Results 41 to 50 of about 13,902 (285)
BMC Microbiology, 2019 Background Consuming red and processed meat has been associated with an increased risk of colorectal cancer (CRC), which is partly attributed to exposure to carcinogens such as heterocyclic amines (HCA) formed during cooking and preservation processes ...
Jianbo Zhang +6 more
doaj +1 more source
Frontiers in Microbiomes, 2023 IntroductionAnaerobutyricum hallii is a human gut commensal that transforms the heterocyclic amine 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP), a carcinogen from cooked meat.
Alejandro Ramirez Garcia +10 more
doaj +1 more source
Mouse models of colorectal cancer. [PDF]
, 2011 Colorectal cancer is one of the most common malignancies in the world. Many mouse models have been developed to evaluate features of colorectal cancer in humans. These can be grouped into genetically-engineered, chemically-induced, and inoculated models.
Koeffler, H Phillip +2 more
core +2 more sources
A computer program for grain-size data [PDF]
, 1965 The computer program presented here seeks to improve estimation of statistical parameters for grain-size data by use of interpolated values. Interpolation is made by fitting a series of overlapping parabolas to the data, and follows the method of Snyder
Schlee, John Stevens +1 more
core +1 more source
PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance The development of targeted therapies represents a major advance in cancer therapy, with its most prominent examples including agents targeting HER2 in breast cancer, EGFR and ALK in lung cancer, and BRAF in melanoma.
David de Semir +16 more
openalex +3 more sources
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies. [PDF]
Ann Clin Transl NeurolABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Gilligan M +22 more
europepmc +2 more sources
analytical solutions for spectral patterns and their field dependence [PDF]
, 2012 We have obtained analytical solutions for Para-Hydrogen Induced Polarization (PHIP) for several types of coupled spin systems, namely, for AB-, ABX-, AA´A´´- and A2B-systems.
Ivanov, Konstantin L. +2 more
core +1 more source
Parahydrogen discriminated PHIP at low magnetic fields
Journal of Magnetic Resonance, 2015 Parahydrogen induced polarization (PHIP) is a powerful hyperpolarization technique. However, as the signal created has an anti-phase characteristic, it is subject to signal cancellation when the experiment is carried out in inhomogeneous magnetic fields or in low fields that lack the necessary spectral resolution.
Prina, Ignacio +2 more
openaire +4 more sources
A disintegrin derivative as a case study for PHIP labeling of disulfide bridged biomolecules
Scientific Reports, 2022 A specific labeling strategy for bioactive molecules is presented for eptifibatide (integrilin) an antiplatelet aggregation inhibitor, which derives from the disintegrin protein barbourin in the venom of certain rattlesnakes. By specifically labeling the
Max Fleckenstein +7 more
doaj +1 more source
eLife, 2020 The identification of autoantigens remains a critical challenge for understanding and treating autoimmune diseases. Autoimmune polyendocrine syndrome type 1 (APS1), a rare monogenic form of autoimmunity, presents as widespread autoimmunity with T and B ...
S. Vazquez +12 more
semanticscholar +1 more source