Results 81 to 90 of about 13,902 (285)

Polarized nuclear target based on parahydrogen induced polarization

, 2012
We discuss a novel concept of a polarized nuclear target for accelerator fixed-target scattering experiments, which is based on parahydrogen induced polarization (PHIP). One may be able to reach a 33% free-proton polarization in the ethane molecule.
Abbon, Abe, Abe, Adams, Adams, Adams, Airapetian, Airapetian, Airapetian, Alekseev, Alexakhin, Anselmino, Anthony, B. Wojtsekhowski, Bilenky, Bowers, Chen, Cloët, Collins, Crabb, Crabb, D. Budker, Derrick, Dolph, Gloggler, Goertz, Goez, Johnson, Keith, Kramer, Kulsrud, L.S. Bouchard, Ledbetter, Leemann, M.P. Ledbetter, Natterer, Rondon, S. Appelt, Sharma, Sivers, Steffens, Theis, Theis   +42 more
core   +1 more source

EGFR/MAPK signaling pathway acts as a potential therapeutic target for sulforaphane-rescued heart tube malformation induced by various concentrations of PhIP exposure [PDF]

, 2023
Guang Wang, Ran Zhao, Xinxia Zhang, Ying Zheng, Feiling Xie, Yu Jiang, Guohua Lv, Denglu Long, Chengyang Sun, Yongping Bao, Shuangyu Qi, Xinyue Liu, Qihao Zhang, Xuesong Yang   +13 more
openalex   +1 more source

The New England Knight: Sir William Phips, 1651-1695. [PDF]

The American Historical Review, 2000
Stephen Saunders Webb, Emerson W. Baker, John G. Reid   +2 more
openalex   +2 more sources

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

PhIP exposure in rodents produces neuropathology potentially relevant to Alzheimer's disease.

Toxicology, 2020
Alzheimer's disease (AD) is a public health crisis due debilitating cognitive symptoms and lack of curative treatments, in the context of increasing prevalence. Thus, it is critical to identify modifiable risk factors. High levels of meat consumption may
Tauqeerunnisa Syeda, R. Foguth, Emily Llewellyn, J. Cannon   +3 more
semanticscholar   +1 more source

Broadening the PHIP-Associated Neurodevelopmental Phenotype

Children
Background: Monoallelic damaging variants in PHIP (MIM*612870), encoding the Pleckstrin Homology Domain Interacting Protein, have been associated with a novel neurodevelopmental disorder, also termed Chung–Jansen syndrome (CHUJANS, MIM#617991). Most of the described individuals show developmental delay (DD)/intellectual disability (ID), obesity ...
Giulia Pascolini, Giovanni Luca Scaglione, Balasubramanian Chandramouli, Daniele Castiglia, Giovanni Di Zenzo, Biagio Didona   +5 more
openaire   +3 more sources

Schnelle RASER‐MRT

Angewandte Chemie, Volume 138, Issue 10, 2 March 2026.
Schnelle RASER‐MRT ermöglicht Bildgebung ohne RF‐Anregung. Stattdessen wird eine Populationsinversion der Kernspins durch SABRE‐Hyperpolarisation erzeugt, die eine Selbstanregung durch RASER ermöglicht. Wenn die gewünschte transversale Magnetisierung aufgebaut ist, wird herkömmliche EPI‐Kodierung ausgelöst, um das Bild aufzuzeichnen.
Sören Lehmkuhl, Simon Fleischer, Jing Yang, Eduard Y. Chekmenev, Thomas Theis, Stephan Appelt, Jan G. Korvink, Mazin Jouda   +7 more
wiley   +1 more source

Rapid RASER MRI

Angewandte Chemie International Edition, Volume 65, Issue 10, 2 March 2026.
Rapid RASER MRI allows for image acquisition without RF excitation. Instead, a population inversion on the nuclear spins is generated by SABRE hyperpolarization, which allows for self‐excitation through the RASER approach. When the desired transverse magnetization is built‐up, conventional EPI encoding is triggered to record the image.
Sören Lehmkuhl, Simon Fleischer, Jing Yang, Eduard Y. Chekmenev, Thomas Theis, Stephan Appelt, Jan G. Korvink, Mazin Jouda   +7 more
wiley   +1 more source

Chronic exposure to combined carcinogens enhances breast cell carcinogenesis with mesenchymal and stem-like cell properties. [PDF]

PLoS ONE, 2014
Breast cancer is the most common type of cancer affecting women in North America and Europe. More than 85% of breast cancers are sporadic and attributable to long-term exposure to small quantities of multiple carcinogens.
Lenora Ann Pluchino, Hwa-Chain Robert Wang   +1 more
doaj   +1 more source

Biomonitoring PhIP, a Potential Prostatic Carcinogen, in the Hair of Healthy Men of African and European Ancestry

Toxics
Heterocyclic aromatic amines (HAAs), formed during the cooking of meat, are potential human carcinogens, underscoring the need for long-lived biomarkers to assess exposure and cancer risk.
Robert J. Turesky, Clarence Jones, Jingshu Guo, Kari Cammerrer, Laura A. Maertens, Emmanuel S. Antonarakis, Zhanni Lu, Logan G. Spector   +7 more
doaj   +1 more source