Results 51 to 60 of about 31,760 (239)

Gamma‐glutamyltransferase and immunoglobulin G in intestinal maturation: Pilot study in preterm and term infants and the influence of breast milk

JPGN Reports, EarlyView.
Abstract Gamma‐glutamyltransferase (γGT), a key enzyme in glutathione metabolism, is abundant in colostrum and may indicate neonatal gastrointestinal maturation, although normative serum values and associations with breast milk intake remain unclear, particularly in preterm infants.
Johanna Jakobs, Teresa Riedl‐Seifert, Franziska Jakobs, Markus Waitz, Andreas Jenke   +4 more
wiley   +1 more source

Different effect of hydroxyurea and phlebotomy on prevention of arterial and venous thrombosis in Polycythemia Vera

Blood Cancer Journal, 2018
Clonal proliferation of hematopoietic precursors leading to progressive expansion of myeloid cells with a predominant increase of red cells characterizes the hematological phenotype of Polycythemia Vera (PV). The resulting blood hyperviscosity is a major
T. Barbui, V. De Stefano, A. Ghirardi, A. Masciulli, G. Finazzi, A. Vannucchi   +5 more
semanticscholar   +1 more source

JAK2 Variant and Parkinsonian Syndromes: Coincidence or Pathophysiological Link?

Movement Disorders Clinical Practice, EarlyView.
Abstract Background JAK2 variants are a hallmark of myeloproliferative neoplasms (MPNs), including polycythemia vera and essential thrombocythemia. These disorders are often associated with thrombotic and inflammatory complications. From a movement disorder perspective, chorea is a rare but well‐recognized neurological occurrence in this context ...
Elena Ardila Jurado, Koustubh Bavdhankar, Divyani Garg, Francesca Magrinelli, Huw R. Morris, Kailash P. Bhatia   +5 more
wiley   +1 more source

The impact of phlebotomy and hydroxyurea on survival and risk of thrombosis among older patients with polycythemia vera.

Blood Advances, 2018
Current guidelines recommend therapeutic phlebotomy for all polycythemia vera (PV) patients and additional cytoreductive therapy (eg, hydroxyurea [HU]) for high-risk PV patients.
N. Podoltsev, Mengxin Zhu, A. Zeidan, Rong Wang, Xiaoyi Wang, A. Davidoff, S. Huntington, S. Giri, S. Gore, Xiao-Mei Ma   +9 more
semanticscholar   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Oral Microalgae‐Laden Hydrogels Modulating the Intestinal Microbiota Metabolism for Acute Alcohol‐Induced Liver Injury Therapy

Small, EarlyView.
A food‐grade microalgae‐laden hydrogel (FMH) enables efficient in situ microalgae cultivation and serves as an oral therapeutic platform for acute alcohol‐induced liver injury. FMH improves alcohol tolerance, alleviates oxidative stress, inflammation, and lipid metabolic disorders, restores gut microbial homeostasis, and provides synergistic ...
Zhixin Hu, Hongtao Wu, Xuanqi Liu, Xinxu Huang, Linli Jiang, Lei Liu, Xiaojie Li, Yawen Yao, Fengzheng Gao, Kui Zeng, Jiajing Zhou   +10 more
wiley   +1 more source

Effect of Therapeutic Phlebotomy on the Haematological Parameters in Polycythaemia Cases: A Cross-sectional Study from a Tertiary Blood Centre in Southern India [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Therapeutic phlebotomy involves the controlled removal of blood from a patient to reduce complications in polycythemia, in which 300 to 400 mL of blood is removed.
Padmini Chitradurga Vijayasarathy, Haroon Adoni, Brilsee Simeon   +2 more
doaj   +1 more source

Phlebotomy as a preventive measure for crocidolite‐induced mesothelioma in male rats

Cancer Science, 2018
Malignant mesothelioma (MM) is a rare but socially important neoplasm due to its association with asbestos exposure. Malignant mesothelioma is difficult to diagnose at an early stage, yet there are no particularly effective treatments available at the ...
Yuuki Ohara, S. Chew, T. Shibata, Yasumasa Okazaki, K. Yamashita, S. Toyokuni   +5 more
semanticscholar   +1 more source

Evaluation of the collection and storage of packed red blood cells in ferrets

Veterinary Record, EarlyView.
Abstract Background Blood transfusion is lifesaving in anaemic ferrets, but species‐specific blood‐banking systems are lacking, and optimal storage conditions for packed red blood cells (pRBCs) have not been established. Therefore, this study aimed to assess the bacteriological, biochemical and haematological stability of pRBC stored in citrate ...
Audrey Alsac, Sylvain Bellier, Thomas M. Donnelly, Charly Pignon   +3 more
wiley   +1 more source

Diagnostic Lag in Precision Medicine

Clinical Pharmacology &Therapeutics, EarlyView.
Petr Heneberg
wiley   +1 more source