Results 161 to 170 of about 94,585 (264)

Click'n ROPISA: One‐Pot Synthesis of Ultrabright Fluorescent Nanoparticles Made of Polypeptides

open access: yesAngewandte Chemie, EarlyView.
Self‐assembly and fluorophore conjugation proceed rapidly in a one‐pot “Click'n ROPISA” process, yielding intensely fluorescent polypeptide nanoparticles with tunable visible emission. High dye loading enables efficient energy transfer and single‐particle visualization, while the straightforward synthesis provides versatile access to bright ...
Amin El Jarroudi Hammou   +7 more
wiley   +2 more sources

Five Issues of Artificial Intelligence in Science: Sailing the Ship of Theseus

open access: yesAnnals of Neurology, EarlyView.
Artificial intelligence (AI) is becoming part of the working infrastructure of academic medicine. Because grants convert scientific ideas into protected time, infrastructure, and institutional priority, they provide a revealing test case for AI's effects on biomedicine. Five issues are emerging: language, agency, review, doership, and identity.
S. Thomas Carmichael
wiley   +1 more source

Ionic Liquid Electrolytes for Extreme Temperature Conditions: Challenges and Perspective

open access: yesAngewandte Chemie, EarlyView.
Ionic liquids (ILs) have gained great attention as safe electrolyte components in recent years. This review elucidates the temperature effects on IL‐based electrolytes from molecular configurations, physicochemical properties, and interfacial chemistry, raises the challenges and design strategies operating at low‐ and HT, providing valuable guidance ...
En Xie   +11 more
wiley   +2 more sources

Distribution of Big Tau Isoforms in the Human Central and Peripheral Nervous System

open access: yesAnnals of Neurology, EarlyView.
Objective Tau is widely studied in neurodegeneration, yet most work has focused on canonical brain tau isoforms. A longer isoform, “big tau,” produced by inclusion of exon 4a, is expressed in the peripheral nervous system (PNS) and central nervous system (CNS) regions.
Rama Krishna Koppisetti   +17 more
wiley   +1 more source

Tunable Oxygen Connectivity in Carbaporphyrinoid Polymers on Metal Surfaces

open access: yesAngewandte Chemie, EarlyView.
Hydroxyl‐functionalized dicarbaporphyrinoid polymers synthesized on Au(111) enable tunable oxygen‐mediated connectivity under UHV conditions. Thermal activation yields one‐dimensional hydroxyl‐terminated polymers that can selectively evolve into either covalently‐linked dibenzo‐p‐dioxane architectures through intermolecular C–O–C coupling or two‐fold ...
Alberto Martínez‐Bajo   +14 more
wiley   +2 more sources

Modified Titanium Dental Implants: The Current Progress of Soft‐Tissue Integration Methods

open access: yesAdvanced NanoBiomed Research, EarlyView.
Dental implants are an established solution for tooth loss, yet achieving soft tissue integration (STI) around the transmucosal region remains a challenge. The natural tooth–gingiva interface is poorly replicated on titanium implants. This review explores surface modification strategies, ranging from surface chemistry and topography to biological ...
Daniel De Maria   +5 more
wiley   +1 more source

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

open access: yesAdvanced NanoBiomed Research, EarlyView.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source

A Philosophy of Informing Science [PDF]

open access: yesInforming Science: The International Journal of an Emerging Transdiscipline, 2009
openaire   +1 more source

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