Results 91 to 100 of about 7,085 (250)

Activation of PKR by Bunyamwera virus is independent of the viral interferon antagonist NSs [PDF]

, 2003
Double-stranded RNA (dsRNA) is a by-product of viral RNA polymerase activity, and its recognition is one mechanism by which the innate immune system is activated.
Boyd, Amanda, Bridgen, Anne, Elliott, Richard M, Fazakerley, John K, Streitenfeld, Hein, Weber, Friedemann   +5 more
core   +3 more sources

HSP90 is part of a protein complex with the L polymerase of Rift Valley fever phlebovirus and prevents its degradation by the proteasome during the viral genome replication/transcription stage

Frontiers in Cellular and Infection Microbiology
The mosquito-borne Rift Valley fever virus (RVFV) from the Phenuiviridae family is a single-stranded RNA virus that causes the re-emerging zoonotic disease Rift Valley fever (RVF).
Farhang Alem, Ashwini Brahms, Kaori Tarasaki, Samson Omole, K. Kehn-Hall, Connie S. Schmaljohn, Sina Bavari, Shinji Makino, R. Hakami   +8 more
semanticscholar   +1 more source

Melittin-Related Peptides Interfere with Sandfly Fever Naples Virus Infection by Interacting with Heparan Sulphate

Microorganisms, 2023
Emerging viruses pose an important global public health challenge, and early action is needed to control their spread. The Bunyaviridae family contains a great number of arboviruses which are potentially pathogenic for humans.
Annalisa Chianese, Carla Zannella, Francesca Palma, Laura Di Clemente, Alessandra Monti, Nunzianna Doti, Anna De Filippis, Massimiliano Galdiero   +7 more
doaj   +1 more source

Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite Leishmania. [PDF]

, 2018
Knowledge of viral diversity is expanding greatly, but many lineages remain underexplored. We surveyed RNA viruses in 52 cultured monoxenous relatives of the human parasite <i>Leishmania</i> ( <i>Crithidia</i> and <i> ...
Akopyants, N.S., Beverley, S.M., Butenko, A., d'Avila-Levy, C.M., Dobson, D.E., Fasel, N., Frolov, A.O., Grybchuk, D., Konovalovas, A., Kostygov, A.Y., Kulich, P., Lukeš, J., Lye, L.F., Moravcová, J., Plevka, P., Rogozin, I.B., Serva, S., Votýpka, J., Yurchenko, V., Zangger, H.   +19 more
core   +1 more source

Viral metagenomic analysis of feces of wild small carnivores [PDF]

, 2014
Background: Recent studies have clearly demonstrated the enormous virus diversity that exists among wild animals. This exemplifies the required expansion of our knowledge of the virus diversity present in wildlife, as well as the potential transmission ...
Bodewes, Rogier, Osterhaus, Albert DME, Ruiz González, Aritz, Schapendonk, Claudia ME, Smits, Saskia L., Van den Brand, Judith MA   +5 more
core   +8 more sources

Vírus Toscana: dez anos de diagnóstico em Portugal [PDF]

, 2021
[EN] Introduction: Toscana virus (TOSV) is an emerging sandfly-borne virus within the Phlebovirus genus. Although most infections caused by this virus present as asymptomatic or with minimal symptomatology, TOSV may emerge as a febrile disease or ...
Alves, Maria João, Amaro, Fátima, Luz, Maria Teresa, Zé-Zé, Líbia   +3 more
core   +1 more source

Establishment of an Early Prediction Model for Severe Fever With Thrombocytopenia Syndrome‐Associated Encephalitis

Immunity, Inflammation and Disease, Volume 12, Issue 12, December 2024.
ABSTRACT Background Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease primarily transmitted by ticks. The development of encephalitis in SFTS patients significantly increases the risk of adverse outcomes. However, the understanding of SFTS‐associated encephalitis (SFTSAE) is still limited. This study aimed to identify
Yijiang Liu, Naisheng Zhu, Zimeng Qin, Chenzhe He, Jiaqi Li, Hongbo Zhang, Ke Cao, Wenkui Yu   +7 more
wiley   +1 more source

Diverse novel phleboviruses in sandflies from the Panama Canal area, Central Panama [PDF]

, 2019
The genus Phlebovirus (order Bunyavirales, family Phenuiviridae) comprises 57 viruses that are grouped into nine speciescomplexes. Sandfly-transmitted phleboviruses are found in Europe, Africa and the Americas and are responsible for febrile illness and ...
Dutari, Larissa C., Junglen, Sandra, Loaiza, Jose R., Marklewitz, Marco, Paraskevopoulou, Sofia   +4 more
core   +1 more source

2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales [PDF]

, 2022
In March 2022, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended.
Adkins, Scott, Alkhovsky, Sergey V., Avšič-Županc, Tatjana, Ayllón, María A., Bahl, Justin, Balkema-Buschmann, Anne, Ballinger, Matthew J., Bandte, Martina, Beer, Martin, Bejerman, Nicolas Esteban, Kuhn, Jens H., Lodden Økland, Arnfnn   +11 more
core   +1 more source

Early prognosis biomarkers of severe fever with thrombocytopenia syndrome

iLABMED, Volume 2, Issue 4, Page 341-351, December 2024.
SFTSV interacts with the host's immune defenses, prompting the engagement of both innate and adaptive immune responses by effector cells. This interaction ultimately results in the activation and proliferation of relevant cytokines. Abstract Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that results from SFTS ...
Mingrong Ou, Aofan Wang, Jie Yu, Liwei Zhao, Chuang Li, Yuanyuan Wu, Yuxin Chen   +6 more
wiley   +1 more source