Results 81 to 90 of about 28,799 (193)

Lettuce Big‐Vein Associated Virus ORF3 Encodes a Functional 30K Movement Protein

Molecular Plant Pathology, Volume 26, Issue 9, September 2025.
AlphaFold2 + FoldSeek structure guided search predicts the movement protein of lettuce big‐vein associated virus despite low sequence similarity. ABSTRACT Movement proteins (MPs) modulate the size exclusion limit of plasmodesmata—membrane‐lined channels connecting plant cells—thereby allowing cell‐to‐cell movement and systemic spread of plant viruses ...
Willem E. W. Schravesande, Machiel V. Cligge, Raoul Frijters, Adriaan Verhage, Harrold A. van den Burg   +4 more
wiley   +1 more source

Amazonian Phlebovirus (Bunyaviridae) potentiates the infection of Leishmania (Leishmania) amazonensis: Role of the PKR/IFN1/IL-10 axis.

, 2019
Leishmania parasites are transmitted to vertebrate hosts by phlebotomine sandflies and, in humans, may cause tegumentary or visceral leishmaniasis. The role of PKR (dsRNA activated kinase) and Toll-like receptor 3 (TLR3) activation in the control of ...
Rath, C.T., Pereira, RMS, de Arruda, L.B., Vivarini, Á.C., Gomes, C., Damaso, C.R., Laurenti, M.D., Fasel, N., Schnellrath, L.C., Vasconcelos, PFDC, Calegari Silva, T.C., Lopes, U.G.   +11 more
core   +2 more sources

Medicinal Plant‐Derived Caffeoylquinic Acids as Inhibitors of Rift Valley Fever Virus: A Computational Study

ChemistrySelect, Volume 10, Issue 12, March 26, 2025.
Caffeoylquinic acids derived from medicinal plants were evaluated for their potential as inhibitors of the Rift Valley Fever Virus, specifically targeting the LRP1‐CR17 protein. The study employed DFT, molecular docking, and molecular dynamics simulations to analyze these compounds. The results showed strong binding affinities to the LRP1‐CR17 receptor,
Garland K. More, Charmy Twala, Kgaugelo C. Tapala, Raymond T. Makola, Gerhard Prinsloo   +4 more
wiley   +1 more source

Overview of West Nile Virus and Sandfly-borne Phlebovirus Infections in Anatolia

Journal of Microbiology and Infectious Diseases, 2014
Arthropod-borne (arbo) viruses are trafinsmitted to the susceptible hosts by blood-feeding arthropods such as mosquitoes, sandflies and ticks. Arboviral infections have had a significant global public health impact during the last decades due to their ...
Koray Ergunay, Zeliha Kocak Tufan
doaj   +1 more source

Comparative production analysis of three phlebovirus nucleoproteins under denaturing or non-denaturing conditions for crystallographic studies. [PDF]

, 2011
Nucleoproteins (NPs) encapsidate the Phlebovirus genomic (-)RNA. Upon recombinant expression, NPs tend to form heterogeneous oligomers impeding characterization of the encapsidation process through crystallographic studies.
Lantez Violaine, Canard Bruno, Karen Dalle, Bruno Coutard, Cécile Baronti, Charrel Rémi, Violaine Lantez, Bruno Canard, Rémi Charrel, Coutard Bruno, Baronti Cécile, Dalle Karen   +11 more
core   +1 more source

Single-Dose Intranasal Treatment with DEF201 (Adenovirus Vectored Consensus Interferon) Prevents Lethal Disease Due to Rift Valley Fever Virus Challenge

Viruses, 2014
Rift Valley fever virus (RVFV) causes severe disease in humans and ungulates. The virus can be transmitted by mosquitoes, direct contact with infected tissues or fluids, or aerosol, making it a significant biological threat for which there is no approved
Brian B. Gowen, Jane Ennis, Kevin W. Bailey, Zachary Vest, Dionna Scharton, Eric J. Sefing, Jeffrey D. Turner   +6 more
doaj   +1 more source

Ticks From Mink and Their Associated Microorganisms in Spain

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Wildlife is an important source of emerging zoonotic agents, including tick‐borne ones. Wild carnivores such as mink are commonly parasitized by ticks, which are vectors and reservoirs of zoonotic diseases. Besides the importance of these arthropods as potential sources of diseases in mink, and the role of these mammals as reservoirs of infectious ...
Ana M. Palomar, Aránzazu Portillo, Asunción Gómez, Madis Põdra, Paula Santibáñez, Cristina Cervera-Acedo, Sonia Santibáñez, Elena López, Manena Fayos, José A. Oteo, Yongguo Cao   +10 more
wiley   +1 more source

Novel Phlebovirus in Febrile Child, Greece

Emerging Infectious Diseases, 2011
To the Editor: Phleboviruses (family Bunyaviridae, genus Phlebovirus) are arthropod-borne, single-stranded, RNA viruses. Their genome consists of 3 segments—small, medium, and large—which encode the nucleoprotein and nonstructural proteins, the envelope glycoproteins, and the viral polymerase, respectively (1).
Vassiliki Anagnostou, Grigorios Pardalos, Miranda Athanasiou-Metaxa, Anna Papa   +3 more
openaire   +2 more sources

Experimental Infection of Dogs with Toscana Virus and Sandfly Fever Sicilian Virus to Determine Their Potential as Possible Vertebrate Hosts

Microorganisms, 2020
The sandfly-borne Toscana phlebovirus (TOSV), a close relative of the sandfly fever Sicilian phlebovirus (SFSV), is one of the most common causes of acute meningitis or meningoencephalitis in humans in the Mediterranean Basin.
Clara Muñoz, Nazli Ayhan, Maria Ortuño, Juana Ortiz, Ernest A. Gould, Carla Maia, Eduardo Berriatua, Remi N. Charrel   +7 more
doaj   +1 more source

Establishment of an Early Prediction Model for Severe Fever With Thrombocytopenia Syndrome‐Associated Encephalitis

Immunity, Inflammation and Disease, Volume 12, Issue 12, December 2024.
ABSTRACT Background Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease primarily transmitted by ticks. The development of encephalitis in SFTS patients significantly increases the risk of adverse outcomes. However, the understanding of SFTS‐associated encephalitis (SFTSAE) is still limited. This study aimed to identify
Yijiang Liu, Naisheng Zhu, Zimeng Qin, Chenzhe He, Jiaqi Li, Hongbo Zhang, Ke Cao, Wenkui Yu   +7 more
wiley   +1 more source