Results 61 to 70 of about 11,552 (225)

The host-range tdCE phenotype of Chandipura virus is determined by mutations in the polymerase gene [PDF]

The emerging arbovirus Chandipura virus (CV) has been implicated in epidemics of acute encephalitis in India with high mortality rates. The isolation of temperature-dependent host-range (tdCE) mutants, which are impaired in growth at 39 °C in chick ...
Easton, A. J. (Andrew J.), Marriott, Anthony C., Stock, Emily   +2 more
core   +1 more source

The Regulatory Effect of Histone Deacetylase (HDAC) 1 and 2 on iNOS, IL‐6, TNF‐α and IL‐10 Expression in Canine Macrophages Infected With Leishmania infantum

Parasite Immunology, Volume 48, Issue 4, April 2026.
ABSTRACT Zoonotic visceral leishmaniasis is caused by Leishmania (Leishmania) infantum. Dogs are considered the most critical urban reservoirs of L. (L.) infantum due to their high infection rate and direct transmission to humans. The parasite has developed mechanisms to evade the host's defence system by inhibiting macrophage activation, thereby ...
Gabriela Lovizutto Venturin, Lucas Takeshi Siqueira Ito, Gisele Mitsue Umino, Gabriela Torres Rebech, Flávia Lombardi Lopes, Valéria Marçal Felix de Lima   +5 more
wiley   +1 more source

Genetic, serological and biochemical characterization of Leishmania tropica from foci in northern Palestine and discovery of zymodeme MON-307 [PDF]

, 2012
Background Many cases of cutaneous leishmaniasis (CL) have been recorded in the Jenin District based on their clinical appearance. Here, their parasites have been characterized in depth.
A Al-Jawabreh, A Al-Jawabreh, A Al-Jawabreh, A Warburg, Abedelmajeed Nasereddin, Christophe Ravel, CL Eisenberger, CL Jaffe, DE Dobson, DF Smith, E Cupolillo, EK Saliba, EK Saliba, F Pratlong, Fouad El Baidouri, Francine Pratlong, G Anders, G Schonian, G Schonian, Gabriele Schonian, IL Mauricio, J Felsenstein, JA Rioux, JA Rioux, Jean-Pierre Dedet, JM Schwenkenbecher, K Azmi, K Azmi, Kifaya Azmi, LF Schnur, LF Schnur, LF Schnur, LF Schnur, Lionel Schnur, M Rhajaoui, M Svobodova, MZ Alam, R Maazoun, RL Jacobson, RP Soares, S Adler, S Kamhawi, S Martinez-Calvillo, SM Le Blancq, SM Le Blancq, Suheir Ereqat, Y Schlein, Y Schlein, Ziad Abdeen   +48 more
core   +3 more sources

Synthesis and Evaluation of the First Generation of Glycosylated Nucleoside Analogues as Potential Inhibitors of the Base J Metabolism in Kinetoplastid Parasites

Chemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.
Novel analogues of the kinetoplastid‐specific DNA base J unlock a new way to target parasite epigenetic regulation. Some compounds selectively inhibit Leishmania and Trypanosoma species without harming human cells, revealing a promising route toward innovative antiparasitic therapies.
Océane Monfret, Dan Liu, Manon Louis, Sihem Rebei, Dominique Urban, Yann Bourdreux, Elisabeth Mouray, Philippe Grellier, Gilles Doisneau, Dominique Guianvarc'h   +9 more
wiley   +1 more source

Natural Leishmania (Viannia) infections of phlebotomines (Diptera: Psychodidae) indicate classical and alternative transmission cycles of American cutaneous leishmaniasis in the Guiana Shield, Brazil

Parasite, 2017
From 1996 to 1999 multi-trapping methods (Center of Diseases Control, CDC) light traps, light-baited Shannon traps, and aspiration on tree bases) were used to study the phlebotomine fauna of the “Serra do Navio” region of the Brazilian State of Amapá ...
de Souza Adelson Alcimar Almeida, da Rocha Barata Iorlando, das Graças Soares Silva Maria, Lima José Aprígio Nunes, Jennings Yara Lúcia Lins, Ishikawa Edna Aoba Yassui, Prévot Ghislaine, Ginouves Marine, Silveira Fernando Tobias, Shaw Jeffrey, dos Santos Thiago Vasconcelos   +10 more
doaj   +1 more source

Lutzomyia migonei is a permissive vector competent for Leishmania infantum [PDF]

, 2016
BACKGROUND: Leishmania infantum is the most widespread etiological agent of visceral leishmaniasis (VL) in the world, with significant mortality rates in human cases.
Jitka Myskova, Jovana Sadlova, Katerina Pruzinova, Petr Volf, Sinval Pinto Brandão Filho, Vanessa Cristina Fitipaldi Veloso Guimarães, Vera Volfova   +6 more
core   +1 more source

Quantitative phenetics and taxonomy of some phlebotomine taxa [PDF]

Memórias do Instituto Oswaldo Cruz, 1999
Elucidating the evolution of Phlebotominae is important not only to revise their taxonomy, but also to help understand the origin of the genus Leishmania and its relationship with humans. Our study is a phenetic portrayal of this history based on the genetic relationships among some New Word and Old Word taxa.
/Dujardin, Jean-Pierre, /Le Pont, François, Martinez, E.   +2 more
openaire   +6 more sources

Exploring Novel Nitrofuryl‐1,3,4‐Thiadiazole‐Based Derivatives: Design, Synthesis, and Evaluation of In Vitro Leishmanicidal and Trypanocidal Activity

Archiv der Pharmazie, Volume 359, Issue 3, March 2026.
In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi, Martina Slapničková, Maryam Norouzbahari, Sarah D'Alessandro, Parham Foroumadi, Fariba Peytam, Federica Perego, Eva Doleželová, Zahra Emamgholipour, Maliheh Barazandeh Tehrani, Seyed Esmaeil Sadat‐Ebrahimi, Elahe Hosseinzadeh, Elmira Meghrazi Ahadi, Loghman Firoozpour, Hamidreza Bijanzadeh, Nicoletta Basilico, Alena Zíková, Alireza Foroumadi   +17 more
wiley   +1 more source

Establishment and characterization of a new continuous cell line from Lutzomyia longipalpis (Diptera: Psychodidae) and its susceptibility to infections with arboviruses and Leishmania chagasi

Memorias do Instituto Oswaldo Cruz, 2000
Embryonic tissue explants of the sand fly Lutzomyia longipalpis (Lutz & Neiva 1912) the main vector of Leishmania chagasi (Cunha and Chagas), were used to obtain a continuous cell line (Lulo).
Rey Gloria J, Ferro Cristina, Bello Felio J   +2 more
doaj  

Influência da reorganização, da limpeza do peridomicílio e a da desinsetização de edificações na densidade populacional de flebotomíneos no Município de Doutor Camargo, Estado do Paraná, Brasil Influence of rearrangement and cleaning of the peridomiciliary area and building disinsectization on sandfly population density in the municipality of Doutor Camargo, Paraná State, Brazil

Cadernos de Saúde Pública, 2003
Comparam-se os resultados de coletas de flebotomíneos, feitas com armadilhas de Falcão, no domicílio e em abrigos de animais domésticos no peridomicílio, antes e após a reorganização, a limpeza e a desinsetização destes ambientes.
Ueslei Teodoro, Thaís Gomes Verzignassi Silveira, Demilson Rodrigues dos Santos, Elcio Silvestre dos Santos, Ademar Rodrigues dos Santos, Otílio de Oliveira, João B. Kühl, Dayane Alberton   +7 more
doaj   +1 more source