Results 51 to 60 of about 87,118 (310)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Community Foundations and International Giving: Opportunities for Global Engagement [PDF]
, 2006 Outlines discussions from two convenings on U.S. community foundations' role in international giving, the resources and strategies needed to better respond to donors' interests in global giving, and recommendations for research and special ...
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The Philanthropic Landscape in the United States: A Topology of Trends [PDF]
, 2013 Over the last decade, the field of philanthropy has been in a constant state of evolution. New wealth has brought new philanthropists into the field, many seeking to apply their business acumen to their philanthropic work.
Sandra Bass
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Kurumsal Sosyal Sorumluluğun Satın Alma Niyeti Üzerindeki Etkisi: İstanbul İlinde Bir Araştırma
İstanbul Gelişim Üniversitesi Sosyal Bilimler Dergisi, 2017 Bu çalışmanın amacı, kurumsal sosyal sorumluluğun satın alma niyeti üzerindeki etkisinin belirlenmesidir. Bu amaçla tasarlanan araştırmada ekonomik, yasal, etik ve gönüllü sosyal sorumluluk ele alınmış, bu boyutlarla birlikte satın alma niyetini ölçen ...
İlknur Bilgen, Gülsüm Vezir Oğuz
doaj +1 more source
The Social Responsibility among Higher Education Students
Education Sciences, 2020 The aim of this research is to emphasize the importance of education for the philanthropic responsibilities of students. The basic term of the explanatory research is corporate social responsibility, adapted for higher education institutions—the ...
Emese Beáta Berei
doaj +1 more source
Creating a Culture of Philanthropy: Three Things to Keep in Mind [PDF]
, 2017 A culture of philanthropy is necessary for a nonprofit to be successful in 2016. Resources and funds are not so bountiful as they were in the past. Every nonprofit is different and has a different audience, but in general, there are three items to keep ...
Zirkle, Keith W.
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
, 2013 The Philanthropy Insights Report is based on research aimed at furthering the overall understanding of philanthropy in South Africa.The report was written in collaboration with various philanthropic experts from different fields.The different subsections
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