Results 21 to 30 of about 13,902 (285)

Effect of Different Amino Acids and Heating Conditions on the Formation of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and Its Kinetics Formation Using Chemical Model System

Molecules, 2019
The formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) was investigated using a kinetic study approach as described by first-order, Arrhenius, and Eyring equations.
Ainaatul Asmaa Ishak, Jinap Selamat, Rabiha Sulaiman, Rashidah Sukor, Emilia Abdulmalek, Nuzul Noorahya Jambari   +5 more
doaj   +2 more sources

Glucuronidation of PhIP and N-OH-PhIP by UDP-glucuronosyltransferase 1A10 [PDF]

Carcinogenesis, 2007
The UDP-glucuronosyltransferase (UGT) 1A10 is an extra-hepatic enzyme that plays an important role in the glucuronidation of a variety of endogenous and exogenous substances and is expressed throughout the aerodigestive and digestive tracts. Two classes of carcinogens that target the colon, heterocyclic amines (HCAs) and polycyclic aromatic ...
Ryan W. Dellinger, Gong Chen, Andrea S. Blevins‐Primeau, Jacek Krzeminski, S. G. AMIN, P. Lazarus   +5 more
openalex   +4 more sources

circPHIP promotes oral squamous cell carcinoma progression by sponging miR-142-5p and regulating PHIP and ACTN4 expression

Molecular Therapy: Nucleic Acids, 2021
Circular RNA (circRNA) is a newly discovered class of noncoding RNAs that plays key regulatory role in pathological development, including the regulation of several solid tumors. However, the effects of circRNA expression on oral squamous cell carcinoma (
Wen Su, Yuehong Shen, Yufan Wang, Feng Wang, Xia Hong, Yuling Chen, Yuntao Lin, Hongyu Yang   +7 more
doaj   +2 more sources

Role of Furfural and 5-Methyl-2-furfural in Glucose-Induced Inhibition of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Formation in Chemical Models and Pork Patties [PDF]

Molecules
The effects of furfural and 5-methyl-2-furfural produced by the Maillard reaction on PhIP formation were investigated in chemical models and roasted pork patties.
Yuexia Qin, Zhuyu Zheng, Di Liu, Shuhua Sun, Xiaolei Zhao, Lei Lv, Dengyu Xie, Zhonghui Han, Jinxing He   +8 more
doaj   +2 more sources

Exploring the functional variations of key candidate genes affecting egg production by hypothalamic-pituitary-ovarian axis in chickens [PDF]

Poultry Science
Potential genetic variants associated with chicken egg production traits have been extensively identified, most of which are located in the non-coding regions of the genome.
Dandan Wang, Yiqian Zhu, Jiajia Dong, Yihao Zhi, Guanghui Wei, Xiangtao Kang, Xiaojun Liu   +6 more
doaj   +2 more sources

Pathogenic PHIP Variants are Variably Associated With CAKUT

Kidney International Reports
Introduction: Congenital anomalies of the kidney and urinary tract (CAKUT) represent the most common cause of chronic kidney disease in children.
Jonathan de Fallois, Tobias Sieckmann, Ria Schönauer, Friederike Petzold, Johannes Münch, Melissa Pauly, Georgia Vasileiou, Christin Findeisen, Antje Kampmeier, Alma Kuechler, André Reis, Eva Decker, Carsten Bergmann, Konrad Platzer, Velibor Tasic, Karin Michaela Kirschner, Shirlee Shril, Friedhelm Hildebrandt, Wendy K. Chung, Jan Halbritter   +19 more
doaj   +4 more sources

Grape seed extract ameliorates PhIP-induced colonic injury by modulating gut microbiota, lipid metabolism, and NF-κB signaling pathway in rats

, 2021
2-Amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) is a common carcinogen produced in thermally processed protein-rich foods. This study explored the protective effects of grape seed extract (GSE) against colonic injury induced by short-term ...
Xiuli Zhao, Yuekun Wu, Hengchao Liu, Nan Hu, Yan Zhang, Shuo Wang   +5 more
openalex   +2 more sources

Towards a unified picture of polarization transfer - pulsed DNP and chemically equivalent PHIP. [PDF]

Journal of magnetic resonance (San Diego, Calif. 1997 : Print), 2023
Nuclear spin hyperpolarization techniques, such as dynamic nuclear polarization (DNP) and parahydrogen-induced polarization (PHIP), have revolutionized nuclear magnetic resonance and magnetic resonance imaging.
Martin C. Korzeczek, L. Dagys, Christoph Müller, B. Tratzmiller, Alon Salhov, T. Eichhorn, Jochen Scheuer, S. Knecht, M. Plenio, I. Schwartz   +9 more
semanticscholar   +1 more source

Ammonia and formaldehyde participate in the formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in addition to creati(ni)ne and phenylacetaldehyde

Food Chemistry, 2014
Rosario Zamora, Esmeralda Alcón, Francisco J Hidalgo   +2 more
exaly   +3 more sources

Determination of hydrogen exchange and relaxation parameters in PHIP complexes at micromolar concentrations [PDF]

Magnetic Resonance, 2021
Non-hydrogenative para-hydrogen-induced polarization (PHIP) is a fast, efficient and relatively inexpensive approach to enhance nuclear magnetic resonance (NMR) signals of small molecules in solution.
L. Sellies, R. L. E. G. Aspers, M. Tessari   +2 more
doaj   +1 more source