dealing with this pandemic.
Nina Mariani Noor +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source