Results 51 to 60 of about 13,380 (269)

Harnessing controlled human infection models to accelerate vaccine development for neglected tropical diseases: Lessons from leishmaniasis

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Controlled Human Infection Models (CHIMs) offer a powerful approach to accelerate vaccine development for neglected tropical diseases (NTDs). This review highlights scientific and translational advances enabled by CHIMs, with a focus on a novel Leishmania major model.
Vivak Parkash
wiley   +1 more source

Diversity of Phlebotomine sand flies (Diptera: Psychodidae) in mountainous and plain areas of an endemic focus of anthroponotic cutaneous leishmaniasis in Iran

Asian Pacific Journal of Tropical Biomedicine, 2020
Objective: To determine the diversity of sand flies in different biotopes of mountainous and plain areas of Bam County as the most infected focus of anthroponotic cutaneous leishmaniasis in southeast Iran, and synanthropic index of Phlebotomus sergenti ...
Saideh Yousefi, Ali Reza Zahraei-Ramazani, Yavar Rassi, Mohammad Reza Aflatoonian, Mohammad Reza Yaghoobi-Ershadi, Abbas Aghaei-Afshar, Amir Ahmad Akhavan, Masoumeh Amin, Azim Paksa   +8 more
doaj   +1 more source

Phlebotomine sandflies (Diptera: Psychodidae) of Ethiopia

Heliyon, 2023
Phlebotomine sandflies have a long history of association with humans, which makes them the only proven natural vectors of Leishmania species, the parasitic protozoans that cause leishmaniases in humans and animals.
Esayas Aklilu, Solomon Yared, Araya Gebresilassie, Behailu Legesse, Asrat Hailu   +4 more
doaj   +1 more source

Viola phlebovirus is a novel Phlebotomus fever serogroup member identified in Lutzomyia (Lutzomyia) longipalpis from Brazilian Pantanal

Parasites & Vectors, 2018
High throughput sequencing (HTS) boosted the discovery of novel viruses and new variants of known viruses. Here we investigated the presence of viruses in 12 pools of sand flies captured in three climatic periods in RAPELD grids at Rio Claro, Chapada dos
M. S. de Carvalho, Andressa Z. de Lara Pinto, Aquirya Pinheiro, J. S. V. Rodrigues, F. L. Melo, Leonardo A. da Silva, B. Ribeiro, Renata Dezengrini-Slhessarenko   +7 more
semanticscholar   +1 more source

Sex in Immune Cells and Parasitic Diseases — A Complex Relationship

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker, Charlotte Sophie Hansen, Hanna Lotter   +2 more
wiley   +1 more source

The Safety and Efficacy of an Immunomodulator Garlic‐Based Cream (LeishG1) for Treating Uncomplicated Cutaneous Leishmaniasis: A Single‐Blind, Multi‐Center Study

Health Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Cutaneous leishmaniasis (CL) is a major problem in developing nations, particularly in the Middle East. Novel herbal treatment options may provide a safe alternative associated with favorable outcomes in CL lesion healing.
Fatemeh Emadi, Zohreh Khodashenas, Azadeh Rashidi, Ali Khamesipour, Mehdi Zaboli, Mehri Ghafourian, Mohammad Mehdi Naghizadeh, Fatemeh Tuserkani, Tooba Ghazanfari   +8 more
wiley   +1 more source

Species composition of sand flies and bionomics of Phlebotomus papatasi and P. sergenti (Diptera: Psychodidae) in cutaneous leishmaniasis endemic foci, Morocco

Parasites & Vectors, 2016
BackgroundCutaneous Leishmaniasis (CL) is one of the most neglected tropical diseases in Morocco. Leishmania major and L. tropica are the main culprits identified in all endemic foci across the country.
S. Boussaa, K. Kahime, A. Samy, Abdelkrim Ben Salem, A. Boumezzough   +4 more
semanticscholar   +2 more sources

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source

The current status of phlebotomine sand flies in Albania and incrimination of Phlebotomus neglectus (Diptera, Psychodidae) as the main vector of Leishmania infantum

PLoS ONE, 2017
The incidence of visceral leishmaniasis (VL) in Albania is higher than in other countries of southern Europe, however the role of local sand fly species in the transmission of Leishmania infantum was not addressed conclusively.
E. Velo, G. Bongiorno, P. Kadriaj, T. Myrseli, J. Crilly, A. Lika, K. Mersini, T. Di Muccio, S. Bino, M. Gramiccia, L. Gradoni, M. Maroli   +11 more
semanticscholar   +1 more source

A Forgotten Foe Returns: The Diagnostic Odyssey of Kala‐Azar Masquerading as Myelodysplastic Syndrome in a Post‐Elimination Era

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT We report a diagnostically complex case of visceral leishmaniasis (Kala‐azar) in a 73‐year‐old male from a country where the disease was eliminated in 2023. The patient presented with a 2‐month history of low‐grade fever, fatigue, progressive skin hyperpigmentation over 2 years, and hepatosplenomegaly.
Sumaya Khan Mifty, Saiful Islam Chowdhury, Tahmidur Rahman, Tanveer Al Razi Khan, Swagota Roy, Faiza Ahmmed, Md. Sabbir Hossain, Ibrahim Khalil   +7 more
wiley   +1 more source